标题
Mechanisms and Therapy for Cancer Metastasis to the Brain
作者
关键词
-
出版物
Frontiers in Oncology
Volume 8, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2018-05-24
DOI
10.3389/fonc.2018.00161
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Overall Survival in Patients With Advanced Melanoma Who Received Nivolumab Versus Investigator’s Choice Chemotherapy in CheckMate 037: A Randomized, Controlled, Open-Label Phase III Trial
- (2018) James Larkin et al. JOURNAL OF CLINICAL ONCOLOGY
- Edoxaban for the Treatment of Cancer-Associated Venous Thromboembolism
- (2018) Gary E. Raskob et al. NEW ENGLAND JOURNAL OF MEDICINE
- The efficacy of lapatinib and capecitabine in HER-2 positive breast cancer with brain metastases: A systematic review and pooled analysis
- (2017) Fausto Petrelli et al. EUROPEAN JOURNAL OF CANCER
- Efficacy of the combination of ipilimumab and nivolumab following progression on pembrolizumab in advanced melanoma with poor risk features
- (2017) Lavinia Spain et al. EUROPEAN JOURNAL OF CANCER
- Afatinib Therapy for Brain Metastases Aggravated by a Reduction in the Dose of Erlotinib Due to the Development of Hepatotoxicity
- (2017) Yumie Yamanaka et al. INTERNAL MEDICINE
- Stereotactic Radiosurgery With or Without Whole-Brain Radiation Therapy for Limited Brain Metastases: A Secondary Analysis of the North Central Cancer Treatment Group N0574 (Alliance) Randomized Controlled Trial
- (2017) Thomas M. Churilla et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Estimating Survival in Melanoma Patients With Brain Metastases: An Update of the Graded Prognostic Assessment for Melanoma Using Molecular Markers (Melanoma-molGPA)
- (2017) Paul W. Sperduto et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Targeting the tumor microenvironment as a potential therapeutic approach in colorectal cancer: Rational and progress
- (2017) Afsane Bahrami et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Osimertinib in Pretreated T790M-Positive Advanced Non–Small-Cell Lung Cancer: AURA Study Phase II Extension Component
- (2017) James Chih-Hsin Yang et al. JOURNAL OF CLINICAL ONCOLOGY
- Brigatinib in Patients With Crizotinib-Refractory Anaplastic Lymphoma Kinase–Positive Non–Small-Cell Lung Cancer: A Randomized, Multicenter Phase II Trial
- (2017) Dong-Wan Kim et al. JOURNAL OF CLINICAL ONCOLOGY
- Applications of DNA-Based Liquid Biopsy for Central Nervous System Neoplasms
- (2017) Joanna Wang et al. JOURNAL OF MOLECULAR DIAGNOSTICS
- Anticoagulation for the treatment of venous thromboembolism in patients with brain metastases: a meta-analysis and systematic review
- (2017) Bradley D. Hunter et al. JOURNAL OF THROMBOSIS AND THROMBOLYSIS
- First-line ceritinib versus platinum-based chemotherapy in advanced ALK -rearranged non-small-cell lung cancer (ASCEND-4): a randomised, open-label, phase 3 study
- (2017) Jean-Charles Soria et al. LANCET
- Pembrolizumab versus ipilimumab for advanced melanoma: final overall survival results of a multicentre, randomised, open-label phase 3 study (KEYNOTE-006)
- (2017) Jacob Schachter et al. LANCET
- Alectinib versus crizotinib in patients with ALK -positive non-small-cell lung cancer (J-ALEX): an open-label, randomised phase 3 trial
- (2017) Toyoaki Hida et al. LANCET
- Postoperative stereotactic radiosurgery compared with whole brain radiotherapy for resected metastatic brain disease (NCCTG N107C/CEC·3): a multicentre, randomised, controlled, phase 3 trial
- (2017) Paul D Brown et al. LANCET ONCOLOGY
- Lorlatinib in non-small-cell lung cancer with ALK or ROS1 rearrangement: an international, multicentre, open-label, single-arm first-in-man phase 1 trial
- (2017) Alice T Shaw et al. LANCET ONCOLOGY
- Treatment options for EGFR mutant NSCLC with CNS involvement—Can patients BLOOM with the use of next generation EGFR TKIs?
- (2017) Chee-Seng Tan et al. LUNG CANCER
- Paradigm shift of therapeutic management of brain metastases in EGFR-mutant non-small cell lung cancer in the era of targeted therapy
- (2017) Akimasa Sekine et al. MEDICAL ONCOLOGY
- Diagnosis and treatment of brain metastases from solid tumors: guidelines from the European Association of Neuro-Oncology (EANO)
- (2017) Riccardo Soffietti et al. NEURO-ONCOLOGY
- Cerebrospinal fluid circulating tumor cells: a novel tool to diagnose leptomeningeal metastases from epithelial tumors
- (2017) Xuling Lin et al. NEURO-ONCOLOGY
- Three or More Courses of Stereotactic Radiosurgery for Patients with Multiply Recurrent Brain Metastases
- (2017) Rupesh Kotecha et al. NEUROSURGERY
- Treatment of brain metastases in the modern genomic era
- (2017) Ibiayi Dagogo-Jack et al. PHARMACOLOGY & THERAPEUTICS
- Stereotactic radiosurgery versus whole-brain radiotherapy after intracranial metastasis resection: a systematic review and meta-analysis
- (2017) Nayan Lamba et al. Radiation Oncology
- Icotinib versus whole-brain irradiation in patients with EGFR -mutant non-small-cell lung cancer and multiple brain metastases (BRAIN): a multicentre, phase 3, open-label, parallel, randomised controlled trial
- (2017) Jin-Ji Yang et al. Lancet Respiratory Medicine
- Erlotinib and bevacizumab in patients with advanced non-small-cell lung cancer and activating EGFR mutations (BELIEF): an international, multicentre, single-arm, phase 2 trial
- (2017) Rafael Rosell et al. Lancet Respiratory Medicine
- Estimating Survival in Patients With Lung Cancer and Brain Metastases
- (2017) Paul W. Sperduto et al. JAMA Oncology
- Concurrent Afatinib and Whole-Brain Radiotherapy in Exon 19-del-EGFR Mutant Lung Adenocarcinoma: A Case Report and Mini Review of the Literature
- (2017) Chukwuka Eze et al. Frontiers in Oncology
- Vemurafenib in Metastatic Melanoma Patients with Brain Metastases: An Open-Label, Single-Arm, Phase 2, Multicentre Study
- (2016) GA McArthur et al. ANNALS OF ONCOLOGY
- Histopathologic diagnosis of brain metastases: current trends in management and future considerations
- (2016) Lien Bekaert et al. Brain Tumor Pathology
- Risk factors for brain metastasis as a first site of disease recurrence in patients with HER2 positive early stage breast cancer treated with adjuvant trastuzumab
- (2016) Onder Tonyali et al. BREAST
- Timing and type of immune checkpoint therapy affect the early radiographic response of melanoma brain metastases to stereotactic radiosurgery
- (2016) Jack M. Qian et al. CANCER
- Techniques d’imagerie utilisées dans le diagnostic différentiel entre radionécrose cérébrale et rechute tumorale après irradiation en conditions stéréotaxiques de métastases cérébrales : revue de la littérature
- (2016) I. Menoux et al. Cancer Radiotherapie
- Ipilimumab Combined with Nivolumab: A Standard of Care for the Treatment of Advanced Melanoma?
- (2016) Matteo S. Carlino et al. CLINICAL CANCER RESEARCH
- Preclinical Comparison of Osimertinib with Other EGFR-TKIs in EGFR-Mutant NSCLC Brain Metastases Models, and Early Evidence of Clinical Brain Metastases Activity
- (2016) P. Ballard et al. CLINICAL CANCER RESEARCH
- Metastatic melanoma treatment: Combining old and new therapies
- (2016) Ryan J. Davey et al. CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
- Treatment of brain metastasis
- (2016) Roberta Rudà et al. CURRENT OPINION IN ONCOLOGY
- Imaging and Clinical Profile Following Concurrent Stereotactic Radiation and Immune Therapy for Melanoma Brain Metastases: Preliminary Results
- (2016) C. Shen et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Surgical Resection of Brain Metastases and the Risk of Leptomeningeal Recurrence in Patients Treated With Stereotactic Radiosurgery
- (2016) Matthew D. Johnson et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Single-Fraction Versus Multifraction (3 × 9 Gy) Stereotactic Radiosurgery for Large (>2 cm) Brain Metastases: A Comparative Analysis of Local Control and Risk of Radiation-Induced Brain Necrosis
- (2016) Giuseppe Minniti et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Effect of Radiosurgery Alone vs Radiosurgery With Whole Brain Radiation Therapy on Cognitive Function in Patients With 1 to 3 Brain Metastases
- (2016) Paul D. Brown et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Evaluating Cancer of the Central Nervous System Through Next-Generation Sequencing of Cerebrospinal Fluid
- (2016) Elena I. Pentsova et al. JOURNAL OF CLINICAL ONCOLOGY
- Translational Breast Cancer Research Consortium (TBCRC) 022: A Phase II Trial of Neratinib for Patients With Human Epidermal Growth Factor Receptor 2–Positive Breast Cancer and Brain Metastases
- (2016) Rachel A. Freedman et al. JOURNAL OF CLINICAL ONCOLOGY
- Multicenter Phase II Study of Whole-Body and Intracranial Activity With Ceritinib in Patients WithALK-Rearranged Non–Small-Cell Lung Cancer Previously Treated With Chemotherapy and Crizotinib: Results From ASCEND-2
- (2016) Lucio Crinò et al. JOURNAL OF CLINICAL ONCOLOGY
- Veliparib in combination with whole-brain radiation therapy for patients with brain metastases from non-small cell lung cancer: results of a randomized, global, placebo-controlled study
- (2016) Pierre Chabot et al. JOURNAL OF NEURO-ONCOLOGY
- Response of symptomatic brain metastases from HER-2 overexpressing breast cancer with T-DM1
- (2016) C. L. Gorter de Vries et al. JOURNAL OF NEURO-ONCOLOGY
- Comparing pre-operative stereotactic radiosurgery (SRS) to post-operative whole brain radiation therapy (WBRT) for resectable brain metastases: a multi-institutional analysis
- (2016) Kirtesh R. Patel et al. JOURNAL OF NEURO-ONCOLOGY
- P2.36: Nivolumab (nivo) in Patients (pts) With Advanced (adv) NSCLC and Central Nervous System (CNS) Metastases (mets)
- (2016) Jonathan W. Goldman et al. Journal of Thoracic Oncology
- First-Line Afatinib versus Chemotherapy in Patients with Non–Small Cell Lung Cancer and Common Epidermal Growth Factor Receptor Gene Mutations and Brain Metastases
- (2016) Martin Schuler et al. Journal of Thoracic Oncology
- Dexamethasone and supportive care with or without whole brain radiotherapy in treating patients with non-small cell lung cancer with brain metastases unsuitable for resection or stereotactic radiotherapy (QUARTZ): results from a phase 3, non-inferiority, randomised trial
- (2016) Paula Mulvenna et al. LANCET
- Activity and safety of brigatinib in ALK -rearranged non-small-cell lung cancer and other malignancies: a single-arm, open-label, phase 1/2 trial
- (2016) Scott N Gettinger et al. LANCET ONCOLOGY
- Pembrolizumab for patients with melanoma or non-small-cell lung cancer and untreated brain metastases: early analysis of a non-randomised, open-label, phase 2 trial
- (2016) Sarah B Goldberg et al. LANCET ONCOLOGY
- Dabrafenib plus trametinib in patients with previously treated BRAF V600E -mutant metastatic non-small cell lung cancer: an open-label, multicentre phase 2 trial
- (2016) David Planchard et al. LANCET ONCOLOGY
- Intracranial response to nivolumab in NSCLC patients with untreated or progressing CNS metastases
- (2016) Elizabeth Dudnik et al. LUNG CANCER
- DynamicO-(2-18F-fluoroethyl)-L-tyrosine positron emission tomography differentiates brain metastasis recurrence from radiation injury after radiotherapy
- (2016) Garry Ceccon et al. NEURO-ONCOLOGY
- Updates in the management of brain metastases
- (2016) Nils D. Arvold et al. NEURO-ONCOLOGY
- 215 Postoperative Stereotactic Radiosurgery vs Observation for Completely Resected Brain Metastases
- (2016) Ganesh Rao et al. NEUROSURGERY
- AZD3759, a BBB-penetrating EGFR inhibitor for the treatment of EGFR mutant NSCLC with CNS metastases
- (2016) Z. Yang et al. Science Translational Medicine
- New Therapeutic Opportunities Based on DNA Mismatch Repair and BRAF Status in Metastatic Colorectal Cancer
- (2016) Romain Cohen et al. Current Oncology Reports
- Local Tumor Treatment in Combination with Systemic Ipilimumab Immunotherapy Prolongs Overall Survival in Patients with Advanced Malignant Melanoma
- (2016) S. Theurich et al. Cancer Immunology Research
- Radiotherapy plus EGFR TKIs in non-small cell lung cancer patients with brain metastases: an update meta-analysis
- (2016) Tao Jiang et al. Cancer Medicine
- Embracing rejection: Immunologic trends in brain metastasis
- (2016) S. Harrison Farber et al. OncoImmunology
- Clinical outcomes of melanoma brain metastases treated with stereotactic radiation and anti-PD-1 therapy
- (2015) K. A. Ahmed et al. ANNALS OF ONCOLOGY
- Balancing bleeding in brain metastases
- (2015) L. B. Kreuziger BLOOD
- Detection of cerebrospinal fluid tumor cells and its clinical relevance in leptomeningeal metastasis of breast cancer
- (2015) Jin Sun Lee et al. BREAST CANCER RESEARCH AND TREATMENT
- Épidémiologie des lésions métastatiques cérébrales
- (2015) S. Taillibert et al. Cancer Radiotherapie
- Activity of T-DM1 in Her2-positive breast cancer brain metastases
- (2015) Rupert Bartsch et al. CLINICAL & EXPERIMENTAL METASTASIS
- Bevacizumab Preconditioning Followed by Etoposide and Cisplatin Is Highly Effective in Treating Brain Metastases of Breast Cancer Progressing from Whole-Brain Radiotherapy
- (2015) Y.-S. Lu et al. CLINICAL CANCER RESEARCH
- Diagnostic imaging of intracranial metastasis
- (2015) Stephen F. Kralik et al. CURRENT PROBLEMS IN CANCER
- Predictive role of BRAF mutations in patients with advanced colorectal cancer receiving cetuximab and panitumumab: A meta-analysis
- (2015) Filippo Pietrantonio et al. EUROPEAN JOURNAL OF CANCER
- Screening, resilience, patient navigation and information needs - key areas in cancer control
- (2015) D. Weller EUROPEAN JOURNAL OF CANCER CARE
- Differentiation of high-grade-astrocytomas from solitary-brain-metastases: Comparing diffusion kurtosis imaging and diffusion tensor imaging
- (2015) Yan Tan et al. EUROPEAN JOURNAL OF RADIOLOGY
- Testing for oncogenic molecular aberrations in cell-free DNA-based liquid biopsies in the clinic: are we there yet?
- (2015) Jiri Polivka et al. EXPERT REVIEW OF MOLECULAR DIAGNOSTICS
- Repeat Courses of Stereotactic Radiosurgery (SRS), Deferring Whole-Brain Irradiation, for New Brain Metastases After Initial SRS
- (2015) David B. Shultz et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Competing Risk Analysis of Neurologic versus Nonneurologic Death in Patients Undergoing Radiosurgical Salvage After Whole-Brain Radiation Therapy Failure: Who Actually Dies of Their Brain Metastases?
- (2015) John T. Lucas et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Phase 3 Trials of Stereotactic Radiosurgery With or Without Whole-Brain Radiation Therapy for 1 to 4 Brain Metastases: Individual Patient Data Meta-Analysis
- (2015) Arjun Sahgal et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Stereotactic Radiosurgery for Melanoma Brain Metastases in Patients Receiving Ipilimumab: Safety Profile and Efficacy of Combined Treatment
- (2015) Ana P. Kiess et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Leukoencephalopathy After Stereotactic Radiosurgery for Brain Metastases
- (2015) Daniel M. Trifiletti et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Clinical Experience With Crizotinib in Patients With Advanced ALK-Rearranged Non–Small-Cell Lung Cancer and Brain Metastases
- (2015) Daniel B. Costa et al. JOURNAL OF CLINICAL ONCOLOGY
- Donepezil for Irradiated Brain Tumor Survivors: A Phase III Randomized Placebo-Controlled Clinical Trial
- (2015) Stephen R. Rapp et al. JOURNAL OF CLINICAL ONCOLOGY
- NCCTG N0574 (Alliance): A phase III randomized trial of whole brain radiation therapy (WBRT) in addition to radiosurgery (SRS) in patients with 1 to 3 brain metastases.
- (2015) Paul D. Brown et al. JOURNAL OF CLINICAL ONCOLOGY
- Venous Thromboembolism Prophylaxis and Treatment in Patients With Cancer: American Society of Clinical Oncology Clinical Practice Guideline Update 2014
- (2015) Gary H. Lyman et al. JOURNAL OF CLINICAL ONCOLOGY
- Pooled Analysis of Long-Term Survival Data From Phase II and Phase III Trials of Ipilimumab in Unresectable or Metastatic Melanoma
- (2015) Dirk Schadendorf et al. JOURNAL OF CLINICAL ONCOLOGY
- Do Circulating Tumor Cells, Exosomes, and Circulating Tumor Nucleic Acids Have Clinical Utility?
- (2015) Bert Gold et al. JOURNAL OF MOLECULAR DIAGNOSTICS
- The brain metastatic niche
- (2015) Frank Winkler JOURNAL OF MOLECULAR MEDICINE-JMM
- Hypofractionated radiosurgery has a better safety profile than single fraction radiosurgery for large resected brain metastases
- (2015) Bree R. Eaton et al. JOURNAL OF NEURO-ONCOLOGY
- Veliparib in combination with whole brain radiation therapy in patients with brain metastases: results of a phase 1 study
- (2015) Minesh P. Mehta et al. JOURNAL OF NEURO-ONCOLOGY
- Long-term risk of radionecrosis and imaging changes after stereotactic radiosurgery for brain metastases
- (2015) Zachary A. Kohutek et al. JOURNAL OF NEURO-ONCOLOGY
- Impact of surgical methodology on the complication rate and functional outcome of patients with a single brain metastasis
- (2015) Akash J. Patel et al. JOURNAL OF NEUROSURGERY
- Integrated genomic and transcriptomic analysis of human brain metastases identifies alterations of potential clinical significance
- (2015) Jodi M Saunus et al. JOURNAL OF PATHOLOGY
- Dabrafenib and trametinib versus dabrafenib and placebo for Val600 BRAF-mutant melanoma: a multicentre, double-blind, phase 3 randomised controlled trial
- (2015) Georgina V Long et al. LANCET
- Afatinib alone or afatinib plus vinorelbine versus investigator's choice of treatment for HER2-positive breast cancer with progressive brain metastases after trastuzumab, lapatinib, or both (LUX-Breast 3): a randomised, open-label, multicentre, phase 2 trial
- (2015) Javier Cortés et al. LANCET ONCOLOGY
- Afatinib versus cisplatin-based chemotherapy for EGFR mutation-positive lung adenocarcinoma (LUX-Lung 3 and LUX-Lung 6): analysis of overall survival data from two randomised, phase 3 trials
- (2015) James Chih-Hsin Yang et al. LANCET ONCOLOGY
- Nivolumab versus chemotherapy in patients with advanced melanoma who progressed after anti-CTLA-4 treatment (CheckMate 037): a randomised, controlled, open-label, phase 3 trial
- (2015) Jeffrey S Weber et al. LANCET ONCOLOGY
- Tumor Progression in Patients Receiving Adjuvant Whole-Brain Radiotherapy vs Localized Radiotherapy After Surgical Resection of Brain Metastases
- (2015) Jason Hsieh et al. NEUROSURGERY
- Improved Overall Survival in Melanoma with Combined Dabrafenib and Trametinib
- (2015) Caroline Robert et al. NEW ENGLAND JOURNAL OF MEDICINE
- Nivolumab in Previously Untreated Melanoma without BRAF Mutation
- (2015) Caroline Robert et al. NEW ENGLAND JOURNAL OF MEDICINE
- Nivolumab versus Docetaxel in Advanced Squamous-Cell Non–Small-Cell Lung Cancer
- (2015) Julie Brahmer et al. NEW ENGLAND JOURNAL OF MEDICINE
- Pertuzumab, Trastuzumab, and Docetaxel in HER2-Positive Metastatic Breast Cancer
- (2015) Sandra M. Swain et al. NEW ENGLAND JOURNAL OF MEDICINE
- A Retrospective Evaluation of Vemurafenib as Treatment for BRAF-Mutant Melanoma Brain Metastases
- (2015) J. J. Harding et al. ONCOLOGIST
- Cerebrospinal fluid-derived circulating tumour DNA better represents the genomic alterations of brain tumours than plasma
- (2015) Leticia De Mattos-Arruda et al. Nature Communications
- Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets
- (2015) P. K. Brastianos et al. Cancer Discovery
- Next-Generation Sequencing of Stage IV Squamous Cell Lung Cancers Reveals an Association of PI3K Aberrations and Evidence of Clonal Heterogeneity in Patients with Brain Metastases
- (2015) P. K. Paik et al. Cancer Discovery
- Combination therapy with BRAF and MEK inhibitors for melanoma: latest evidence and place in therapy
- (2015) Zeynep Eroglu et al. Therapeutic Advances in Medical Oncology
- Stereotactic Radiosurgery With or Without Whole-Brain Radiotherapy for Brain Metastases
- (2015) Hidefumi Aoyama et al. JAMA Oncology
- Incidence of central nervous system metastases in patients with HER2-positive metastatic breast cancer treated with pertuzumab, trastuzumab, and docetaxel: results from the randomized phase III study CLEOPATRA
- (2014) S. M. Swain et al. ANNALS OF ONCOLOGY
- Three-year follow-up of advanced melanoma patients who received ipilimumab plus fotemustine in the Italian Network for Tumor Biotherapy (NIBIT)-M1 phase II study
- (2014) A. M. Di Giacomo et al. ANNALS OF ONCOLOGY
- ExtendedRASmutations and anti-EGFR monoclonal antibody survival benefit in metastatic colorectal cancer: a meta-analysis of randomized, controlled trials
- (2014) M. J. Sorich et al. ANNALS OF ONCOLOGY
- Everolimus plus exemestane for hormone-receptor-positive, human epidermal growth factor receptor-2-negative advanced breast cancer: overall survival results from BOLERO-2†
- (2014) M. Piccart et al. ANNALS OF ONCOLOGY
- Role of the Neural Niche in Brain Metastatic Cancer
- (2014) J. Termini et al. CANCER RESEARCH
- Indications and limitations of chemotherapy and targeted agents in non-small cell lung cancer brain metastases
- (2014) Stefan Zimmermann et al. CANCER TREATMENT REVIEWS
- Can diffusion-weighted imaging be used to differentiate brain abscess from other ring-enhancing brain lesions? A meta-analysis
- (2014) X.-X. Xu et al. CLINICAL RADIOLOGY
- BRAF alterations in brain tumours
- (2014) Anna Sophie Berghoff et al. CURRENT OPINION IN NEUROLOGY
- Napsin A is a useful marker for metastatic adenocarcinomas of pulmonary origin
- (2014) Moon-Young Kim et al. HISTOPATHOLOGY
- Molecular Biology of Brain Metastasis
- (2014) Konstantina Svokos et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Hippocampal-Avoidance Whole-Brain Radiation Therapy: A New Standard for Patients With Brain Metastases?
- (2014) John H. Suh JOURNAL OF CLINICAL ONCOLOGY
- Preservation of Memory With Conformal Avoidance of the Hippocampal Neural Stem-Cell Compartment During Whole-Brain Radiotherapy for Brain Metastases (RTOG 0933): A Phase II Multi-Institutional Trial
- (2014) Vinai Gondi et al. JOURNAL OF CLINICAL ONCOLOGY
- Sensitive Detection of EGFR Mutations in Cerebrospinal Fluid from Lung Adenocarcinoma Patients with Brain Metastases
- (2014) Haihong Yang et al. JOURNAL OF MOLECULAR DIAGNOSTICS
- LINAC-based stereotactic radiosurgery to the brain with concurrent vemurafenib for melanoma metastases
- (2014) Kamran A. Ahmed et al. JOURNAL OF NEURO-ONCOLOGY
- Intracranial control and radiographic changes with adjuvant radiation therapy for resected brain metastases: whole brain radiotherapy versus stereotactic radiosurgery alone
- (2014) Kirtesh R. Patel et al. JOURNAL OF NEURO-ONCOLOGY
- Fractionated stereotactic radiosurgery for patients with brain metastases
- (2014) Giuseppe Minniti et al. JOURNAL OF NEURO-ONCOLOGY
- Randomized Trial of Erlotinib Plus Whole-Brain Radiotherapy for NSCLC Patients With Multiple Brain Metastases
- (2014) Siow Ming Lee et al. JNCI-Journal of the National Cancer Institute
- Discoidin Domain Receptor 2 Signaling Networks and Therapy in Lung Cancer
- (2014) Leo S. Payne et al. Journal of Thoracic Oncology
- Safety and activity of alectinib against systemic disease and brain metastases in patients with crizotinib-resistant ALK-rearranged non-small-cell lung cancer (AF-002JG): results from the dose-finding portion of a phase 1/2 study
- (2014) Shirish M Gadgeel et al. LANCET ONCOLOGY
- Role of the endothelin axis in astrocyte- and endothelial cell-mediated chemoprotection of cancer cells
- (2014) Seung Wook Kim et al. NEURO-ONCOLOGY
- Ceritinib in ALK-Rearranged Non–Small-Cell Lung Cancer
- (2014) Alice T. Shaw et al. NEW ENGLAND JOURNAL OF MEDICINE
- Combined Vemurafenib and Cobimetinib in BRAF-Mutated Melanoma
- (2014) James Larkin et al. NEW ENGLAND JOURNAL OF MEDICINE
- The Value of Diffusion Tensor Imaging in Differentiating High-Grade Gliomas from Brain Metastases: A Systematic Review and Meta-Analysis
- (2014) Rui Jiang et al. PLoS One
- Human breast cancer metastases to the brain display GABAergic properties in the neural niche
- (2014) J. Neman et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- EGFR-TKI therapy for patients with brain metastases from non-small-cell lung cancer: a pooled analysis of published data
- (2014) Conghua Xie et al. OncoTargets and Therapy
- Systematic Review: Anti–Epidermal Growth Factor Receptor Treatment Effect Modification byKRASMutations in Advanced Colorectal Cancer
- (2013) Issa J. Dahabreh et al. ANNALS OF INTERNAL MEDICINE
- Molecular Profiling of Tumor Cells in Cerebrospinal Fluid and Matched Primary Tumors from Metastatic Breast Cancer Patients with Leptomeningeal Carcinomatosis
- (2013) M. J. M. Magbanua et al. CANCER RESEARCH
- A systematic review of trastuzumab and lapatinib in the treatment of women with brain metastases from HER2-positive breast cancer
- (2013) Pia Bükmann Larsen et al. CANCER TREATMENT REVIEWS
- A systematic review of dual targeting in HER2-positive breast cancer
- (2013) Iben Kümler et al. CANCER TREATMENT REVIEWS
- Targeting the MET gene for the treatment of non-small-cell lung cancer
- (2013) F. Gelsomino et al. CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
- Targeted Therapies in Brain Metastases
- (2013) Nancy U. Lin Current Treatment Options in Neurology
- Vemurafenib in patients with BRAFV600 mutation-positive melanoma with symptomatic brain metastases: Final results of an open-label pilot study
- (2013) Reinhard Dummer et al. EUROPEAN JOURNAL OF CANCER
- A Phase 3 Trial of Whole Brain Radiation Therapy and Stereotactic Radiosurgery Alone Versus WBRT and SRS With Temozolomide or Erlotinib for Non-Small Cell Lung Cancer and 1 to 3 Brain Metastases: Radiation Therapy Oncology Group 0320
- (2013) Paul W. Sperduto et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- The Abscopal Effect Associated With a Systemic Anti-melanoma Immune Response
- (2013) Emily F. Stamell et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Risk of Leptomeningeal Disease in Patients Treated With Stereotactic Radiosurgery Targeting the Postoperative Resection Cavity for Brain Metastases
- (2013) Banu Atalar et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Salvage Radiosurgery for Brain Metastases: Prognostic Factors to Consider in Patient Selection
- (2013) Goldie Kurtz et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Phase II Trial of Erlotinib Plus Concurrent Whole-Brain Radiation Therapy for Patients With Brain Metastases From Non–Small-Cell Lung Cancer
- (2013) James W. Welsh et al. JOURNAL OF CLINICAL ONCOLOGY
- Clinical outcomes of patients treated with a second course of stereotactic radiosurgery for locally or regionally recurrent brain metastases after prior stereotactic radiosurgery
- (2013) Daniel H. Kim et al. JOURNAL OF NEURO-ONCOLOGY
- Vemurafenib and radiation therapy in melanoma brain metastases
- (2013) Ashwatha Narayana et al. JOURNAL OF NEURO-ONCOLOGY
- CNS metastases in non-small-cell lung cancer: Current role of EGFR-TKI therapy and future perspectives
- (2013) Lars Arne Berger et al. LUNG CANCER
- ALK gene translocations and amplifications in brain metastases of non-small cell lung cancer
- (2013) Matthias Preusser et al. LUNG CANCER
- High rate of FGFR1 amplifications in brain metastases of squamous and non-squamous lung cancer
- (2013) Matthias Preusser et al. LUNG CANCER
- Ipilimumab in melanoma with limited brain metastases treated with stereotactic radiosurgery
- (2013) Maya Mathew et al. MELANOMA RESEARCH
- Bevacizumab as a treatment for radiation necrosis of brain metastases post stereotactic radiosurgery
- (2013) Dustin Boothe et al. NEURO-ONCOLOGY
- Memantine for the prevention of cognitive dysfunction in patients receiving whole-brain radiotherapy: a randomized, double-blind, placebo-controlled trial
- (2013) P. D. Brown et al. NEURO-ONCOLOGY
- Safety and Tumor Responses with Lambrolizumab (Anti–PD-1) in Melanoma
- (2013) Omid Hamid et al. NEW ENGLAND JOURNAL OF MEDICINE
- Population-based outcomes of boost versus salvage radiosurgery for brain metastases after whole brain radiotherapy
- (2013) Fred Hsu et al. RADIOTHERAPY AND ONCOLOGY
- In Search of the Ideal Immunopanel to Distinguish Metastatic Mammary Carcinoma From Primary Lung Carcinoma
- (2013) Kathy R. Kawaguchi et al. APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY
- Concurrent Radiotherapy and Ipilimumab Immunotherapy for Patients with Melanoma
- (2013) C. A. Barker et al. Cancer Immunology Research
- Ipilimumab and radiation therapy for melanoma brain metastases
- (2013) Ann W. Silk et al. Cancer Medicine
- Brain metastases: pathobiology and emerging targeted therapies
- (2012) Matthias Preusser et al. ACTA NEUROPATHOLOGICA
- Leukoencephalopathy after whole-brain radiation therapy plus radiosurgery versus radiosurgery alone for metastatic lung cancer
- (2012) Edward A. Monaco et al. CANCER
- Therapeutic Implications of KIT in Melanoma
- (2012) Michael A. Postow et al. CANCER JOURNAL
- Cerebrospinal Fluid Concentrations of Gefitinib in Patients With Lung Adenocarcinoma
- (2012) Jing Zhao et al. Clinical Lung Cancer
- Brain metastasis
- (2012) Matthias Preusser et al. CURRENT OPINION IN NEUROLOGY
- Effect of cancer therapy on neural stem cells
- (2012) Erin Gibson et al. CURRENT OPINION IN ONCOLOGY
- Targeted therapy in brain metastasis
- (2012) Riccardo Soffietti et al. CURRENT OPINION IN ONCOLOGY
- Brain metastases as the first symptom of lung cancer: a clinical study from an Asian medical center
- (2012) Jia Jin et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- ROS1 Rearrangements Define a Unique Molecular Class of Lung Cancers
- (2012) Kristin Bergethon et al. JOURNAL OF CLINICAL ONCOLOGY
- A European Organisation for Research and Treatment of Cancer Phase III Trial of Adjuvant Whole-Brain Radiotherapy Versus Observation in Patients With One to Three Brain Metastases From Solid Tumors After Surgical Resection or Radiosurgery: Quality-of-Life Results
- (2012) Riccardo Soffietti et al. JOURNAL OF CLINICAL ONCOLOGY
- EGFR mutation status in brain metastases of non-small cell lung carcinoma
- (2012) Fanny Burel-Vandenbos et al. JOURNAL OF NEURO-ONCOLOGY
- Radiosurgery for melanoma brain metastases in the ipilimumab era and the possibility of longer survival
- (2012) Jonathan P. S. Knisely et al. JOURNAL OF NEUROSURGERY
- Diagnostic Performance of 18F-FET PET in Newly Diagnosed Cerebral Lesions Suggestive of Glioma
- (2012) M. Rapp et al. JOURNAL OF NUCLEAR MEDICINE
- Efficacy and safety of everolimus for subependymal giant cell astrocytomas associated with tuberous sclerosis complex (EXIST-1): a multicentre, randomised, placebo-controlled phase 3 trial
- (2012) David Neal Franz et al. LANCET
- Ipilimumab in patients with melanoma and brain metastases: an open-label, phase 2 trial
- (2012) Kim Margolin et al. LANCET ONCOLOGY
- Dabrafenib in patients with Val600Glu or Val600Lys BRAF-mutant melanoma metastatic to the brain (BREAK-MB): a multicentre, open-label, phase 2 trial
- (2012) Georgina V Long et al. LANCET ONCOLOGY
- Lapatinib plus capecitabine in patients with previously untreated brain metastases from HER2-positive metastatic breast cancer (LANDSCAPE): a single-group phase 2 study
- (2012) Thomas Bachelot et al. LANCET ONCOLOGY
- Combined Therapy with Mutant-Selective EGFR Inhibitor and Met Kinase Inhibitor for Overcoming Erlotinib Resistance in EGFR-Mutant Lung Cancer
- (2012) T. Nakagawa et al. MOLECULAR CANCER THERAPEUTICS
- Toward determining the lifetime occurrence of metastatic brain tumors estimated from 2007 United States cancer incidence data
- (2012) Faith G. Davis et al. NEURO-ONCOLOGY
- Combined BRAF and MEK Inhibition in Melanoma with BRAF V600 Mutations
- (2012) Keith T. Flaherty et al. NEW ENGLAND JOURNAL OF MEDICINE
- Safety, Activity, and Immune Correlates of Anti–PD-1 Antibody in Cancer
- (2012) Suzanne L. Topalian et al. NEW ENGLAND JOURNAL OF MEDICINE
- Iodine-125 brachytherapy for brain tumours - a review
- (2012) Silke B Schwarz et al. Radiation Oncology
- Impact of BRAF mutation and microsatellite instability on the pattern of metastatic spread and prognosis in metastatic colorectal cancer
- (2011) Ben Tran et al. CANCER
- A meta-analysis evaluating stereotactic radiosurgery, whole-brain radiotherapy, or both for patients presenting with a limited number of brain metastases
- (2011) May Tsao et al. CANCER
- Expression of antigen processing and presenting molecules in brain metastasis of breast cancer
- (2011) Yan Liu et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Tissue confirmation of disease recurrence in breast cancer patients: Pooled analysis of multi-centre, multi-disciplinary prospective studies
- (2011) Eitan Amir et al. CANCER TREATMENT REVIEWS
- Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in the Treatment of Epidermal Growth Factor Receptor-Mutant Non-Small Cell Lung Cancer Metastatic to the Brain
- (2011) M. Jamal-Hanjani et al. CLINICAL CANCER RESEARCH
- Phase I Clinical Trial Outcomes in 93 Patients with Brain Metastases: The MD Anderson Cancer Center Experience
- (2011) A. M. Tsimberidou et al. CLINICAL CANCER RESEARCH
- Prognostic Factors for Survival in Patients Treated With Stereotactic Radiosurgery for Recurrent Brain Metastases After Prior Whole Brain Radiotherapy
- (2011) Jorge A. Caballero et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- CSF Concentration of the Anaplastic Lymphoma Kinase Inhibitor Crizotinib
- (2011) Daniel B. Costa et al. JOURNAL OF CLINICAL ONCOLOGY
- Safety and clinical activity of ipilimumab in melanoma patients with brain metastases
- (2011) Jeffrey S. Weber et al. MELANOMA RESEARCH
- Ipilimumab plus Dacarbazine for Previously Untreated Metastatic Melanoma
- (2011) Caroline Robert et al. NEW ENGLAND JOURNAL OF MEDICINE
- Proton magnetic resonance spectroscopy in the distinction of high-grade cerebral gliomas from single metastatic brain tumors
- (2010) Andres Server et al. ACTA RADIOLOGICA
- Prognostic factors for survival in melanoma patients with brain metastases
- (2010) Michael A. Davies et al. CANCER
- Macrophage Diversity Enhances Tumor Progression and Metastasis
- (2010) Bin-Zhi Qian et al. CELL
- Interaction between lung cancer cells and astrocytes via specific inflammatory cytokines in the microenvironment of brain metastasis
- (2010) Toshihiro Seike et al. CLINICAL & EXPERIMENTAL METASTASIS
- Brain metastases from lung cancer responding to erlotinib: the importance of EGFR mutation
- (2010) R. Porta et al. EUROPEAN RESPIRATORY JOURNAL
- Hallmarks of cancer: Interactions with the tumor stroma
- (2010) Kristian Pietras et al. EXPERIMENTAL CELL RESEARCH
- Intracranial Metastatic Disease Spares the Limbic Circuit: A Review of 697 Metastatic Lesions in 107 Patients
- (2010) James C. Marsh et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Adjuvant Whole-Brain Radiotherapy Versus Observation After Radiosurgery or Surgical Resection of One to Three Cerebral Metastases: Results of the EORTC 22952-26001 Study
- (2010) Martin Kocher et al. JOURNAL OF CLINICAL ONCOLOGY
- Stereotactic radiosurgery as primary and salvage treatment for brain metastases from breast cancer
- (2010) Douglas Kondziolka et al. JOURNAL OF NEUROSURGERY
- Activation of MET by Gene Amplification or by Splice Mutations Deleting the Juxtamembrane Domain in Primary Resected Lung Cancers
- (2010) Ryoichi Onozato et al. Journal of Thoracic Oncology
- The Molecular Pathobiology of Metastasis to the Brain: A Review
- (2010) Kara D. Beasley et al. NEUROSURGERY CLINICS OF NORTH AMERICA
- Improved Survival with Ipilimumab in Patients with Metastatic Melanoma
- (2010) F. Stephen Hodi et al. NEW ENGLAND JOURNAL OF MEDICINE
- EMT, the cytoskeleton, and cancer cell invasion
- (2009) Mahmut Yilmaz et al. CANCER AND METASTASIS REVIEWS
- Mechanics, malignancy, and metastasis: The force journey of a tumor cell
- (2009) Sanjay Kumar et al. CANCER AND METASTASIS REVIEWS
- Epithelial-Mesenchymal Transitions in Development and Disease
- (2009) Jean Paul Thiery et al. CELL
- Intracerebral metastasis showing restricted diffusion: Correlation with histopathologic findings
- (2009) G. Duygulu et al. EUROPEAN JOURNAL OF RADIOLOGY
- Diagnosis-Specific Prognostic Factors, Indexes, and Treatment Outcomes for Patients With Newly Diagnosed Brain Metastases: A Multi-Institutional Analysis of 4,259 Patients
- (2009) Paul W. Sperduto et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Antiepileptics in brain metastases: safety, efficacy and impact on life expectancy
- (2009) M. Maschio et al. JOURNAL OF NEURO-ONCOLOGY
- The role of chemotherapy in the management of newly diagnosed brain metastases: a systematic review and evidence-based clinical practice guideline
- (2009) Minesh P. Mehta et al. JOURNAL OF NEURO-ONCOLOGY
- The role of prophylactic anticonvulsants in the management of brain metastases: a systematic review and evidence-based clinical practice guideline
- (2009) Tom Mikkelsen et al. JOURNAL OF NEURO-ONCOLOGY
- The role of steroids in the management of brain metastases: a systematic review and evidence-based clinical practice guideline
- (2009) Timothy C. Ryken et al. JOURNAL OF NEURO-ONCOLOGY
- Stereotactic radiosurgery for metastatic brain tumors: a comprehensive review of complications
- (2009) Brian J. Williams et al. JOURNAL OF NEUROSURGERY
- Neurocognition in patients with brain metastases treated with radiosurgery or radiosurgery plus whole-brain irradiation: a randomised controlled trial
- (2009) Eric L Chang et al. LANCET ONCOLOGY
- Salvage stereotactic radiosurgery effectively treats recurrences from whole-brain radiation therapy
- (2008) Samuel T. Chao et al. CANCER
- Temozolomide, thalidomide, and whole brain radiation therapy for patients with brain metastasis from metastatic melanoma
- (2008) Michael B. Atkins et al. CANCER
- Brain metastases: current management and new developments
- (2008) Riccardo Soffietti et al. CURRENT OPINION IN ONCOLOGY
- Whole brain radiotherapy plus stereotactic radiosurgery (WBRT+SRS) versus surgery plus whole brain radiotherapy (OP+WBRT) for 1–3 brain metastases: Results of a matched pair analysis
- (2008) Dirk Rades et al. EUROPEAN JOURNAL OF CANCER
- Motexafin Gadolinium Combined With Prompt Whole Brain Radiotherapy Prolongs Time to Neurologic Progression in Non–Small-Cell Lung Cancer Patients With Brain Metastases: Results of a Phase III Trial
- (2008) Minesh P. Mehta et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Major Response to Imatinib Mesylate in KIT-Mutated Melanoma
- (2008) F. Stephen Hodi et al. JOURNAL OF CLINICAL ONCOLOGY
- Phase II Trial of Lapatinib for Brain Metastases in Patients With Human Epidermal Growth Factor Receptor 2–Positive Breast Cancer
- (2008) Nancy U. Lin et al. JOURNAL OF CLINICAL ONCOLOGY
- Comparative risk of leptomeningeal disease after resection or stereotactic radiosurgery for solid tumor metastasis to the posterior fossa
- (2008) Dima Suki et al. JOURNAL OF NEUROSURGERY
- A New Prognostic Index and Comparison to Three Other Indices for Patients With Brain Metastases: An Analysis of 1,960 Patients in the RTOG Database
- (2007) Paul W. Sperduto et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now