Brainstem tau pathology in Alzheimer’s disease is characterized by increase of three repeat tau and independent of amyloid β

Cryo-EM structures of tau filaments from Alzheimer’s disease

(2017) Anthony W. P. Fitzpatrick et al.   NATURE

The Brainstem Tau Cytoskeletal Pathology of Alzheimer’s Disease: A Brief Historical Overview and Description of its Anatomical Distribution Pattern, Evolutional Features, Pathogenetic and Clinical Relevance

(2016) Udo Rüb et al.   Current Alzheimer Research

Biochemical classification of tauopathies by immunoblot, protein sequence and mass spectrometric analyses of sarkosyl-insoluble and trypsin-resistant tau

(2015) Sayuri Taniguchi-Watanabe et al.   ACTA NEUROPATHOLOGICA

PART is part of Alzheimer disease

(2015) Charles Duyckaerts et al.   ACTA NEUROPATHOLOGICA

The preclinical phase of the pathological process underlying sporadic Alzheimer’s disease

(2015) Heiko Braak et al.   BRAIN

Primary age-related tauopathy (PART): a common pathology associated with human aging

(2014) John F. Crary et al.   ACTA NEUROPATHOLOGICA

A glutamatergic reward input from the dorsal raphe to ventral tegmental area dopamine neurons

(2014) Jia Qi et al.   Nature Communications

Dendritic retraction, but not atrophy, is consistent in amyotrophic lateral sclerosis-comparison between Onuf’s neurons and other sacral motor neurons-

(2014) Takahiro Takeda et al.   Acta Neuropathologica Communications

Ultrastructural differences in pretangles between Alzheimer disease and corticobasal degeneration revealed by comparative light and electron microscopy

(2014) Shinsui Tatsumi et al.   Acta Neuropathologica Communications

3R and 4R tau isoforms in paired helical filaments in Alzheimer’s disease

(2013) Masato Hasegawa et al.   ACTA NEUROPATHOLOGICA

Isoform transition from four-repeat to three-repeat tau underlies dendrosomatic and regional progression of neurofibrillary pathology

(2013) Makoto Hara et al.   ACTA NEUROPATHOLOGICA

Variation in tau isoform expression in different brain regions and disease states

(2013) Elisa Majounie et al.   NEUROBIOLOGY OF AGING

Extensive deamidation at asparagine residue 279 accounts for weak immunoreactivity of tau with RD4 antibody in Alzheimer’s disease brain

(2013) Ayaho Dan et al.   Acta Neuropathologica Communications

Atomic Identification of Fluorescent Q-Dots on Tau-Positive Fibrils in 3D-Reconstructed Pick Bodies

(2012) Miho Uematsu et al.   AMERICAN JOURNAL OF PATHOLOGY

Variations in Filament Conformation Dictate Seeding Barrier between Three- and Four-Repeat Tau

(2011) Paul D. Dinkel et al.   BIOCHEMISTRY

Pale Neurites, Premature α-Synuclein Aggregates with Centripetal Extension from Axon Collaterals

(2011) Toshiro Kanazawa et al.   BRAIN PATHOLOGY

Tangle evolution linked to differential 3- and 4-repeat tau isoform deposition: a double immunofluorolabeling study using two monoclonal antibodies

(2011) Toshiki Uchihara et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Correlations between cortical and subcortical tau pathology

(2011) J. Attems et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Soluble amyloid  -protein dimers isolated from Alzheimer cortex directly induce Tau hyperphosphorylation and neuritic degeneration

(2011) M. Jin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The pathological process underlying Alzheimer’s disease in individuals under thirty

(2010) Heiko Braak et al.   ACTA NEUROPATHOLOGICA

Specific Detection of Pathological Three-repeat Tau after Pretreatment with Potassium Permanganate and Oxalic Acid in PSP/CBD Brains

(2010) Toshiki Uchihara et al.   BRAIN PATHOLOGY

A  Oligomers Cause Localized Ca2+ Elevation, Missorting of Endogenous Tau into Dendrites, Tau Phosphorylation, and Destruction of Microtubules and Spines

(2010) H. Zempel et al.   JOURNAL OF NEUROSCIENCE

Three Repeat Isoforms of Tau Inhibit Assembly of Four Repeat Tau Filaments

(2010) Stephanie J. Adams et al.   PLoS One

Hippocampal tau pathology is related to neuroanatomical connections: an ageing population-based study

(2009) G. Lace et al.   BRAIN

The dorsal raphe nucleus shows phospho-tau neurofibrillary changes before the transentorhinal region in Alzheimer's disease. A precocious onset?

(2009) L. T. Grinberg et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Does Alzheimer's disease begin in the brainstem?

(2009) G. Simic et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Functional Neuroanatomy of the Noradrenergic Locus Coeruleus: Its Roles in the Regulation of Arousal and Autonomic Function Part I: Principles of Functional Organisation

(2008) E. Samuels et al.   Current Neuropharmacology