Emerging properties of hydrogels in tissue engineering

Combinatorial hydrogels with biochemical gradients for screening 3D cellular microenvironments

(2018) Sebastián L. Vega et al.   Nature Communications

Mechanical confinement regulates cartilage matrix formation by chondrocytes

(2017) Hong-pyo Lee et al.   NATURE MATERIALS

Advances in engineering hydrogels

(2017) Yu Shrike Zhang et al.   SCIENCE

Matrix degradability controls multicellularity of 3D cell migration

(2017) Britta Trappmann et al.   Nature Communications

BMP2-modified injectable hydrogel for osteogenic differentiation of human periodontal ligament stem cells

(2017) Seung Hun Park et al.   Scientific Reports

Defined three-dimensional microenvironments boost induction of pluripotency

(2016) Massimiliano Caiazzo et al.   NATURE MATERIALS

A practical guide to hydrogels for cell culture

(2016) Steven R Caliari et al.   NATURE METHODS

Strain-enhanced stress relaxation impacts nonlinear elasticity in collagen gels

(2016) Sungmin Nam et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The design of reversible hydrogels to capture extracellular matrix dynamics

(2016) Adrianne M. Rosales et al.   Nature Reviews Materials

Designing hydrogels for controlled drug delivery

(2016) Jianyu Li et al.   Nature Reviews Materials

Microenvironment complexity and matrix stiffness regulate breast cancer cell activity in a 3D in vitro model

(2016) Marta Cavo et al.   Scientific Reports

Beta Hairpin Peptide Hydrogels as an Injectable Solid Vehicle for Neurotrophic Growth Factor Delivery

(2015) Stephan Lindsey et al.   BIOMACROMOLECULES

Synthesis, properties, and biomedical applications of gelatin methacryloyl (GelMA) hydrogels

(2015) Kan Yue et al.   BIOMATERIALS

Engineering the hematopoietic stem cell niche: Frontiers in biomaterial science

(2015) Ji Sun Choi et al.   Biotechnology Journal

Cell-mediated fibre recruitment drives extracellular matrix mechanosensing in engineered fibrillar microenvironments

(2015) Brendon M. Baker et al.   NATURE MATERIALS

Hydrogels with tunable stress relaxation regulate stem cell fate and activity

(2015) Ovijit Chaudhuri et al.   NATURE MATERIALS

Substrate stress relaxation regulates cell spreading

(2015) Ovijit Chaudhuri et al.   Nature Communications

Engineering the hematopoietic stem cell niche: Frontiers in biomaterial science

(2015) Ji Sun Choi et al.   Biotechnology Journal

In situ gelling pH- and temperature-sensitive biodegradable block copolymer hydrogels for drug delivery

(2014) Narendra K. Singh et al.   JOURNAL OF CONTROLLED RELEASE

Interplay of matrix stiffness and protein tethering in stem cell differentiation

(2014) Jessica H. Wen et al.   NATURE MATERIALS

Tuning mechanical performance of poly(ethylene glycol) and agarose interpenetrating network hydrogels for cartilage tissue engineering

(2013) Deena A. Rennerfeldt et al.   BIOMATERIALS

Degradation-mediated cellular traction directs stem cell fate in covalently crosslinked three-dimensional hydrogels

(2013) Sudhir Khetan et al.   NATURE MATERIALS

Extracellular-matrix tethering regulates stem-cell fate

(2012) Britta Trappmann et al.   NATURE MATERIALS

Stiffening hydrogels to probe short- and long-term cellular responses to dynamic mechanics

(2012) Murat Guvendiren et al.   Nature Communications

Enhanced MSC chondrogenesis following delivery of TGF-β3 from alginate microspheres within hyaluronic acid hydrogels in vitro and in vivo

(2011) Liming Bian et al.   BIOMATERIALS

Harnessing traction-mediated manipulation of the cell/matrix interface to control stem-cell fate

(2010) Nathaniel Huebsch et al.   NATURE MATERIALS

The effect of substrate stiffness on adult neural stem cell behavior

(2009) Nic D. Leipzig et al.   BIOMATERIALS

Photodegradable Hydrogels for Dynamic Tuning of Physical and Chemical Properties

(2009) April M. Kloxin et al.   SCIENCE

Interactions between integrin ligand density and cytoskeletal integrity regulate BMSC chondrogenesis

(2008) John T. Connelly et al.   JOURNAL OF CELLULAR PHYSIOLOGY