Efficacy of metformin in combination with immune checkpoint inhibitors (anti-PD-1/anti-CTLA-4) in metastatic malignant melanoma

Mechanisms of resistance to immune checkpoint inhibitors

(2018) Russell W Jenkins et al.   BRITISH JOURNAL OF CANCER

Phenformin Inhibits Myeloid-Derived Suppressor Cells and Enhances the Anti-Tumor Activity of PD-1 Blockade in Melanoma

(2017) Sun Hye Kim et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Metformin monotherapy in melanoma: a pilot, open-label, prospective, and multicentric study indicates no benefit

(2017) Henri Montaudié et al.   Pigment Cell & Melanoma Research

Effects of commonly used chronic medications on the outcomes of ipilimumab therapy in patients with metastatic melanoma

(2016) Jarrett J. Failing et al.   MELANOMA RESEARCH

Efficacy of PD-1 Blockade Is Potentiated by Metformin-Induced Reduction of Tumor Hypoxia

(2016) Nicole E. Scharping et al.   Cancer Immunology Research

Optimal therapy of type 2 diabetes: a controversial challenge

(2016) Angela Dardano et al.   Aging-US

Combining BRAFV600Einhibition with modulators of the mitochondrial bioenergy metabolism to overcome drug resistance in metastatic melanoma

(2015) Elisabeth Livingstone et al.   EXPERIMENTAL DERMATOLOGY

Myeloid-derived suppressor cells in the tumor microenvironment: expect the unexpected

(2015) Douglas Marvel et al.   JOURNAL OF CLINICAL INVESTIGATION

Impact of NRAS Mutations for Patients with Advanced Melanoma Treated with Immune Therapies

(2015) D. B. Johnson et al.   Cancer Immunology Research

Is it time to test biguanide metformin in the treatment of melanoma?

(2014) Michael Cerezo et al.   Pigment Cell & Melanoma Research

Metformin Blocks Melanoma Invasion and Metastasis Development in AMPK/p53-Dependent Manner

(2013) M. Cerezo et al.   MOLECULAR CANCER THERAPEUTICS

Metformin Therapy and Risk of Cancer in Patients with Type 2 Diabetes: Systematic Review

(2013) Monica Franciosi et al.   PLoS One

Metformin kills and radiosensitizes cancer cells and preferentially kills cancer stem cells

(2012) Chang W. Song et al.   Scientific Reports

Mechanisms of Resistance to RAF Inhibitors in Melanoma

(2011) Andrew E. Aplin et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Metformin inhibits melanoma development through autophagy and apoptosis mechanisms

(2011) T Tomic et al.   Cell Death & Disease

Metformin blocks the stimulative effect of a high-energy diet on colon carcinoma growth in vivo and is associated with reduced expression of fatty acid synthase

(2010) Carolyn Algire et al.   ENDOCRINE-RELATED CANCER

Epithelial–mesenchymal transition in the skin

(2010) Motonobu Nakamura et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Metformin in Cancer Therapy: A New Perspective for an Old Antidiabetic Drug?

(2010) I. Ben Sahra et al.   MOLECULAR CANCER THERAPEUTICS

32 INVITED New response evaluation criteria in solid tumors: revised RECIST guideline version 1.1

(2008) E. Eisenhauer et al.   EJC SUPPLEMENTS

AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint

(2008) Dana M. Gwinn et al.   MOLECULAR CELL