Growing old, yet staying young: The role of telomeres in bats’ exceptional longevity

Rare catastrophic events drive population dynamics in a bat species with negligible senescence

(2017) Toni Fleischer et al.   Scientific Reports

Blood miRNomes and transcriptomes reveal novel longevity mechanisms in the long-lived bat, Myotis myotis

(2016) Zixia Huang et al.   BMC GENOMICS

Shelterin

(2016) Isabelle Schmutz et al.   CURRENT BIOLOGY

Wing Membrane Biopsies for Bat Cytogenetics: Finding of 2n = 54 in Irish Rhinolophushipposideros (Rhinolophidae, Chiroptera, Mammalia) Supports Two Geographically Separated Chromosomal Variants in Europe

(2016) Joanna Kacprzyk et al.   CYTOGENETIC AND GENOME RESEARCH

Chromosome-scale shotgun assembly using an in vitro method for long-range linkage

(2016) Nicholas H. Putnam et al.   GENOME RESEARCH

The Genomes of Two Bat Species with Long Constant Frequency Echolocation Calls

(2016) Dong Dong et al.   MOLECULAR BIOLOGY AND EVOLUTION

Roles of telomeres and telomerase in cancer, and advances in telomerase-targeted therapies

(2016) Mohammad A. Jafri et al.   Genome Medicine

Frontal Cortex Transcriptome Analysis of Mice Exposed to Electronic Cigarettes During Early Life Stages

(2016) Dana Lauterstein et al.   International Journal of Environmental Research and Public Health

The transcriptome of the bowhead whale Balaena mysticetus reveals adaptations of the longest-lived mammal

(2016) Inge Seim et al.   Aging-US

DNA repair in species with extreme lifespan differences

(2015) Sheila L MacRae et al.   Aging-US

Long-lived species have improved proteostasis compared to phylogenetically-related shorter-lived species

(2015) Harrison Pride et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Telomeres shorten more slowly in slow-aging wild animals than in fast-aging ones

(2015) Ben Dantzer et al.   EXPERIMENTAL GERONTOLOGY

A nonlethal sampling method to obtain, generate and assemble whole blood transcriptomes from small, wild mammals

(2015) Zixia Huang et al.   Molecular Ecology Resources

Integrative network analysis reveals molecular mechanisms of blood pressure regulation

(2015) T. Huan et al.   Molecular Systems Biology

Senataxin suppresses the antiviral transcriptional response and controls viral biogenesis

(2015) Matthew S Miller et al.   NATURE IMMUNOLOGY

Characterization of global loss of imprinting in fetal overgrowth syndrome induced by assisted reproduction

(2015) Zhiyuan Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification and Characterization of Circular RNAs As a New Class of Putative Biomarkers in Human Blood

(2015) Sebastian Memczak et al.   PLoS One

Comparative transcriptomic analysis to identify differentially expressed genes in fat tissue of adult Berkshire and Jeju Native Pig using RNA-seq

(2014) Simrinder Singh Sodhi et al.   MOLECULAR BIOLOGY REPORTS

Sailfish enables alignment-free isoform quantification from RNA-seq reads using lightweight algorithms

(2014) Rob Patro et al.   NATURE BIOTECHNOLOGY

ATM regulates NF-κB-dependent immediate-early genes via RelA Ser 276 phosphorylation coupled to CDK9 promoter recruitment

(2014) Ling Fang et al.   NUCLEIC ACIDS RESEARCH

STRING v10: protein–protein interaction networks, integrated over the tree of life

(2014) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Ecology and mode-of-life explain lifespan variation in birds and mammals

(2014) K. Healy et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

The Scientific Quest for Lasting Youth: Prospects for Curing Aging

(2014) João Pedro de Magalhães   REJUVENATION RESEARCH

A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages

(2014) Ying Yu et al.   Nature Communications

Measuring telomere length and telomere dynamics in evolutionary biology and ecology

(2014) Daniel H. Nussey et al.   Methods in Ecology and Evolution

MicroRNAs linking inflamm-aging, cellular senescence and cancer

(2013) Fabiola Olivieri et al.   AGEING RESEARCH REVIEWS

Molecular adaptation of telomere associated genes in mammals

(2013) Claire C Morgan et al.   BMC EVOLUTIONARY BIOLOGY

Expansion of ruminant-specific microRNAs shapes target gene expression divergence between ruminant and non-ruminant species

(2013) Hua Bao et al.   BMC GENOMICS

The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

Analysis of the Human Tissue-specific Expression by Genome-wide Integration of Transcriptomics and Antibody-based Proteomics

(2013) Linn Fagerberg et al.   MOLECULAR & CELLULAR PROTEOMICS

MAFFT Multiple Sequence Alignment Software Version 7: Improvements in Performance and Usability

(2013) K. Katoh et al.   MOLECULAR BIOLOGY AND EVOLUTION

Molecular phylogenetic reconstructions identify East Asia as the cradle for the evolution of the cosmopolitan genus Myotis (Mammalia, Chiroptera)

(2013) Manuel Ruedi et al.   MOLECULAR PHYLOGENETICS AND EVOLUTION

Genomic analyses identify distinct patterns of selection in domesticated pigs and Tibetan wild boars

(2013) Mingzhou Li et al.   NATURE GENETICS

Omics technologies and the study of human ageing

(2013) Ana M. Valdes et al.   NATURE REVIEWS GENETICS

Genome analysis reveals insights into physiology and longevity of the Brandt’s bat Myotis brandtii

(2013) Inge Seim et al.   Nature Communications

Senataxin Plays an Essential Role with DNA Damage Response Proteins in Meiotic Recombination and Gene Silencing

(2013) Olivier J. Becherel et al.   PLoS Genetics

Aging, Cellular Senescence, and Cancer

(2012) Judith Campisi   Annual Review of Physiology

Snakemake--a scalable bioinformatics workflow engine

(2012) J. Koster et al.   BIOINFORMATICS

Senataxin Associates with Replication Forks to Protect Fork Integrity across RNA-Polymerase-II-Transcribed Genes

(2012) Amaya Alzu et al.   CELL

A Critical Assessment of Storytelling: Gene Ontology Categories and the Importance of Validating Genomic Scans

(2012) Pavlos Pavlidis et al.   MOLECULAR BIOLOGY AND EVOLUTION

The roles of WRN and BLM RecQ helicases in the Alternative Lengthening of Telomeres

(2012) Aaron Mendez-Bermudez et al.   NUCLEIC ACIDS RESEARCH

Human Ageing Genomic Resources: Integrated databases and tools for the biology and genetics of ageing

(2012) Robi Tacutu et al.   NUCLEIC ACIDS RESEARCH

Comparative Analysis of Bat Genomes Provides Insight into the Evolution of Flight and Immunity

(2012) G. Zhang et al.   SCIENCE

Birds and longevity: Does flight driven aerobicity provide an oxidative sink?

(2011) Anthony J.R. Hickey et al.   AGEING RESEARCH REVIEWS

Comparative biology of mammalian telomeres: hypotheses on ancestral states and the roles of telomeres in longevity determination

(2011) Nuno M. V. Gomes et al.   AGING CELL

An Improved Likelihood Ratio Test for Detecting Site-Specific Functional Divergence among Clades of Protein-Coding Genes

(2011) Cameron J. Weadick et al.   MOLECULAR BIOLOGY AND EVOLUTION

Genome sequencing reveals insights into physiology and longevity of the naked mole rat

(2011) Eun Bae Kim et al.   NATURE

Impartial comparative analysis of measurement of leukocyte telomere length/DNA content by Southern blots and qPCR

(2011) A. Aviv et al.   NUCLEIC ACIDS RESEARCH

Meraculous: De Novo Genome Assembly with Short Paired-End Reads

(2011) Jarrod A. Chapman et al.   PLoS One

Impacts of the Cretaceous Terrestrial Revolution and KPg Extinction on Mammal Diversification

(2011) R. W. Meredith et al.   SCIENCE

The evolution of sensory divergence in the context of limited gene flow in the bumblebee bat

(2011) Sébastien J. Puechmaille et al.   Nature Communications

Mass extinctions, biodiversity and mitochondrial function: are bats ‘special’ as reservoirs for emerging viruses?

(2011) Lin-Fa Wang et al.   Current Opinion in Virology

ATM-Dependent Chromatin Changes Silence Transcription In cis to DNA Double-Strand Breaks

(2010) Niraj M. Shanbhag et al.   CELL

Role of senataxin in DNA damage and telomeric stability

(2010) Andrea De Amicis et al.   DNA REPAIR

ATR and ATM differently regulate WRN to prevent DSBs at stalled replication forks and promote replication fork recovery

(2010) Francesca Ammazzalorso et al.   EMBO JOURNAL

The Yin and Yang functions of the Myc oncoprotein in cancer development and as targets for therapy

(2010) Lars-Gunnar Larsson et al.   EXPERIMENTAL CELL RESEARCH

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

(2010) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Alternative lengthening of telomeres: models, mechanisms and implications

(2010) Anthony J. Cesare et al.   NATURE REVIEWS GENETICS

Life-history connections to rates of aging in terrestrial vertebrates

(2010) R. E. Ricklefs   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bats and birds: Exceptional longevity despite high metabolic rates

(2009) Jason Munshi-South et al.   AGEING RESEARCH REVIEWS

AQUA: automated quality improvement for multiple sequence alignments

(2009) J. Muller et al.   BIOINFORMATICS

TopHat: discovering splice junctions with RNA-Seq

(2009) Cole Trapnell et al.   BIOINFORMATICS

BLAST+: architecture and applications

(2009) Christiam Camacho et al.   BMC BIOINFORMATICS

Methusaleh's Zoo: How Nature provides us with Clues for Extending Human Health Span

(2009) S.N. Austad   JOURNAL OF COMPARATIVE PATHOLOGY

Amplification efficiency: linking baseline and bias in the analysis of quantitative PCR data

(2009) J. M. Ruijter et al.   NUCLEIC ACIDS RESEARCH

Using native and syntenically mapped cDNA alignments to improve de novo gene finding

(2008) Mario Stanke et al.   BIOINFORMATICS

Phylogeny-Aware Gap Placement Prevents Errors in Sequence Alignment and Evolutionary Analysis

(2008) A. Loytynoja et al.   SCIENCE