Mechanistic Insights Into the Interaction Between Transcription Factors and Epigenetic Modifications and the Contribution to the Development of Obesity

GH prevents adipogenic differentiation of mesenchymal stromal stem cells derived from human trabecular bone via canonical Wnt signaling

(2018) Simona Bolamperti et al.   BONE

miR-205-5p negatively regulates hepatic acetyl-CoA carboxylase β mRNA in lipid metabolism of Oreochromis niloticus

(2018) Yi-Fan Tao et al.   GENE

MicroRNA-200a regulates adipocyte differentiation in the domestic yak Bos grunniens

(2018) Yongfeng Zhang et al.   GENE

CRISPR/Cas-based screening of long non-coding RNAs (lncRNAs) in macrophages with an NF-κB reporter

(2017) Sergio Covarrubias et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Energy stress-induced lncRNA FILNC1 represses c-Myc-mediated energy metabolism and inhibits renal tumor development

(2017) Zhen-Dong Xiao et al.   Nature Communications

Integrated analysis of dosage effect lncRNAs in lung adenocarcinoma based on comprehensive network

(2017) Yunzhen Wei et al.   Oncotarget

Genome-wide analyses of long noncoding RNA expression profiles in lung adenocarcinoma

(2017) Zhenzi Peng et al.   Scientific Reports

Epigenetic Mechanisms of Longevity and Aging

(2016) Payel Sen et al.   CELL

Emerging role of long noncoding RNAs as regulators of innate immune cell development and inflammatory gene expression

(2016) Roland Elling et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Role of TET enzymes in DNA methylation, development, and cancer

(2016) Kasper Dindler Rasmussen et al.   GENES & DEVELOPMENT

The role and possible mechanism of lncRNA U90926 in modulating 3T3-L1 preadipocyte differentiation

(2016) J Chen et al.   INTERNATIONAL JOURNAL OF OBESITY

Identification of key genes induced by platelet-rich plasma in human dermal papilla cells using bioinformatics methods

(2016) Haiyan Shen et al.   Molecular Medicine Reports

Transcription factors as readers and effectors of DNA methylation

(2016) Heng Zhu et al.   NATURE REVIEWS GENETICS

ASBEL–TCF3 complex is required for the tumorigenicity of colorectal cancer cells

(2016) Kenzui Taniue et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Modeling of GR Interactions with the SWI/SNF Chromatin Remodeling Complex and C/EBP

(2015) Serena Muratcioglu et al.   BIOPHYSICAL JOURNAL

A LncRNA-MAF:MAFB Transcription Factor Network Regulates Epidermal Differentiation

(2015) Vanessa Lopez-Pajares et al.   DEVELOPMENTAL CELL

Histone deacetylases: structural determinants of inhibitor selectivity

(2015) Carmina Micelli et al.   DRUG DISCOVERY TODAY

Long Non-Coding RNA Central of Glucose Homeostasis

(2015) Xiangbo Ruan   JOURNAL OF CELLULAR BIOCHEMISTRY

Relationship between expression and methylation of obesity-related genes in children

(2015) Veronica Davé et al.   MUTAGENESIS

Epigenetic silencing of TH1-type chemokines shapes tumour immunity and immunotherapy

(2015) Dongjun Peng et al.   NATURE

Gene expression profiling in myelodysplastic syndrome after SPARC overexpression associated with Ara-C

(2015) QING NIAN et al.   ONCOLOGY REPORTS

Methyl-CpG-binding domain proteins: readers of the epigenome

(2015) Qian Du et al.   Epigenomics

TonEBP suppresses adipogenesis and insulin sensitivity by blocking epigenetic transition of PPARγ2

(2015) Jun Ho Lee et al.   Scientific Reports

Histone Chaperones: Assisting Histone Traffic and Nucleosome Dynamics

(2014) Zachary A. Gurard-Levin et al.   Annual Review of Biochemistry

DNMT3L interacts with transcription factors to target DNMT3L/DNMT3B to specific DNA sequences: Role of the DNMT3L/DNMT3B/p65-NFκB complex in the (de-)methylation of TRAF1

(2014) Romain Pacaud et al.   BIOCHIMIE

Effects of cytosine methylation on transcription factor binding sites

(2014) Yulia A Medvedeva et al.   BMC GENOMICS

RNA regulatory networks in animals and plants: a long noncoding RNA perspective

(2014) Y. Bai et al.   Briefings in Functional Genomics

Nucleosome Structure and Function

(2014) Robert K. McGinty et al.   CHEMICAL REVIEWS

Chromatin remodeling mediated by the FOXA1/A2 transcription factors activatesCFTRexpression in intestinal epithelial cells

(2014) Jenny L Kerschner et al.   Epigenetics

MicroRNA-302a inhibits adipogenesis by suppressing peroxisome proliferator-activated receptor γ expression

(2014) Byung-Chul Jeong et al.   FEBS LETTERS

Downregulation of PPARγ by miR-548d-5p suppresses the adipogenic differentiation of human bone marrow mesenchymal stem cells and enhances their osteogenic potential

(2014) Junkui Sun et al.   Journal of Translational Medicine

ZMYND11 links histone H3.3K36me3 to transcription elongation and tumour suppression

(2014) Hong Wen et al.   NATURE

Discovery of directional and nondirectional pioneer transcription factors by modeling DNase profile magnitude and shape

(2014) Richard I Sherwood et al.   NATURE BIOTECHNOLOGY

Identification of a novel lncRNA in gluteal adipose tissue and evidence for its positive effect on preadipocyte differentiation

(2014) Adeline Divoux et al.   Obesity

Analysis of Transcription Factor Network Underlying 3T3-L1 Adipocyte Differentiation

(2014) KyungOh Choi et al.   PLoS One

Transcriptional and epigenetic regulation of PPARγ expression during adipogenesis

(2014) Ji-Eun Lee et al.   Cell and Bioscience

GPS2/KDM4A Pioneering Activity Regulates Promoter-Specific Recruitment of PPARγ

(2014) M. Dafne Cardamone et al.   Cell Reports

Long Non-Coding RNA NEAT1 Associates with SRp40 to Temporally Regulate PPARγ2 Splicing during Adipogenesis in 3T3-L1 Cells

(2014) Denise Cooper et al.   Genes

Adipocyte and adipogenesis

(2013) Aus Tariq Ali et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Betaine supplement alleviates hepatic triglyceride accumulation of apolipoprotein E deficient mice via reducing methylation of peroxisomal proliferator-activated receptor alpha promoter

(2013) Lijun Wang et al.   Lipids in Health and Disease

Reciprocal Regulation of HIF-1α and LincRNA-p21 Modulates the Warburg Effect

(2013) Fan Yang et al.   MOLECULAR CELL

A pseudogene long-noncoding-RNA network regulates PTEN transcription and translation in human cells

(2013) Per Johnsson et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Transcription factor NFκB regulates the expression of the histone deacetylase SIRT1

(2013) Judith Katto et al.   Clinical Epigenetics

H3K4 mono- and di-methyltransferase MLL4 is required for enhancer activation during cell differentiation

(2013) Ji-Eun Lee et al.   eLife

A mammalian pseudogene lncRNA at the interface of inflammation and anti-inflammatory therapeutics

(2013) Nicole A Rapicavoli et al.   eLife

Protocol for effective differentiation of 3T3-L1 cells to adipocytes

(2012) Katja Zebisch et al.   ANALYTICAL BIOCHEMISTRY

CpG methylation recruits sequence specific transcription factors essential for tissue specific gene expression

(2012) Raghunath Chatterjee et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Brown Remodeling of White Adipose Tissue by SirT1-Dependent Deacetylation of Pparγ

(2012) Li Qiang et al.   CELL

The p400/Brd8 Chromatin Remodeling Complex Promotes Adipogenesis by Incorporating Histone Variant H2A.Z at PPARγ Target Genes

(2012) Jean-Philippe Couture et al.   ENDOCRINOLOGY

MicroRNAs in adipose tissue: their role in adipogenesis and obesity

(2012) C Hilton et al.   INTERNATIONAL JOURNAL OF OBESITY

Epigenetics: The link between nature and nurture

(2012) Stephanie A. Tammen et al.   MOLECULAR ASPECTS OF MEDICINE

Modular regulatory principles of large non-coding RNAs

(2012) Mitchell Guttman et al.   NATURE

LncRNADisease: a database for long-non-coding RNA-associated diseases

(2012) Geng Chen et al.   NUCLEIC ACIDS RESEARCH

Alteration of gene expression in mammary gland tissue of dairy cows in response to dietary unsaturated fatty acids

(2011) N. Mach et al.   Animal

Transcription Factor Loading: Please Take My Place!

(2011) Markus Stratmann et al.   CELL

Dynamic Exchange at Regulatory Elements during Chromatin Remodeling Underlies Assisted Loading Mechanism

(2011) Ty C. Voss et al.   CELL

How epigenetics can explain human metastasis: A new role for microRNAs

(2011) Amaia Lujambio et al.   CELL CYCLE

MicroRNA-375 promotes 3T3-L1 adipocyte differentiation through modulation of extracellular signal-regulated kinase signalling

(2011) Hong-Yan Ling et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

microRNAs in the Regulation of Adipogenesis and Obesity

(2011) R. A. McGregor et al.   CURRENT MOLECULAR MEDICINE

Extensive chromatin remodelling and establishment of transcription factor ‘hotspots’ during early adipogenesis

(2011) Rasmus Siersbaek et al.   EMBO JOURNAL

Pioneer transcription factors: establishing competence for gene expression

(2011) K. S. Zaret et al.   GENES & DEVELOPMENT

CpG islands and the regulation of transcription

(2011) A. M. Deaton et al.   GENES & DEVELOPMENT

Transcription Factor–Dependent Chromatin Remodeling at Heat Shock and Copper-Responsive Promoters inChlamydomonas reinhardtii

(2011) Daniela Strenkert et al.   PLANT CELL

A chromatin perspective of adipogenesis

(2011) Melina M. Musri et al.   Organogenesis

Developmental Origins of Health and Disease: New Insights

(2010) Mark A. Hanson et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

miR-27a is a negative regulator of adipocyte differentiation via suppressing PPARγ expression

(2010) Sang Yun Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Genome-wide conserved consensus transcription factor binding motifs are hyper-methylated

(2010) Mun-Kit Choy et al.   BMC GENOMICS

Combinatorial regulation of transcription factors and microRNAs

(2010) Naifang Su et al.   BMC Systems Biology

Posttranslational modifications of NF-κB: Another layer of regulation for NF-κB signaling pathway

(2010) Bo Huang et al.   CELLULAR SIGNALLING

Decoding the function of nuclear long non-coding RNAs

(2010) Ling-Ling Chen et al.   CURRENT OPINION IN CELL BIOLOGY

PPARγ in adipocyte differentiation and metabolism - Novel insights from genome-wide studies

(2010) Rasmus Siersbaek et al.   FEBS LETTERS

Propagation of adipogenic signals through an epigenomic transition state

(2010) D. J. Steger et al.   GENES & DEVELOPMENT

SIRT1 Deacetylates and Inhibits SREBP-1C Activity in Regulation of Hepatic Lipid Metabolism

(2010) Bhaskar Ponugoti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chromatin accessibility and transcription factor binding at the PPARγ2 promoter during adipogenesis is protein kinase A-dependent

(2010) Hengyi Xiao et al.   JOURNAL OF CELLULAR PHYSIOLOGY

miR-130 Suppresses Adipogenesis by Inhibiting Peroxisome Proliferator-Activated Receptor   Expression

(2010) E. K. Lee et al.   MOLECULAR AND CELLULAR BIOLOGY

Chromatin structure and the inheritance of epigenetic information

(2010) Raphaël Margueron et al.   NATURE REVIEWS GENETICS

A Genetic Mutation in PPARγ Is Associated with Enhanced Fat Cell Differentiation: Implications for Human Obesity

(2010) Hedley C. Freake   NUTRITION REVIEWS

CpG methylation of half-CRE sequences creates C/EBP  binding sites that activate some tissue-specific genes

(2010) V. Rishi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular Signals of Epigenetic States

(2010) Roberto Bonasio et al.   SCIENCE

Chromatin Landscape Dictates HSF Binding to Target DNA Elements

(2010) Michael J. Guertin et al.   PLoS Genetics

Differential epigenomic and transcriptomic responses in subcutaneous adipose tissue between low and high responders to caloric restriction

(2009) Luigi Bouchard et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

The up-regulation of microRNA-335 is associated with lipid metabolism in liver and white adipose tissue of genetically obese mice

(2009) Noriko Nakanishi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

microRNA miR-27b impairs human adipocyte differentiation and targets PPARγ

(2009) Michael Karbiener et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Expression of the peroxisome proliferator activated receptor gamma gene is repressed by DNA methylation in visceral adipose tissue of mouse models of diabetes

(2009) Katsunori Fujiki et al.   BMC BIOLOGY

MicroRNAs Induced During Adipogenesis that Accelerate Fat Cell Development Are Downregulated in Obesity

(2009) H. Xie et al.   DIABETES

Negative regulation of NF-κB action by Set9-mediated lysine methylation of the RelA subunit

(2009) Xiao-Dong Yang et al.   EMBO JOURNAL

Adipose Tissue Dysfunction in Obesity

(2009) M. Blüher   EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES

A role ofmiR-27in the regulation of adipogenesis

(2009) Qun Lin et al.   FEBS Journal

GCN5 is a required cofactor for a ubiquitin ligase that targets NF- B/RelA

(2009) X. Mao et al.   GENES & DEVELOPMENT

The Peroxisome Proliferator-Activated Receptor  /Retinoid X Receptor   Heterodimer Targets the Histone Modification Enzyme PR-Set7/Setd8 Gene and Regulates Adipogenesis through a Positive Feedback Loop

(2009) K.-i. Wakabayashi et al.   MOLECULAR AND CELLULAR BIOLOGY

PPARs and adipocyte function

(2009) Constantinos Christodoulides et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Histone H3 Lysine 56 Acetylation Is Linked to the Core Transcriptional Network in Human Embryonic Stem Cells

(2009) Wei Xie et al.   MOLECULAR CELL

Wnt and PPARγ signaling in osteoblastogenesis and adipogenesis

(2009) Ichiro Takada et al.   Nature Reviews Rheumatology

Combinatorial network of primary and secondary microRNA-driven regulatory mechanisms

(2009) Kang Tu et al.   NUCLEIC ACIDS RESEARCH

The role of PPARα in lipid metabolism and obesity: Focusing on the effects of estrogen on PPARα actions

(2009) Michung Yoon   PHARMACOLOGICAL RESEARCH

Regulation of NF- B by NSD1/FBXL11-dependent reversible lysine methylation of p65

(2009) T. Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fat and Beyond: The Diverse Biology of PPARγ

(2008) Peter Tontonoz et al.   Annual Review of Biochemistry

Adipogenesis licensing and execution are disparately linked to cell proliferation

(2008) Wei Guo et al.   CELL RESEARCH

PPAR  and C/EBP factors orchestrate adipocyte biology via adjacent binding on a genome-wide scale

(2008) M. I. Lefterova et al.   GENES & DEVELOPMENT

p53-repressed miRNAs are involved with E2F in a feed-forward loop promoting proliferation

(2008) Ran Brosh et al.   Molecular Systems Biology

Analysis of regulatory network topology reveals functionally distinct classes of microRNAs

(2008) Xueping Yu et al.   NUCLEIC ACIDS RESEARCH

Functional relevance of novel p300-mediated lysine 314 and 315 acetylation of RelA/p65

(2008) Christine Buerki et al.   NUCLEIC ACIDS RESEARCH