Homeobox a5 Promotes White Adipose Tissue Browning Through Inhibition of the Tenascin C/Toll-Like Receptor 4/Nuclear Factor Kappa B Inflammatory Signaling in Mice

Foxc2 coordinates inflammation and browning of white adipose by leptin-STAT3-PRDM16 signal in mice

(2017) L Gan et al.   INTERNATIONAL JOURNAL OF OBESITY

Hox5Paralogous Genes Modulate Th2 Cell Function during Chronic Allergic Inflammation via Regulation ofGata3

(2017) Catherine Ptaschinski et al.   JOURNAL OF IMMUNOLOGY

Melatonin promotes circadian rhythm-induced proliferation through Clock/histone deacetylase 3/c-Myc interaction in mouse adipose tissue

(2017) Zhenjiang Liu et al.   JOURNAL OF PINEAL RESEARCH

Melatonin alleviates inflammasome-induced pyroptosis through inhibiting NF-κB/GSDMD signal in mice adipose tissue

(2017) Zhenjiang Liu et al.   JOURNAL OF PINEAL RESEARCH

ColXV promotes adipocyte differentiation via inhibiting DNA methylation and cAMP/PKA pathway in mice

(2017) Guannv Liu et al.   Oncotarget

αMSH prevents ROS-induced apoptosis by inhibiting Foxo1/mTORC2 in mice adipose tissue

(2017) Weina Cao et al.   Oncotarget

αMSH inhibits adipose inflammation via reducing FoxOs transcription and blocking Akt/JNK pathway in mice

(2017) Guannv Liu et al.   Oncotarget

BMP4 Gene Therapy in Mature Mice Reduces BAT Activation but Protects from Obesity by Browning Subcutaneous Adipose Tissue

(2017) Jenny M. Hoffmann et al.   Cell Reports

Reduced Endoplasmic Reticulum Stress-Mediated Autophagy Is Required for Leptin Alleviating Inflammation in Adipose Tissue

(2017) Lu Gan et al.   Frontiers in Immunology

Effects of Moderate and Subsequent Progressive Weight Loss on Metabolic Function and Adipose Tissue Biology in Humans with Obesity

(2016) Faidon Magkos et al.   Cell Metabolism

IL-18 Production from the NLRP1 Inflammasome Prevents Obesity and Metabolic Syndrome

(2016) Andrew J. Murphy et al.   Cell Metabolism

Caloric Restriction Leads to Browning of White Adipose Tissue through Type 2 Immune Signaling

(2016) Salvatore Fabbiano et al.   Cell Metabolism

Proinflammatory cytokine interleukin-1β suppresses cold-induced thermogenesis in adipocytes

(2016) Tsuyoshi Goto et al.   CYTOKINE

PPARγ Antagonist Gleevec Improves Insulin Sensitivity and Promotes the Browning of White Adipose Tissue

(2016) Sun-Sil Choi et al.   DIABETES

Hoxa5 undergoes dynamic DNA methylation and transcriptional repression in the adipose tissue of mice exposed to high-fat diet

(2016) L Parrillo et al.   INTERNATIONAL JOURNAL OF OBESITY

Targeting adipose tissue in the treatment of obesity-associated diabetes

(2016) Christine M. Kusminski et al.   NATURE REVIEWS DRUG DISCOVERY

Reducing Smad3/ATF4 was essential for Sirt1 inhibiting ER stress-induced apoptosis in mice brown adipose tissue

(2016) Zhenjiang Liu et al.   Oncotarget

α-MSH and Foxc2 promote fatty acid oxidation through C/EBPβ negative transcription in mice adipose tissue

(2016) Lu Gan et al.   Scientific Reports

Adipose Tissue Remodeling: Its Role in Energy Metabolism and Metabolic Disorders

(2016) Sung Sik Choe et al.   Frontiers in Endocrinology

Mark4 promotes oxidative stress and inflammation via binding to PPARγ and activating NF-κB pathway in mice adipocytes

(2016) Zhenjiang Liu et al.   Scientific Reports

High-fat diet induced obesity primes inflammation in adipose tissue prior to liver in C57BL/6j mice

(2015) Roel A van der Heijden et al.   Aging-US

Activation of Toll-like Receptor 4 (TLR4) Attenuates Adaptive Thermogenesis via Endoplasmic Reticulum Stress

(2015) Meshail Okla et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Distinct Developmental Profile of Lower-Body Adipose Tissue Defines Resistance Against Obesity-Associated Metabolic Complications

(2014) Katherine E. Pinnick et al.   DIABETES

Inhibiting DNA Methylation by 5-Aza-2′-deoxycytidine Ameliorates Atherosclerosis Through Suppressing Macrophage Inflammation

(2014) Qiang Cao et al.   ENDOCRINOLOGY

The different shades of fat

(2014) Vivian Peirce et al.   NATURE

Visceral and subcutaneous fat have different origins and evidence supports a mesothelial source

(2014) You-Ying Chau et al.   NATURE CELL BIOLOGY

Inflammasomes and Metabolic Disease

(2013) Jorge Henao-Mejia et al.   Annual Review of Physiology

Lipopolysaccharide-induced inhibition of transcription of tlr4 in vitro is reversed by dexamethasone and correlates with presence of conserved NFκB binding sites

(2013) Camila P. Bonin et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

BMP4-mediated brown fat-like changes in white adipose tissue alter glucose and energy homeostasis

(2013) Shu-Wen Qian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PPARγ agonists Induce a White-to-Brown Fat Conversion through Stabilization of PRDM16 Protein

(2012) Haruya Ohno et al.   Cell Metabolism

TLR-induced NF-κB activation regulates NLRP3 expression in murine macrophages

(2012) Yu Qiao et al.   FEBS LETTERS

A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis

(2012) Pontus Boström et al.   NATURE

Human HOXA5 homeodomain enhances protein transduction and its application to vascular inflammation

(2011) Ji Young Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Advances in tenascin-C biology

(2011) Kim S. Midwood et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Developmental Origins of the Adipocyte Lineage: New Insights from Genetics and Genomics Studies

(2011) Nathalie Billon et al.   Stem Cell Reviews and Reports

Inflammatory Role of Toll-Like Receptors in Human and Murine Adipose Tissue

(2010) Odile Poulain-Godefroy et al.   MEDIATORS OF INFLAMMATION

Adipose Depots Possess Unique Developmental Gene Signatures

(2010) Yuji Yamamoto et al.   Obesity

Switch from Stress Response to Homeobox Transcription Factors in Adipose Tissue After Profound Fat Loss

(2010) Simon N. Dankel et al.   PLoS One

High Incidence of Metabolically Active Brown Adipose Tissue in Healthy Adult Humans: Effects of Cold Exposure and Adiposity

(2009) M. Saito et al.   DIABETES

Tenascin-C is an endogenous activator of Toll-like receptor 4 that is essential for maintaining inflammation in arthritic joint disease

(2009) Kim Midwood et al.   NATURE MEDICINE