Transcription Factor Retinoid-Related Orphan Receptor γt: A Promising Target for the Treatment of Psoriasis
出版年份 2018 全文链接
标题
Transcription Factor Retinoid-Related Orphan Receptor γt: A Promising Target for the Treatment of Psoriasis
作者
关键词
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出版物
Frontiers in Immunology
Volume 9, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2018-05-30
DOI
10.3389/fimmu.2018.01210
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Pharmacological inhibitory profile of TAK-828F, a potent and selective orally available RORγt inverse agonist
- (2018) Akira Shibata et al. BIOCHEMICAL PHARMACOLOGY
- Targeting RORs nuclear receptors by novel synthetic steroidal inverse agonists for autoimmune disorders
- (2018) Matteo Dal Prà et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Discovery of carbazole carboxamides as novel RORγt inverse agonists
- (2018) Yafei Huang et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Role of the IL-23/IL-17 Axis in Psoriasis and Psoriatic Arthritis: The Clinical Importance of Its Divergence in Skin and Joints
- (2018) Marie-Astrid Boutet et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Psoriasis: A STAT3-Centric View
- (2018) et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Rates of latent tuberculosis infection in patients treated with TNF inhibitors for psoriasis: a retrospective chart review
- (2018) Erica B. Lee et al. JOURNAL OF DERMATOLOGICAL TREATMENT
- Change over time in the rates of adverse events in patients receiving systemic therapy for psoriasis: A cohort study
- (2018) Miguel Angel Descalzo et al. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
- Cardiometabolic Comorbidities in Psoriasis and Psoriatic Arthritis
- (2017) Lluís Puig INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Oral administration of a novel RORγt antagonist attenuates psoriasis-like skin lesion of two independent mouse models through neutralization of IL-17
- (2017) Mikiro Takaishi et al. JOURNAL OF DERMATOLOGICAL SCIENCE
- Pathogenesis of psoriasis and development of treatment
- (2017) Eisaku Ogawa et al. JOURNAL OF DERMATOLOGY
- Adverse events associated with discontinuation of the biologics/classic systemic treatments for moderate-to-severe plaque psoriasis: data from the Spanish Biologics Registry, Biobadaderm
- (2017) I. Belinchón et al. JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
- Contribution of In Vivo and Organotypic 3D Models to Understanding the Role of Macrophages and Neutrophils in the Pathogenesis of Psoriasis
- (2017) Isabelle Lorthois et al. MEDIATORS OF INFLAMMATION
- Healthcare costs in psoriasis and psoriasis sub-groups over time following psoriasis diagnosis
- (2017) Sarah Al Sawah et al. JOURNAL OF MEDICAL ECONOMICS
- Interleukin-17A-induced production of acute serum amyloid A by keratinocytes contributes to psoriasis pathogenesis
- (2017) Elodie Couderc et al. PLoS One
- The psoriasis-associated IL-17A induces and cooperates with IL-36 cytokines to control keratinocyte differentiation and function
- (2017) Carolina M. Pfaff et al. Scientific Reports
- Pathogenese der Psoriasis vulgaris
- (2016) K. Schäkel et al. HAUTARZT
- Interleukin-23-Induced Transcription Factor Blimp-1 Promotes Pathogenicity of T Helper 17 Cells
- (2016) Renu Jain et al. IMMUNITY
- IL-35 Decelerates the Inflammatory Process by Regulating Inflammatory Cytokine Secretion and M1/M2 Macrophage Ratio in Psoriasis
- (2016) Junfeng Zhang et al. JOURNAL OF IMMUNOLOGY
- Keratinocyte-Derived IL-17E Contributes to Inflammation in Psoriasis
- (2016) Luisa Senra et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- T cell–intrinsic ASC critically promotes TH17-mediated experimental autoimmune encephalomyelitis
- (2016) Bradley N Martin et al. NATURE IMMUNOLOGY
- Erratum: Corrigendum: ROR-γ drives androgen receptor expression and represents a therapeutic target in castration-resistant prostate cancer
- (2016) Junjian Wang et al. NATURE MEDICINE
- Psoriasis
- (2016) Jacqueline E. Greb et al. Nature Reviews Disease Primers
- Psoriasis: classical and emerging comorbidities
- (2015) Maria de Fátima Santos Paim de Oliveira et al. ANAIS BRASILEIROS DE DERMATOLOGIA
- T cell responses in psoriasis and psoriatic arthritis
- (2015) Marco Diani et al. AUTOIMMUNITY REVIEWS
- The global burden of psoriatic skin disease
- (2015) K.L. Goff et al. BRITISH JOURNAL OF DERMATOLOGY
- ROR Inverse Agonist Suppresses Insulitis and Prevents Hyperglycemia in a Mouse Model of Type 1 Diabetes
- (2015) Laura A. Solt et al. ENDOCRINOLOGY
- Evidence that a neutrophil-keratinocyte crosstalk is an early target of IL-17A inhibition in psoriasis
- (2015) Kristian Reich et al. EXPERIMENTAL DERMATOLOGY
- Secukinumab for treating plaque psoriasis
- (2015) Brooke Rothstein et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- Digoxin ameliorates autoimmune arthritis via suppression of Th17 differentiation
- (2015) Jennifer Lee et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- The immunogenetics of Psoriasis: A comprehensive review
- (2015) Jamie L. Harden et al. JOURNAL OF AUTOIMMUNITY
- Psoriasis
- (2015) Wolf-Henning Boehncke et al. LANCET
- Targeting Th17 Cells with Small Molecules and Small Interference RNA
- (2015) Hui Lin et al. MEDIATORS OF INFLAMMATION
- Economic Burden of Psoriasis in the United States
- (2015) Elizabeth A. Brezinski et al. JAMA Dermatology
- Ursolic acid ameliorates autoimmune arthritis via suppression of Th17 and B cell differentiation
- (2014) Seung-ye Baek et al. ACTA PHARMACOLOGICA SINICA
- The pathophysiological role of dendritic cell subsets in psoriasis
- (2014) Tae-Gyun Kim et al. BMB Reports
- Small-Molecule RORγt Antagonists Inhibit T Helper 17 Cell Transcriptional Network by Divergent Mechanisms
- (2014) Sheng Xiao et al. IMMUNITY
- Pharmacologic Inhibition of ROR t Regulates Th17 Signature Gene Expression and Suppresses Cutaneous Inflammation In Vivo
- (2014) J. Skepner et al. JOURNAL OF IMMUNOLOGY
- Impact of psoriasis severity on family income and quality of life
- (2014) T. Hawro et al. JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
- The antimicrobial peptide LL37 is a T-cell autoantigen in psoriasis
- (2014) Roberto Lande et al. Nature Communications
- Ursolic acid promotes colorectal cancer cell apoptosis and inhibits cell proliferation via modulation of multiple signaling pathways
- (2013) JIUMAO LIN et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- In Vivo Induction of Cutaneous Inflammation Results in the Accumulation of Extracellular Trap-Forming Neutrophils Expressing RORγt and IL-17
- (2013) Romy R.M.C Keijsers et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- The Global Burden of Skin Disease in 2010: An Analysis of the Prevalence and Impact of Skin Conditions
- (2013) Roderick J. Hay et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Induction of pathogenic TH17 cells by inducible salt-sensing kinase SGK1
- (2013) Chuan Wu et al. NATURE
- Ursolic Acid Inhibits Adipogenesis in 3T3-L1 Adipocytes through LKB1/AMPK Pathway
- (2013) Yonghan He et al. PLoS One
- Pharmacologic Repression of Retinoic Acid Receptor-Related Orphan Nuclear Receptor γ Is Therapeutic in the Collagen-Induced Arthritis Experimental Model
- (2013) Mi Ra Chang et al. Arthritis & Rheumatology
- Identification of SR2211: A Potent Synthetic RORγ-Selective Modulator
- (2012) Naresh Kumar et al. ACS Chemical Biology
- Inflammatory T Helper 17 Cells Promote Depression-like Behavior in Mice
- (2012) Eléonore Beurel et al. BIOLOGICAL PSYCHIATRY
- Ursolic acid promotes the neuroprotection by activating Nrf2 pathway after cerebral ischemia in mice
- (2012) Litao Li et al. BRAIN RESEARCH
- Depression and the risk of psoriasis in US women
- (2012) P.L. Dominguez et al. JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
- Induction and molecular signature of pathogenic TH17 cells
- (2012) Youjin Lee et al. NATURE IMMUNOLOGY
- Ursolic Acid Suppresses Interleukin-17 (IL-17) Production by Selectively Antagonizing the Function of RORγt Protein
- (2011) Tao Xu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structural Basis of Digoxin That Antagonizes RORγt Receptor Activity and Suppresses Th17 Cell Differentiation and Interleukin (IL)-17 Production
- (2011) Saori Fujita-Sato et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Digoxin and its derivatives suppress TH17 cell differentiation by antagonizing RORγt activity
- (2011) Jun R. Huh et al. NATURE
- Suppression of TH17 differentiation and autoimmunity by a synthetic ROR ligand
- (2011) Laura A. Solt et al. NATURE
- Increased interleukin-23 receptor+ T cells in peripheral blood mononuclear cells of patients with systemic lupus erythematosus
- (2011) Hathaipat Puwipirom et al. ARTHRITIS RESEARCH & THERAPY
- A second class of nuclear receptors for oxysterols: Regulation of RORα and RORγ activity by 24S-hydroxycholesterol (cerebrosterol)
- (2010) Yongjun Wang et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Human fibroblasts support the expansion of IL-17-producing T cells via up-regulation of IL-23 production by dendritic cells
- (2010) C. Schirmer et al. BLOOD
- Generation of pathogenic TH17 cells in the absence of TGF-β signalling
- (2010) Kamran Ghoreschi et al. NATURE
- Modulation of Retinoic Acid Receptor-related Orphan Receptor α and γ Activity by 7-Oxygenated Sterol Ligands
- (2009) Yongjun Wang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Guidelines of care for the management of psoriasis and psoriatic arthritis
- (2009) Alan Menter et al. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
- The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17–producing effector T helper cells in vivo
- (2009) Mandy J McGeachy et al. NATURE IMMUNOLOGY
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