CD19+CD24hiCD38hi B Cells Are Expanded in Juvenile Dermatomyositis and Exhibit a Pro-Inflammatory Phenotype After Activation Through Toll-Like Receptor 7 and Interferon-α

Sifalimumab, an anti-interferon-α monoclonal antibody, in moderate to severe systemic lupus erythematosus: a randomised, double-blind, placebo-controlled study

(2016) Munther Khamashta et al.   ANNALS OF THE RHEUMATIC DISEASES

Alpha and Beta Type 1 Interferon Signaling: Passage for Diverse Biologic Outcomes

(2016) Cherie T. Ng et al.   CELL

A Regulatory Feedback between Plasmacytoid Dendritic Cells and Regulatory B Cells Is Aberrant in Systemic Lupus Erythematosus

(2016) Madhvi Menon et al.   IMMUNITY

Role of regulatory B cells in immune tolerance to allergens and beyond

(2016) Willem van de Veen et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Breg Cells Are Numerically Decreased and Functionally Impaired in Patients With Systemic Sclerosis

(2016) Athanasios Mavropoulos et al.   Arthritis & Rheumatology

The Regulatory B Cell Compartment Expands Transiently During Childhood and Is Contracted in Children With Autoimmunity

(2016) Ioannis Kalampokis et al.   Arthritis & Rheumatology

Muscle Biopsy Findings in Combination With Myositis-Specific Autoantibodies Aid Prediction of Outcomes in Juvenile Dermatomyositis

(2016) Claire T. Deakin et al.   Arthritis & Rheumatology

Significant decrease in peripheral regulatory B cells is an immunopathogenic feature of dermatomyositis

(2016) Wenli Li et al.   Scientific Reports

A Phase II study of the efficacy and safety of rontalizumab (rhuMAb interferon-α) in patients with systemic lupus erythematosus (ROSE)

(2015) Kenneth C Kalunian et al.   ANNALS OF THE RHEUMATIC DISEASES

The immune balance between memory and regulatory B cells in NMO and the changes of the balance after methylprednisolone or rituximab therapy

(2015) Chao Quan et al.   JOURNAL OF NEUROIMMUNOLOGY

Differential effects of cyclophosphamide and mycophenolate mofetil on cellular and serological parameters in patients with systemic lupus erythematosus

(2015) Till Fassbinder et al.   ARTHRITIS RESEARCH & THERAPY

TLR-mediated STAT3 and ERK activation controls IL-10 secretion by human B cells

(2014) Bi-Sheng Liu et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Interleukin-10-Producing Plasmablasts Exert Regulatory Function in Autoimmune Inflammation

(2014) Masanori Matsumoto et al.   IMMUNITY

Regulatory B cells are numerically but not functionally deficient in anti-neutrophil cytoplasm antibody-associated vasculitis

(2014) S. K. Todd et al.   RHEUMATOLOGY

Calcinosis in juvenile dermatomyositis is influenced by both anti-NXP2 autoantibody status and age at disease onset

(2014) Sarah L. Tansley et al.   RHEUMATOLOGY

Myositis Specific and Associated Autoantibodies in the Diagnosis and Management of Juvenile and Adult Idiopathic Inflammatory Myopathies

(2014) Sarah L. Tansley et al.   Current Rheumatology Reports

Correlation of CXCL10, Tumor Necrosis Factor Receptor Type II, and Galectin 9 With Disease Activity in Juvenile Dermatomyositis

(2014) F. Bellutti Enders et al.   Arthritis & Rheumatology

Distinct Effects of Methotrexate and Etanercept on the B Cell Compartment in Patients With Juvenile Idiopathic Arthritis

(2014) Stephanie Glaesener et al.   Arthritis & Rheumatology

Validation of a score tool for measurement of histological severity in juvenile dermatomyositis and association with clinical severity of disease

(2013) Hemlata Varsani et al.   ANNALS OF THE RHEUMATIC DISEASES

A phase 1b clinical trial evaluating sifalimumab, an anti-IFN-α monoclonal antibody, shows target neutralisation of a type I IFN signature in blood of dermatomyositis and polymyositis patients

(2013) Brandon W Higgs et al.   ANNALS OF THE RHEUMATIC DISEASES

Serum Interleukin-6 Expression Level and Its Clinical Significance in Patients with Dermatomyositis

(2013) Min Yang et al.   Clinical & Developmental Immunology

Update in juvenile myositis

(2013) Kiran Nistala et al.   CURRENT OPINION IN RHEUMATOLOGY

IgG4 production is confined to human IL-10–producing regulatory B cells that suppress antigen-specific immune responses

(2013) Willem van de Veen et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Overexpression of TLR7 promotes cell-intrinsic expansion and autoantibody production by transitional T1 B cells

(2013) Natalia V. Giltiay et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CD19+CD24hiCD38hi B Cells Maintain Regulatory T Cells While Limiting TH1 and TH17 Differentiation

(2013) F. Flores-Borja et al.   Science Translational Medicine

TLR7 and TLR9 in SLE: when sensing self goes wrong

(2012) T. Celhar et al.   IMMUNOLOGIC RESEARCH

Role of type I interferons in the activation of autoreactive B cells

(2012) Kerstin Kiefer et al.   IMMUNOLOGY AND CELL BIOLOGY

B Cell TLR7 Expression Drives Anti-RNA Autoantibody Production and Exacerbates Disease in Systemic Lupus Erythematosus-Prone Mice

(2012) S.-H. Hwang et al.   JOURNAL OF IMMUNOLOGY

Patients with systemic lupus erythematosus, myositis, rheumatoid arthritis and scleroderma share activation of a common type I interferon pathway

(2011) B. W. Higgs et al.   ANNALS OF THE RHEUMATIC DISEASES

IRF7: activation, regulation, modification and function

(2011) S Ning et al.   GENES AND IMMUNITY

Hematopoietic Stem Cell Gene Therapy for Adenosine Deaminase-Deficient Severe Combined Immunodeficiency Leads to Long-Term Immunological Recovery and Metabolic Correction

(2011) H. B. Gaspar et al.   Science Translational Medicine

Type I interferon pathway in adult and juvenile dermatomyositis

(2011) Emily C Baechler et al.   ARTHRITIS RESEARCH & THERAPY

Characterization of a rare IL-10-competent B-cell subset in humans that parallels mouse regulatory B10 cells

(2010) Y. Iwata et al.   BLOOD

Reference values for B cell subpopulations from infancy to adulthood

(2010) H. Morbach et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Simultaneous quantification of recent thymic T-cell and bone marrow B-cell emigrants in patients with primary immunodeficiency undergone to stem cell transplantation

(2010) Alessandra Sottini et al.   CLINICAL IMMUNOLOGY

CD19+CD24hiCD38hi B Cells Exhibit Regulatory Capacity in Healthy Individuals but Are Functionally Impaired in Systemic Lupus Erythematosus Patients

(2010) Paul A. Blair et al.   IMMUNITY

Type I interferon: friend or foe?

(2010) Giorgio Trinchieri   JOURNAL OF EXPERIMENTAL MEDICINE

A national registry for juvenile dermatomyositis and other paediatric idiopathic inflammatory myopathies: 10 years' experience; the Juvenile Dermatomyositis National (UK and Ireland) Cohort Biomarker Study and Repository for Idiopathic Inflammatory Myopathies

(2010) Neil Martin et al.   RHEUMATOLOGY

Validation of manual muscle testing and a subset of eight muscles for adult and juvenile idiopathic inflammatory myopathies

(2010) Lisa G. Rider et al.   ARTHRITIS CARE & RESEARCH

Interleukin-6 and type I interferon-regulated genes and chemokines mark disease activity in dermatomyositis

(2009) Hatice Bilgic et al.   ARTHRITIS AND RHEUMATISM

Extranodal lymphoid microstructures in inflamed muscle and disease severity of new-onset juvenile dermatomyositis

(2009) Consuelo M. López De Padilla et al.   ARTHRITIS AND RHEUMATISM

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Molecular mechanism and function of CD40/CD40L engagement in the immune system

(2009) Raul Elgueta et al.   IMMUNOLOGICAL REVIEWS

Murine B Cell Response to TLR7 Ligands Depends on an IFN-  Feedback Loop

(2009) N. M. Green et al.   JOURNAL OF IMMUNOLOGY

TLR7 and CD40 cooperate in IL-6 productionviaenhanced JNK and AP-1 activation

(2008) Tony J. Vanden Bush et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Plasmacytoid dendritic cells are present in cutaneous dermatomyositis lesions in a pattern distinct from lupus erythematosus

(2007) Jennifer M. McNiff et al.   JOURNAL OF CUTANEOUS PATHOLOGY

Quantification of normal range of inflammatory changes in morphologically normal pediatric muscle

(2007) Hemlata Varsani et al.   MUSCLE & NERVE