Oral Nonviral Gene Delivery for Chronic Protein Replacement Therapy

Ultrasmall Conjugated Polymer Nanoparticles with High Specificity for Targeted Cancer Cell Imaging

(2017) Guangxue Feng et al.   Advanced Science

Rod-Shaped Active Drug Particles Enable Efficient and Safe Gene Delivery

(2017) Xiaofei Xin et al.   Advanced Science

Genome Editing for Cancer Therapy: Delivery of Cas9 Protein/sgRNA Plasmid via a Gold Nanocluster/Lipid Core-Shell Nanocarrier

(2017) Peng Wang et al.   Advanced Science

Synergistic nanomedicine by combined gene and photothermal therapy

(2016) Jinhwan Kim et al.   ADVANCED DRUG DELIVERY REVIEWS

Continuous Production of Discrete Plasmid DNA-Polycation Nanoparticles Using Flash Nanocomplexation

(2016) Jose Luis Santos et al.   Small

Grafting Chitosan with Polyethylenimine in an Ionic Liquid for Efficient Gene Delivery

(2015) Huiying Chen et al.   PLoS One

Chitosan-Graft-Polyethylenimine/DNA Nanoparticles as Novel Non-Viral Gene Delivery Vectors Targeting Osteoarthritis

(2014) Huading Lu et al.   PLoS One

Chitosans for delivery of nucleic acids

(2013) Michael D. Buschmann et al.   ADVANCED DRUG DELIVERY REVIEWS

Combination therapy via oral co-administration of insulin- and exendin-4-loaded nanoparticles to treat type 2 diabetic rats undergoing OGTT

(2013) Er-Yuan Chuang et al.   BIOMATERIALS

Effects of pH on molecular mechanisms of chitosan–integrin interactions and resulting tight-junction disruptions

(2012) Li-Wen Hsu et al.   BIOMATERIALS

Chitosan-Graft-Branched Polyethylenimine Copolymers: Influence of Degree of Grafting on Transfection Behavior

(2012) Daniele Pezzoli et al.   PLoS One

Intestinal delivery of non-viral gene therapeutics: physiological barriers and preclinical models

(2011) Martin J. O’Neill et al.   DRUG DISCOVERY TODAY

Uptake mechanisms of non-viral gene delivery

(2011) Shengnan Xiang et al.   JOURNAL OF CONTROLLED RELEASE

In vivobiodistribution of nanoparticles

(2011) Joao Paulo Mattos Almeida et al.   Nanomedicine

Biodistribution, pharmacodynamics and pharmacokinetics of insulin analogues in a rat model: Oral delivery using pH-Responsive nanoparticles vs. subcutaneous injection

(2010) Kiran Sonaje et al.   BIOMATERIALS

Enteric-coated capsules filled with freeze-dried chitosan/poly(γ-glutamic acid) nanoparticles for oral insulin delivery

(2010) Kiran Sonaje et al.   BIOMATERIALS

Mechanisms of cellular uptake and intracellular trafficking with chitosan/DNA/poly(γ-glutamic acid) complexes as a gene delivery vector

(2010) Shu-Fen Peng et al.   BIOMATERIALS

Emerging links between surface nanotechnology and endocytosis: Impact on nonviral gene delivery

(2010) Andrew F. Adler et al.   Nano Today

Comparative structural and functional studies of nanoparticle formulations for DNA and siRNA delivery

(2010) Albert Kwok et al.   Nanomedicine-Nanotechnology Biology and Medicine

In vivo evaluation of safety and efficacy of self-assembled nanoparticles for oral insulin delivery

(2009) Kiran Sonaje et al.   BIOMATERIALS

Chitosan-graft-polyethylenimine with improved properties as a potential gene vector

(2009) Zong-Tao Li et al.   CARBOHYDRATE POLYMERS

TMC–MCC (N-trimethyl chitosan–mono-N-carboxymethyl chitosan) nanocomplexes for mucosal delivery of vaccines

(2009) Burcu Sayın et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Oral IL-10 gene delivery in a microsphere-based formulation for local transfection and therapeutic efficacy in inflammatory bowel disease

(2008) M D Bhavsar et al.   GENE THERAPY

Gene transfer to hemophilia A mice via oral delivery of FVIII–chitosan nanoparticles

(2008) Katherine Bowman et al.   JOURNAL OF CONTROLLED RELEASE

Gene transfer into guinea pig cochlea using adeno-associated virus vectors

(2008) Masaya Konishi et al.   JOURNAL OF GENE MEDICINE