Integrin α9 Suppresses Hepatocellular Carcinoma Metastasis by Rho GTPase Signaling

SPON2 Promotes M1-like Macrophage Recruitment and Inhibits Hepatocellular Carcinoma Metastasis by Distinct Integrin–Rho GTPase–Hippo Pathways

(2018) Yan-Li Zhang et al.   CANCER RESEARCH

Toxoplasma gondiidisrupts β1 integrin signaling and focal adhesion formation during monocyte hypermotility

(2018) Joshua H. Cook et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Increased Serotonin Signaling Contributes to the Warburg Effect in Pancreatic Tumor Cells Under Metabolic Stress and Promotes Growth of Pancreatic Tumors in Mice

(2017) Shu-Heng Jiang et al.   GASTROENTEROLOGY

Suppression of RAC1-driven malignant melanoma by group A PAK inhibitors

(2017) D Araiza-Olivera et al.   ONCOGENE

Comprehensive analysis of normal adjacent to tumor transcriptomes

(2017) Dvir Aran et al.   Nature Communications

3D Microstructure Inhibits Mesenchymal Stem Cells Homing to the Site of Liver Cancer Cells on a Microchip

(2017) Xingyuan Yang et al.   Genes

17β-estradiol exerts anticancer effects in anoikis-resistant hepatocellular carcinoma cell lines by targeting IL-6/STAT3 signaling

(2016) Seulki Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Hepatic stellate cells induce hepatocellular carcinoma cell resistance to sorafenib through the laminin-332/α3 integrin axis recovery of focal adhesion kinase ubiquitination

(2016) Amalia Azzariti et al.   HEPATOLOGY

Thyroid hormone receptor β1 suppresses proliferation and migration by inhibiting PI3K/Akt signaling in human colorectal cancer cells

(2016) Lei Zhu et al.   ONCOLOGY REPORTS

Integrin α9 gene promoter is hypermethylated and downregulated in nasopharyngeal carcinoma

(2015) Imran Nawaz et al.   Oncotarget

Hepatocellular Carcinoma

(2015) M.-A. Buendia et al.   Cold Spring Harbor Perspectives in Medicine

DNA methylation-mediated silencing of matricellular protein dermatopontin promotes hepatocellular carcinoma metastasis by α3β1 integrin-Rho GTPase signaling

(2015) Ying Fu et al.   Oncotarget

Monoamine oxidase A suppresses hepatocellular carcinoma metastasis by inhibiting the adrenergic system and its transactivation of EGFR signaling

(2014) Jun Li et al.   JOURNAL OF HEPATOLOGY

Strategies To Inhibit Tumor Associated Integrin Receptors: Rationale for Dual and Multi-Antagonists

(2014) Helen M. Sheldrake et al.   JOURNAL OF MEDICINAL CHEMISTRY

Elevated autocrine EDIL3 protects hepatocellular carcinoma from anoikis through RGD-mediated integrin activation

(2014) Ming-Xuan Feng et al.   Molecular Cancer

Recurrent gain-of-function mutations of RHOA in diffuse-type gastric carcinoma

(2014) Miwako Kakiuchi et al.   NATURE GENETICS

Tissue factor pathway inhibitor-2: A novel gene involved in zebrafish central nervous system development

(2013) Yanli Zhang et al.   DEVELOPMENTAL BIOLOGY

Integrin α9β1 promotes malignant tumor growth and metastasis by potentiating epithelial-mesenchymal transition

(2012) S K Gupta et al.   ONCOGENE

Hypoxia-inducible factor 1 alpha-activated angiopoietin-like protein 4 contributes to tumor metastasis via vascular cell adhesion molecule-1/integrin β1 signaling in human hepatocellular carcinoma

(2011) Hong Li et al.   HEPATOLOGY

Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progression

(2011) Mina J Bissell et al.   NATURE MEDICINE

Frequent alterations of the candidate genes hMLH1, ITGA9 and RBSP3 in early dysplastic lesions of head and neck: Clinical and prognostic significance

(2010) Amlan Ghosh et al.   CANCER SCIENCE

Vascular Endothelial Growth Factor A (VEGF-A) Induces Endothelial and Cancer Cell Migration through Direct Binding to Integrin α9β1

(2010) Saji Oommen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Clinical and functional significance of α9β1 integrin expression in breast cancer: a novel cell-surface marker of the basal phenotype that promotes tumour cell invasion

(2010) Michael D Allen et al.   JOURNAL OF PATHOLOGY

Expression of integrin α9 subunit and tenascin in oral leukoplakia, lichen planus, and squamous cell carcinoma

(2010) L Häkkinen et al.   ORAL DISEASES

α9β1 Integrin in melanoma cells can signal different adhesion states for migration and anchorage

(2009) Magnus C. Lydolph et al.   EXPERIMENTAL CELL RESEARCH

Molecular targeted therapies in hepatocellular carcinoma: From pre-clinical models to clinical trials

(2008) Pippa Newell et al.   JOURNAL OF HEPATOLOGY

Downregulation of RBSP3/CTDSPL, NPRL2/G21, RASSF1A, ITGA9, HYAL1, and HYAL2 in non-small cell lung cancer

(2008) E. A. Anedchenko et al.   MOLECULAR BIOLOGY

Regulatory effect of nerve growth factor in α9β1 integrin–dependent progression of glioblastoma

(2008) Meghan C. Brown et al.   NEURO-ONCOLOGY