Modeling the Role of Wnt Signaling in Human and Drosophila Stem Cells

The WNT target SP5 negatively regulates WNT transcriptional programs in human pluripotent stem cells

(2017) Ian J. Huggins et al.   Nature Communications

Coupling optogenetics and light-sheet microscopy, a method to study Wnt signaling during embryogenesis

(2017) Prameet Kaur et al.   Scientific Reports

Intestinal stem cell overproliferation resulting from inactivation of the APC tumor suppressor requires the transcription cofactors Earthbound and Erect wing

(2017) Ai Tian et al.   PLoS Genetics

Probing the canonicity of the Wnt/Wingless signaling pathway

(2017) Alexandra Franz et al.   PLoS Genetics

Decoding temporal interpretation of the morphogen Bicoid in the early Drosophila embryo

(2017) Anqi Huang et al.   eLife

An embryonic system to assess direct and indirect Wnt transcriptional targets

(2017) Jahnavi Suresh et al.   Scientific Reports

In Vivo Amelioration of Age-Associated Hallmarks by Partial Reprogramming

(2016) Alejandro Ocampo et al.   CELL

Cellular Metabolism and Induced Pluripotency

(2016) Jun Wu et al.   CELL

The Wnt pathway limits BMP signaling outside of the germline stem cell niche in Drosophila ovaries

(2016) Violaine I. Mottier-Pavie et al.   DEVELOPMENTAL BIOLOGY

Gastrointestinal stem cells in health and disease: from flies to humans

(2016) Hongjie Li et al.   Disease Models & Mechanisms

Looking to the future following 10 years of induced pluripotent stem cell technologies

(2016) Mo Li et al.   Nature Protocols

Effective knockdown ofDrosophilalong non-coding RNAs by CRISPR interference

(2016) Sanjay Ghosh et al.   NUCLEIC ACIDS RESEARCH

Axin2marks quiescent hair follicle bulge stem cells that are maintained by autocrine Wnt/β-catenin signaling

(2016) Xinhong Lim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Developmental Drift and the Role of Wnt Signaling in Aging

(2016) Jan Gruber et al.   Cancers

The R-spondin/Lgr5/Rnf43 module: regulator of Wnt signal strength

(2014) W. de Lau et al.   GENES & DEVELOPMENT

Identification of multipotent mammary stem cells by protein C receptor expression

(2014) Daisong Wang et al.   NATURE

An integral program for tissue renewal and regeneration: Wnt signaling and stem cell control

(2014) H. Clevers et al.   SCIENCE

A membrane-associated  -catenin/Oct4 complex correlates with ground-state pluripotency in mouse embryonic stem cells

(2013) F. Faunes et al.   DEVELOPMENT

In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration

(2013) Meritxell Huch et al.   NATURE

Interfollicular Epidermal Stem Cells Self-Renew via Autocrine Wnt Signaling

(2013) X. Lim et al.   SCIENCE

Mammalian genes induce partially reprogrammed pluripotent stem cells in non-mammalian vertebrate and invertebrate species

(2013) Ricardo Antonio Rosselló et al.   eLife

Developmental Stage and Time Dictate the Fate of Wnt/β-Catenin-Responsive Stem Cells in the Mammary Gland

(2012) Renée van Amerongen et al.   Cell Stem Cell

ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner

(2012) Huai-Xiang Hao et al.   NATURE

β-Catenin Enhances Oct-4 Activity and Reinforces Pluripotency through a TCF-Independent Mechanism

(2011) Kevin F. Kelly et al.   Cell Stem Cell

Differential requirement for the dual functions of β-catenin in embryonic stem cell self-renewal and germ layer formation

(2011) Natalia Lyashenko et al.   NATURE CELL BIOLOGY

Embryonic stem cells require Wnt proteins to prevent differentiation to epiblast stem cells

(2011) Derk ten Berge et al.   NATURE CELL BIOLOGY

Inhibition of glycogen synthase kinase-3 alleviates Tcf3 repression of the pluripotency network and increases embryonic stem cell resistance to differentiation

(2011) Jason Wray et al.   NATURE CELL BIOLOGY

A PiggyBac-Based Recessive Screening Method to Identify Pluripotency Regulators

(2011) Ge Guo et al.   PLoS One

Complex Interactions between GSK3 and aPKC in Drosophila Embryonic Epithelial Morphogenesis

(2011) Nicole A. Kaplan et al.   PLoS One

Wnt Proteins Are Self-Renewal Factors for Mammary Stem Cells and Promote Their Long-Term Expansion in Culture

(2010) Yi Arial Zeng et al.   Cell Stem Cell

Intestinal Stem Cells in Mammals and Drosophila

(2009) Andreu Casali et al.   Cell Stem Cell

Towards an integrated view of Wnt signaling in development

(2009) R. van Amerongen et al.   DEVELOPMENT

Selective plane illumination microscopy techniques in developmental biology

(2009) J. Huisken et al.   DEVELOPMENT

Non-cell-autonomous stimulation of stem cell proliferation following ablation of Tcf3

(2009) Fei Yi et al.   EXPERIMENTAL CELL RESEARCH

Wnt signaling pathways meet Rho GTPases

(2009) K. Schlessinger et al.   GENES & DEVELOPMENT

Epithelial Polarity: Interactions Between Junctions and Apical-Basal Machinery

(2009) N. A. Kaplan et al.   GENETICS

Connecting microRNA Genes to the Core Transcriptional Regulatory Circuitry of Embryonic Stem Cells

(2008) Alexander Marson et al.   CELL

Wnt signaling and stem cell control

(2008) Roel Nusse   CELL RESEARCH

Proliferative control in Drosophila stem cells

(2008) Alexander Kohlmaier et al.   CURRENT OPINION IN CELL BIOLOGY

Tcf3 is an integral component of the core regulatory circuitry of embryonic stem cells

(2008) M. F. Cole et al.   GENES & DEVELOPMENT

The behaviour of Drosophila adult hindgut stem cells is controlled by Wnt and Hh signalling

(2008) Shigeo Takashima et al.   NATURE

T-Cell Factor 3 Regulates Embryonic Stem Cell Pluripotency and Self-Renewal by the Transcriptional Control of Multiple Lineage Pathways

(2008) Wai-Leong Tam et al.   STEM CELLS

Tcf3 Functions as a Steady-State Limiter of Transcriptional Programs of Mouse Embryonic Stem Cell Self-Renewal

(2008) Fei Yi et al.   STEM CELLS

Promotion of Reprogramming to Ground State Pluripotency by Signal Inhibition

(2008) Jose Silva et al.   PLOS BIOLOGY