标题
Import and Export of Misfolded α-Synuclein
作者
关键词
-
出版物
Frontiers in Neuroscience
Volume 12, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2018-05-23
DOI
10.3389/fnins.2018.00344
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Selective imaging of internalized proteopathic α-synuclein seeds in primary neurons reveals mechanistic insight into transmission of synucleinopathies
- (2017) Richard J. Karpowicz et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Chaperone-mediated autophagy and endosomal microautophagy: Jointed by a chaperone
- (2017) Kumsal Tekirdag et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Extensive uptake of α-synuclein oligomers in astrocytes results in sustained intracellular deposits and mitochondrial damage
- (2017) Veronica Lindström et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- In vitro α-synuclein neurotoxicity and spreading among neurons and astrocytes using Lewy body extracts from Parkinson disease brains
- (2017) Fabio Cavaliere et al. NEUROBIOLOGY OF DISEASE
- Pathways of Unconventional Protein Secretion
- (2017) Catherine Rabouille TRENDS IN CELL BIOLOGY
- Investigation of Endocytic Pathways for the Internalization of Exosome-Associated Oligomeric Alpha-Synuclein
- (2017) Marion Delenclos et al. Frontiers in Neuroscience
- α-synuclein transfer through tunneling nanotubes occurs in SH-SY5Y cells and primary brain pericytes from Parkinson’s disease patients
- (2017) Birger Victor Dieriks et al. Scientific Reports
- Cellular internalization of alpha-synuclein aggregates by cell surface heparan sulfate depends on aggregate conformation and cell type
- (2017) Elisabet Ihse et al. Scientific Reports
- Axonal transport and secretion of fibrillar forms of α-synuclein, Aβ42 peptide and HTTExon 1
- (2016) Michel Brahic et al. ACTA NEUROPATHOLOGICA
- Tunneling nanotubes spread fibrillar α‐synuclein by intercellular trafficking of lysosomes
- (2016) Saïda Abounit et al. EMBO JOURNAL
- DnaJ/Hsc70 chaperone complexes control the extracellular release of neurodegenerative‐associated proteins
- (2016) Sarah N Fontaine et al. EMBO JOURNAL
- Cellular proteostasis: degradation of misfolded proteins by lysosomes
- (2016) M. P. Jackson et al. Essays in Biochemistry
- The Effect of Fragmented Pathogenic α-Synuclein Seeds on Prion-like Propagation
- (2016) Airi Tarutani et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Widespread transneuronal propagation of α-synucleinopathy triggered in olfactory bulb mimics prodromal Parkinson’s disease
- (2016) Nolwen L. Rey et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Proteolysis of α-synuclein fibrils in the lysosomal pathway limits induction of inclusion pathology
- (2016) Amanda N. Sacino et al. JOURNAL OF NEUROCHEMISTRY
- Unconventional secretion of misfolded proteins promotes adaptation to proteasome dysfunction in mammalian cells
- (2016) Jin-Gu Lee et al. NATURE CELL BIOLOGY
- Pathological -synuclein transmission initiated by binding lymphocyte-activation gene 3
- (2016) X. Mao et al. SCIENCE
- Mesenchymal Stem Cells Inhibit Transmission of α-Synuclein by Modulating Clathrin-Mediated Endocytosis in a Parkinsonian Model
- (2016) Se Hee Oh et al. Cell Reports
- ER Stress and Autophagic Perturbations Lead to Elevated Extracellular α-Synuclein in GBA-N370S Parkinson's iPSC-Derived Dopamine Neurons
- (2016) Hugo J.R. Fernandes et al. Stem Cell Reports
- Direct Observation of α-Synuclein Amyloid Aggregates in Endocytic Vesicles of Neuroblastoma Cells
- (2016) Mihaela M. Apetri et al. PLoS One
- Age-dependent defects of alpha-synuclein oligomer uptake in microglia and monocytes
- (2015) Corinna Bliederhaeuser et al. ACTA NEUROPATHOLOGICA
- Secretory autophagy
- (2015) Marisa Ponpuak et al. CURRENT OPINION IN CELL BIOLOGY
- Extracellular vesicles shuffling intercellular messages: for good or for bad
- (2015) Alessandra Lo Cicero et al. CURRENT OPINION IN CELL BIOLOGY
- -synuclein assemblies sequester neuronal 3-Na+/K+-ATPase and impair Na+ gradient
- (2015) A. N. Shrivastava et al. EMBO JOURNAL
- Effects of Serine 129 Phosphorylation on α-Synuclein Aggregation, Membrane Association, and Internalization
- (2015) Filsy Samuel et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- α-Synuclein strains cause distinct synucleinopathies after local and systemic administration
- (2015) W. Peelaerts et al. NATURE
- Autophagy modulates SNCA/α-synuclein release, thereby generating a hostile microenvironment
- (2014) Anne-Maria Poehler et al. Autophagy
- Defined α-synuclein prion-like molecular assemblies spreading in cell culture
- (2014) Suzana Aulić et al. BMC NEUROSCIENCE
- Lys-63-linked Ubiquitination by E3 Ubiquitin Ligase Nedd4-1 Facilitates Endosomal Sequestration of Internalized α-Synuclein
- (2014) Naoto Sugeno et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- ATP13A2/PARK9 Regulates Secretion of Exosomes and -Synuclein
- (2014) T. Tsunemi et al. JOURNAL OF NEUROSCIENCE
- Addition of exogenous α-synuclein preformed fibrils to primary neuronal cultures to seed recruitment of endogenous α-synuclein to Lewy body and Lewy neurite–like aggregates
- (2014) Laura A Volpicelli-Daley et al. Nature Protocols
- α-Synuclein Immunotherapy Blocks Uptake and Templated Propagation of Misfolded α-Synuclein and Neurodegeneration
- (2014) Hien T. Tran et al. Cell Reports
- Transfer of human α-synuclein from the olfactory bulb to interconnected brain regions in mice
- (2013) Nolwen L. Rey et al. ACTA NEUROPATHOLOGICA
- Boosting chaperone-mediated autophagy in vivo mitigates α-synuclein-induced neurodegeneration
- (2013) Maria Xilouri et al. BRAIN
- Alpha-synuclein transfers from neurons to oligodendrocytes
- (2013) Juan F. Reyes et al. GLIA
- Tubulin Polymerization-promoting Protein (TPPP/p25α) Promotes Unconventional Secretion of α-Synuclein through Exophagy by Impairing Autophagosome-Lysosome Fusion
- (2013) Patrick Ejlerskov et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Lewy Body-like α-Synuclein Aggregates Resist Degradation and Impair Macroautophagy
- (2013) Selcuk A. Tanik et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The autophagosome: origins unknown, biogenesis complex
- (2013) Christopher A. Lamb et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Alpha-Synuclein Induces Lysosomal Rupture and Cathepsin Dependent Reactive Oxygen Species Following Endocytosis
- (2013) David Freeman et al. PLoS One
- Transmission of multiple system atrophy prions to transgenic mice
- (2013) J. C. Watts et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds
- (2013) B. B. Holmes et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structural and functional characterization of two alpha-synuclein strains
- (2013) Luc Bousset et al. Nature Communications
- Neuron-to-neuron transmission of α-synuclein fibrils through axonal transport
- (2012) Eric C. Freundt et al. ANNALS OF NEUROLOGY
- Alpha-synuclein aggregation involves a bafilomycin A1-sensitive autophagy pathway
- (2012) Jochen Klucken et al. Autophagy
- Spatiotemporal Dynamics of Adenovirus Membrane Rupture and Endosomal Escape
- (2012) O. Maier et al. JOURNAL OF VIROLOGY
- Suppression of dynamin GTPase decreases α-synuclein uptake by neuronal and oligodendroglial cells: a potent therapeutic target for synucleinopathy
- (2012) Masatoshi Konno et al. Molecular Neurodegeneration
- Exosomal cell-to-cell transmission of alpha synuclein oligomers
- (2012) Karin M Danzer et al. Molecular Neurodegeneration
- Microautophagy of Cytosolic Proteins by Late Endosomes
- (2011) Ranjit Sahu et al. DEVELOPMENTAL CELL
- Endosome maturation
- (2011) Jatta Huotari et al. EMBO JOURNAL
- Exosome-associated Tau Is Secreted in Tauopathy Models and Is Selectively Phosphorylated in Cerebrospinal Fluid in Early Alzheimer Disease
- (2011) Sudad Saman et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Exogenous α-Synuclein Fibrils Induce Lewy Body Pathology Leading to Synaptic Dysfunction and Neuron Death
- (2011) Laura A. Volpicelli-Daley et al. NEURON
- The AAA-ATPase VPS4 Regulates Extracellular Secretion and Lysosomal Targeting of α-Synuclein
- (2011) Takafumi Hasegawa et al. PLoS One
- Heat-shock protein 70 modulates toxic extracellular α-synuclein oligomers and rescues trans-synaptic toxicity
- (2010) Karin M. Danzer et al. FASEB JOURNAL
- Lysosomal Degradation of α-Synucleinin Vivo
- (2010) Sally K. Mak et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Direct Transfer of α-Synuclein from Neuron to Astroglia Causes Inflammatory Responses in Synucleinopathies
- (2010) He-Jin Lee et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A novel, high-efficiency cellular model of fibrillar α-synuclein inclusions and the examination of mutations that inhibit amyloid formation
- (2010) Elisa A. Waxman et al. JOURNAL OF NEUROCHEMISTRY
- Non-classical exocytosis of α-synuclein is sensitive to folding states and promoted under stress conditions
- (2010) Ara Jang et al. JOURNAL OF NEUROCHEMISTRY
- Selective Molecular Alterations in the Autophagy Pathway in Patients with Lewy Body Disease and in Models of α-Synucleinopathy
- (2010) Leslie Crews et al. PLoS One
- Metabolic Activity Determines Efficacy of Macroautophagic Clearance of Pathological Oligomeric α-Synuclein
- (2009) Wai Haung Yu et al. AMERICAN JOURNAL OF PATHOLOGY
- Galectin-3, a marker for vacuole lysis by invasive pathogens
- (2009) Irit Paz et al. CELLULAR MICROBIOLOGY
- On the mechanism of internalization of α-synuclein into microglia: roles of ganglioside GM1 and lipid raft
- (2009) Ji-Young Park et al. JOURNAL OF NEUROCHEMISTRY
- Beclin 1 Gene Transfer Activates Autophagy and Ameliorates the Neurodegenerative Pathology in -Synuclein Models of Parkinson's and Lewy Body Diseases
- (2009) B. Spencer et al. JOURNAL OF NEUROSCIENCE
- Inclusion formation and neuronal cell death through neuron-to-neuron transmission of -synuclein
- (2009) P. Desplats et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Exogenous -synuclein fibrils seed the formation of Lewy body-like intracellular inclusions in cultured cells
- (2009) K. C. Luk et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Clearance and deposition of extracellular α-synuclein aggregates in microglia
- (2008) He-Jin Lee et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Molecular mechanisms of α-synuclein neurodegeneration
- (2008) Elisa A. Waxman et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Microglial phagocytosis is enhanced by monomeric α-synuclein, not aggregated α-synuclein: Implications for Parkinson's disease
- (2008) Ji-Young Park et al. GLIA
- Assembly-dependent endocytosis and clearance of extracellular a-synuclein
- (2008) He-Jin Lee et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Wild Type α-Synuclein Is Degraded by Chaperone-mediated Autophagy and Macroautophagy in Neuronal Cells
- (2008) Tereza Vogiatzi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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