Tomosyn functions as a PKCδ-regulated fusion clamp in mast cell degranulation

Munc13-4 functions as a Ca2+ sensor for homotypic secretory granule fusion to generate endosomal exocytic vacuoles

(2017) Sang Su Woo et al.   MOLECULAR BIOLOGY OF THE CELL

The Mast Cell-IgE Paradox

(2016) Stephen J. Galli   AMERICAN JOURNAL OF PATHOLOGY

Phosphorylation of syntaxin-3 at Thr 14 negatively regulates exocytosis in RBL-2H3 mast cells

(2016) Satoshi Tadokoro et al.   CELL BIOLOGY INTERNATIONAL

Phosphorylation of residues inside the SNARE complex suppresses secretory vesicle fusion

(2016) Seth Malmersjö et al.   EMBO JOURNAL

Elevated total serum immunoglobulin E (>1000 IU/mL): implications?

(2016) T. R. Tay et al.   INTERNAL MEDICINE JOURNAL

Kinesin-1 controls mast cell degranulation and anaphylaxis through PI3K-dependent recruitment to the granular Slp3/Rab27b complex

(2016) Isabelle Munoz et al.   JOURNAL OF CELL BIOLOGY

Rab12 Regulates Retrograde Transport of Mast Cell Secretory Granules by Interacting with the RILP–Dynein Complex

(2016) Adi Efergan et al.   JOURNAL OF IMMUNOLOGY

Dynamic Partitioning of Synaptic Vesicle Pools by the SNARE-Binding Protein Tomosyn

(2016) V. A. Cazares et al.   JOURNAL OF NEUROSCIENCE

The importance of EN ISO 15189 accreditation of allergen-specific IgE determination for reliablein vitroallergy diagnosis

(2015) C. Lambert et al.   ALLERGY

Tomosyn is a novel Akt substrate mediating insulin-dependent GLUT4 exocytosis

(2015) Koki Nagano et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Structural basis for recognition of the Sec4 Rab GTPase by its effector, the Lgl/tomosyn homologue, Sro7

(2015) Kelly Watson et al.   MOLECULAR BIOLOGY OF THE CELL

International Consensus on drug allergy

(2014) P. Demoly et al.   ALLERGY

Mechanisms Controlling Mast Cell and Basophil Lineage Decisions

(2014) Hua Huang et al.   CURRENT ALLERGY AND ASTHMA REPORTS

Differential Interaction of Tomosyn with Syntaxin and SNAP25 Depends on Domains in the WD40 β-Propeller Core and Determines Its Inhibitory Activity

(2014) Noa Bielopolski et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The N- and C-terminal Domains of Tomosyn Play Distinct Roles in SolubleN-Ethylmaleimide-sensitive Factor Attachment Protein Receptor Binding and Fusion Regulation

(2014) Haijia Yu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphorylation and Degradation of Tomosyn-2 De-represses Insulin Secretion

(2014) Sushant Bhatnagar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Platelet secretion and hemostasis require syntaxin-binding protein STXBP5

(2014) Shaojing Ye et al.   JOURNAL OF CLINICAL INVESTIGATION

Syntaxin-binding protein STXBP5 inhibits endothelial exocytosis and promotes platelet secretion

(2014) Qiuyu Zhu et al.   JOURNAL OF CLINICAL INVESTIGATION

Doc2  and Munc13-4 Regulate Ca2+-Dependent Secretory Lysosome Exocytosis in Mast Cells

(2014) H. Higashio et al.   JOURNAL OF IMMUNOLOGY

Rab5 Is a Novel Regulator of Mast Cell Secretory Granules: Impact on Size, Cargo, and Exocytosis

(2014) N. P. Azouz et al.   JOURNAL OF IMMUNOLOGY

Phosphorylation of syntaxin 3B by CaMKII regulates the formation of t-SNARE complexes

(2014) Xiaoqin Liu et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Vesicular Trafficking and Signaling for Cytokine and Chemokine Secretion in Mast Cells

(2014) Ulrich Blank et al.   Frontiers in Immunology

International consensus on (ICON) anaphylaxis

(2014) F Estelle R Simons et al.   World Allergy Organization Journal

Intracellular trafficking and secretion of inflammatory cytokines

(2013) Jennifer L. Stow et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Munc18-2 and Syntaxin 3 Control Distinct Essential Steps in Mast Cell Degranulation

(2013) C. Brochetta et al.   JOURNAL OF IMMUNOLOGY

Crucial role of the hydrophobic pocket region of Munc18 protein in mast cell degranulation

(2013) N.-R. Bin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protein kinase C (PKC) isozyme-specific substrates and their design

(2012) Jeong-Hun Kang et al.   BIOTECHNOLOGY ADVANCES

ICON: Food allergy

(2012) A. Wesley Burks et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Structural and Functional Analysis of Tomosyn Identifies Domains Important in Exocytotic Regulation

(2011) Antionette L. Williams et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tomosyn-dependent regulation of synaptic transmission is required for a late phase of associative odor memory

(2011) K. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tomosyn Inhibits Synaptotagmin-1-mediated Step of Ca2+-dependent Neurotransmitter Release through Its N-terminal WD40 Repeats

(2010) Yasunori Yamamoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lyn, PKC- , SHIP-1 interactions regulate GPVI-mediated platelet-dense granule secretion

(2009) R. Chari et al.   BLOOD

Complexin II regulates degranulation in RBL-2H3 cells by interacting with SNARE complex containing syntaxin-3

(2009) Satoshi Tadokoro et al.   CELLULAR IMMUNOLOGY

Reciprocal Intramolecular Interactions of Tomosyn Control Its Inhibitory Activity on SNARE Complex Formation

(2009) Yasunori Yamamoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Synaptotagmin-2 Controls Regulated Exocytosis but Not Other Secretory Responses of Mast Cells

(2009) Ernestina Melicoff et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Friends and foes in synaptic transmission: the role of tomosyn in vesicle priming

(2009) Uri Ashery et al.   TRENDS IN NEUROSCIENCES

Involvement of Munc18 isoforms in the regulation of granule exocytosis in neutrophils

(2008) Cristiana Brochetta et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

VAMP-8 segregates mast cell-preformed mediator exocytosis from cytokine trafficking pathways

(2008) N. Tiwari et al.   BLOOD

Membrane traffic in the secretory pathway

(2008) J. Malsam et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Dual inhibition of SNARE complex formation by tomosyn ensures controlled neurotransmitter release

(2008) Toshiaki Sakisaka et al.   JOURNAL OF CELL BIOLOGY

The development of allergic inflammation

(2008) Stephen J. Galli et al.   NATURE

Mast cells possess distinct secretory granule subsets whose exocytosis is regulated by different SNARE isoforms

(2008) N. Puri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA