Global assessment of its network dynamics reveals that the kinase Plk1 inhibits the phosphatase PP6 to promote Aurora A activity

JIP4 is a PLK1 binding protein that regulates p38MAPK activity in G2 phase

(2015) Alex Pinder et al.   CELLULAR SIGNALLING

Quantitative phosphoproteomics reveals new roles for the protein phosphatase PP6 in mitotic cells

(2015) Scott F. Rusin et al.   Science Signaling

Quantitative phosphoproteomics reveals new roles for the protein phosphatase PP6 in mitotic cells

(2015) Scott F. Rusin et al.   Science Signaling

The CRAPome: a contaminant repository for affinity purification–mass spectrometry data

(2013) Dattatreya Mellacheruvu et al.   NATURE METHODS

Protein Interaction Network of the Mammalian Hippo Pathway Reveals Mechanisms of Kinase-Phosphatase Interactions

(2013) A. L. Couzens et al.   Science Signaling

Rapid Determination of Multiple Linear Kinase Substrate Motifs by Mass Spectrometry

(2012) Arminja N. Kettenbach et al.   CHEMISTRY & BIOLOGY

PP6 Regulatory Subunit R1 Is Bidentate Anchor for Targeting Protein Phosphatase-6 to DNA-dependent Protein Kinase

(2012) Amol S. Hosing et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Plk1 regulates the kinesin-13 protein Kif2b to promote faithful chromosome segregation

(2012) Emily A. Hood et al.   MOLECULAR BIOLOGY OF THE CELL

A travel guide to Cytoscape plugins

(2012) Rintaro Saito et al.   NATURE METHODS

Comet: An open-source MS/MS sequence database search tool

(2012) Jimmy K. Eng et al.   PROTEOMICS

Switching Polo-like kinase-1 on and off in time and space

(2012) Wytse Bruinsma et al.   TRENDS IN BIOCHEMICAL SCIENCES

How protein kinases co-ordinate mitosis in animal cells

(2011) Hoi Tang Ma et al.   BIOCHEMICAL JOURNAL

Protein phosphatases and the regulation of mitosis

(2011) F. A. Barr et al.   JOURNAL OF CELL SCIENCE

Combination of Chemical Genetics and Phosphoproteomics for Kinase Signaling Analysis Enables Confident Identification of Cellular Downstream Targets

(2011) Felix S. Oppermann et al.   MOLECULAR & CELLULAR PROTEOMICS

Quantitative Phospho-proteomics to Investigate the Polo-like Kinase 1-Dependent Phospho-proteome

(2011) Karin Grosstessner-Hain et al.   MOLECULAR & CELLULAR PROTEOMICS

Global quantification of mammalian gene expression control

(2011) Björn Schwanhäusser et al.   NATURE

Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity

(2011) Theonie Anastassiadis et al.   NATURE BIOTECHNOLOGY

Phosphatases: providing safe passage through mitotic exit

(2011) Claudia Wurzenberger et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Switches and latches: a biochemical tug-of-war between the kinases and phosphatases that control mitosis

(2011) M. R. Domingo-Sananes et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

MassChroQ: A versatile tool for mass spectrometry quantification

(2011) Benoît Valot et al.   PROTEOMICS

Quantitative Phosphoproteomics Identifies Substrates and Functional Modules of Aurora and Polo-Like Kinase Activities in Mitotic Cells

(2011) A. N. Kettenbach et al.   Science Signaling

Boosting and suppressing mitotic phosphorylation

(2011) René H. Medema et al.   TRENDS IN BIOCHEMICAL SCIENCES

Astrin regulates meiotic spindle organization, spindle pole tethering and cell cycle progression in mouse oocytes

(2010) Ju Yuan et al.   CELL CYCLE

Mitotic Inhibition of GRASP65 Organelle Tethering Involves Polo-like Kinase 1 (PLK1) Phosphorylation Proximate to an Internal PDZ Ligand

(2010) Debrup Sengupta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cdk1 Activity Is Required for Mitotic Activation of Aurora A during G2/M Transition of Human Cells

(2010) Robert D. Van Horn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protein phosphatase 6 regulates mitotic spindle formation by controlling the T-loop phosphorylation state of Aurora A bound to its activator TPX2

(2010) Kang Zeng et al.   JOURNAL OF CELL BIOLOGY

The Plk1-dependent Phosphoproteome of the Early Mitotic Spindle

(2010) Anna Santamaria et al.   MOLECULAR & CELLULAR PROTEOMICS

SAINT: probabilistic scoring of affinity purification–mass spectrometry data

(2010) Hyungwon Choi et al.   NATURE METHODS

A Mitotic Phosphorylation Feedback Network Connects Cdk1, Plk1, 53BP1, and Chk2 to Inactivate the G2/M DNA Damage Checkpoint

(2010) Marcel A. T. M. van Vugt et al.   PLOS BIOLOGY

Mapping of protein phosphatase-6 association with its SAPS domain regulatory subunit using a model of helical repeats

(2009) Julien Guergnon et al.   BMC BIOCHEMISTRY

Discovery and Exploitation of Inhibitor-resistant Aurora and Polo Kinase Mutants for the Analysis of Mitotic Networks

(2009) Paul J. Scutt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Polo-like kinases: conservation and divergence in their functions and regulation

(2009) Vincent Archambault et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Protein Phosphatase 6 Regulatory Subunits Composed of Ankyrin Repeat Domains†

(2008) Bjarki Stefansson et al.   BIOCHEMISTRY

Plk1 regulates mitotic Aurora A function through βTrCP-dependent degradation of hBora

(2008) Eunice H. Y. Chan et al.   CHROMOSOMA

Polo on the Rise—from Mitotic Entry to Cytokinesis with Plk1

(2008) Mark Petronczki et al.   DEVELOPMENTAL CELL

Polo-like kinase-1 is activated by aurora A to promote checkpoint recovery

(2008) Libor Macůrek et al.   NATURE

The GOA database in 2009--an integrated Gene Ontology Annotation resource

(2008) D. Barrell et al.   NUCLEIC ACIDS RESEARCH

Bora and the Kinase Aurora A Cooperatively Activate the Kinase Plk1 and Control Mitotic Entry

(2008) A. Seki et al.   SCIENCE