Inactivating mutations in Drosha mediate vascular abnormalities similar to hereditary hemorrhagic telangiectasia

Bone Morphogenetic Proteins in Vascular Homeostasis and Disease

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Let-7 microRNA-dependent control of leukotriene signaling regulates the transition of hematopoietic niche in mice

(2017) Xuan Jiang et al.   Nature Communications

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Multipotency of Adult Hippocampal NSCs In Vivo Is Restricted by Drosha/NFIB

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Endothelial notch signaling is essential to prevent hepatic vascular malformations in mice

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TGF-β Signaling from Receptors to Smads

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ZO-1 controls endothelial adherens junctions, cell–cell tension, angiogenesis, and barrier formation

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(2015) Jamie McDonald et al.   Frontiers in Genetics

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(2014) Minju Ha et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Somatic mutations in DROSHA and DICER1 impair microRNA biogenesis through distinct mechanisms in Wilms tumours

(2014) Dinesh Rakheja et al.   Nature Communications

Recurrent somatic mutation in DROSHA induces microRNA profile changes in Wilms tumour

(2014) Giovana T. Torrezan et al.   Nature Communications

Causal analysis approaches in Ingenuity Pathway Analysis

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Mammalian 5′-Capped MicroRNA Precursors that Generate a Single MicroRNA

(2013) Mingyi Xie et al.   CELL

Deep sequencing of small RNAs identifies canonical and non-canonical miRNA and endogenous siRNAs in mammalian somatic tissues

(2013) Leandro Castellano et al.   NUCLEIC ACIDS RESEARCH

Drosha Regulates Gene Expression Independently of RNA Cleavage Function

(2013) Natalia Gromak et al.   Cell Reports

Poly(A)-Specific Ribonuclease Mediates 3′-End Trimming of Argonaute2-Cleaved Precursor MicroRNAs

(2013) Mayuko Yoda et al.   Cell Reports

Angiogenesis regulation by TGFβ signalling: clues from an inherited vascular disease

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Hereditary hemorrhagic telangiectasia: An overview of diagnosis, management, and pathogenesis

(2011) Jamie McDonald et al.   GENETICS IN MEDICINE

Cranial vasculature in zebrafish forms by angioblast cluster-derived angiogenesis

(2010) Kira Proulx et al.   DEVELOPMENTAL BIOLOGY

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

(2010) A. McKenna et al.   GENOME RESEARCH

Update on molecular diagnosis of hereditary hemorrhagic telangiectasia

(2010) Jennifer Richards-Yutz et al.   HUMAN GENETICS

Hereditary hemorrhagic telangiectasia: from molecular biology to patient care

(2010) S. DUPUIS-GIROD et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Smad Proteins Bind a Conserved RNA Sequence to Promote MicroRNA Maturation by Drosha

(2010) Brandi N. Davis et al.   MOLECULAR CELL

Constitutively active endothelial Notch4 causes lung arteriovenous shunts in mice

(2009) Doug Miniati et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

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(2009) H. Li et al.   BIOINFORMATICS

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

DLL1-mediated Notch activation regulates endothelial identity in mouse fetal arteries

(2009) I. Sorensen et al.   BLOOD

Posttranscriptional Crossregulation between Drosha and DGCR8

(2009) Jinju Han et al.   CELL

Real-time imaging of de novo arteriovenous malformation in a mouse model of hereditary hemorrhagic telangiectasia

(2009) Sung Ok Park et al.   JOURNAL OF CLINICAL INVESTIGATION

Runx1 is required for the endothelial to haematopoietic cell transition but not thereafter

(2009) Michael J. Chen et al.   NATURE

miR-126 Regulates Angiogenic Signaling and Vascular Integrity

(2008) Jason E. Fish et al.   DEVELOPMENTAL CELL

The RNAseIII enzyme Drosha is critical in T cells for preventing lethal inflammatory disease

(2008) Mark M.W. Chong et al.   JOURNAL OF EXPERIMENTAL MEDICINE

SMAD proteins control DROSHA-mediated microRNA maturation

(2008) Brandi N. Davis et al.   NATURE

ALK5- and TGFBR2-independent role of ALK1 in the pathogenesis of hereditary hemorrhagic telangiectasia type 2

(2007) S. O. Park et al.   BLOOD