Review
Engineering, Multidisciplinary
Ansheed A. Raheem, Pearlin Hameed, Ruban Whenish, Renold S. Elsen, G. Aswin, Amit Kumar Jaiswal, Konda Gokuldoss Prashanth, Geetha Manivasagam
Summary: Biomimetics is a field that adapts principles from nature to fine-tune engineering designs to mimic biological structures and functions, mainly focusing on medical implants. Additive manufacturing, with its layer-by-layer construction, allows finer control over material placement, overcoming design challenges from conventional manufacturing methods. This review highlights the use of additive manufacturing in biomimetic 3D printing of ceramic, polymer, and metal implants closely resembling natural tissues.
Review
Engineering, Manufacturing
Ashish Kalkal, Sumit Kumar, Pramod Kumar, Rangadhar Pradhan, Magnus Willander, Gopinath Packirisamy, Saurabh Kumar, Bansi Dhar Malhotra
Summary: Three-dimensional (3D) printing technologies are driving the development of wearable (bio)sensors with exciting characteristics such as high stretchability, super flexibility, low cost, ultra-thinness, and lightweight. This advanced manufacturing technology has revolutionized the concept of free form construction and end-user customization, leading to the fabrication of smaller, faster, and more efficient wearable devices. The contribution of 3D printing in developing novel structures for wearable applications using printable soft and functional materials is highlighted, along with the summary of major printing techniques and various (bio)sensing platforms discussed in terms of design specifications and fabrication strategies.
ADDITIVE MANUFACTURING
(2021)
Review
Pharmacology & Pharmacy
Humira Assad, Arvina Assad, Ashish Kumar
Summary: The field of 3D bio-printing has been extensively used to improve the usability and performance of scaffolds filled with cells. Many tissues and organs have been produced via 3D bio-printing and can serve as building blocks for repair and regeneration, as well as in vitro models for pharmacokinetics and drug screening. The research focuses on novel biomaterials with quick cross-linking capabilities, a wider variety of acceptable 3D-printed materials, better printing resolution, and biomaterial compatibility.
Article
Materials Science, Ceramics
Alberto Boretti, Stefania Castelletto
Summary: The paper provides a comprehensive exploration of 3D printing silicon carbide, discussing its advantages, applications, challenges, and significance. Despite its many advantages, silicon carbide 3D printing still faces several significant challenges.
JOURNAL OF THE EUROPEAN CERAMIC SOCIETY
(2024)
Review
Engineering, Manufacturing
Shakib Hyder Siddique, Paul J. Hazell, Hongxu Wang, Juan P. Escobedo, Ali A. H. Ameri
Summary: This paper explores the potential of biological structures as inspiration for high-performance mechanical structures and discusses the use of additive manufacturing techniques in creating biomimetic porous structures. It also provides a detailed overview of different types of biological porous structures and their engineering applications.
ADDITIVE MANUFACTURING
(2022)
Review
Food Science & Technology
Ezgi Pulatsu, Mengshi Lin
Summary: This review article summarizes recent advances in 3D food printing with a focus on current approaches to define the printability, optimize food ink formulas, mechanisms of AM technology, and suitability of food materials for 3D printing. Systematic manufacturing approach is crucial for understanding the 3DP process, and framing each step in the workflow may simplify research steps and accelerate high-quality 3DP for food applications. Redefining printability and summarizing existing approaches to obtain printable food materials will lay the foundation for future studies in this field.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2021)
Article
Engineering, Mechanical
Yee Ling Yap, William Toh, Anthoni Giam, Feng Rong Yong, Keen Ian Chan, Justin Wei Sheng Tay, Soo Soon Teong, Rongming Lin, Teng Yong Ng
Summary: The increasing popularity of micro-unmanned aerial vehicles (micro-UAVs) among professionals and hobbyists is attributed to the advancement in additive manufacturing technology. Through the use of 3D-printing and topology optimization, ultra-lightweight micro-UAVs can be designed and manufactured without compromising their structural integrity. This article presents the characterization of Nylon 12 (PA12) material properties manufactured using selective laser sintering (SLS) and the application of topology optimization in designing a lightweight micro-quadcopter. The close correlation between numerical and experimental data validates the adoption of topology optimization and 3D printing for the design and rapid prototyping of micro-UAVs.
INTERNATIONAL JOURNAL OF MECHANICAL SCIENCES
(2023)
Article
Materials Science, Paper & Wood
V. C. Agbakoba, T. C. Mokhena, E. E. Ferg, S. P. Hlangothi, M. J. John
Summary: This study focuses on the development of 3D printable bionanocomposites using PLA and CNFs, which exhibit good flexibility and strength. The incorporation of triacetin as a plasticizer eliminates the brittleness of the material. The experimental results show that the composite material has adequate roundness and thermal stability.
Article
Engineering, Chemical
Sinan Yilmaz, Okan Gul, Busra Eyri, N. Gamze Karsli Yilmaz, Taner Yilmaz
Summary: In recent years, there has been an increasing popularity in the use of additive manufacturing technologies, specifically fused deposition modeling (FDM) and 3D printing. Poly(lactic acid) (PLA) is a commonly used material in FDM due to its biodegradability. This study investigates the properties of composite materials made from bamboo-filled PLA filament using FDM. The mechanical, thermal, thermo-mechanical, tribological, and morphological properties of the materials were analyzed.
POLYMER ENGINEERING AND SCIENCE
(2023)
Review
Engineering, Environmental
Jie Zhu, Peiwen Wu, Yanhong Chao, Jiangtao Yu, Wenshuai Zhu, Zhichang Liu, Chunming Xu
Summary: Three-dimensional (3D) printing is revolutionizing the design and manufacturing of 3D objects by transforming digital models into solid models. In the field of catalysis, 3D printing technology offers new possibilities and is widely applied in related catalytic reactions and processes.
CHEMICAL ENGINEERING JOURNAL
(2022)
Review
Polymer Science
Quinten Thijssen, Joseph Toombs, Chi Chung Li, Hayden Taylor, Sandra Van Vlieberghe
Summary: This review comprehensively discusses the potential of volumetric 3D-printing, summarizing the theoretical framework of photopolymerization and highlighting the advancements in light-based 3D-printing techniques. Special attention is given to the subfield of volumetric bioprinting. The review provides important discussions and prospects for those interested in the field of volumetric 3D-printing.
PROGRESS IN POLYMER SCIENCE
(2023)
Article
Engineering, Manufacturing
Qifeng Qian, Jan Henk Kamps, Brian Price, Hao Gu, Ricky Wildman, Richard Hague, Belen Begines, Christopher Tuck
Summary: In this study, a 3D reactive inkjet printing method was developed to successfully fabricate bisphenol A-polycarbonate material, demonstrating the capability to broaden the range of AM materials to include engineering grade polymers.
ADDITIVE MANUFACTURING
(2022)
Review
Engineering, Multidisciplinary
Xin Ning Zhang, Qiang Zheng, Zi Liang Wu
Summary: This paper reviews the recent progress in 3D printing of tough hydrogels and their applications. It provides an overview of the advantages and requirements of tough hydrogel systems for specific 3D printing technologies, and summarizes the network structures, mechanical performances, toughening mechanisms, and representative applications of the printed tough hydrogels. It also discusses the recent advances in 4D printing of tough hydrogels as a prospective direction for soft actuators and robots.
COMPOSITES PART B-ENGINEERING
(2022)
Review
Electrochemistry
Abdul Jabbar Khan, Abdul Mateen, Shaukat Khan, Liang He, Wenwu Wang, Arshid Numan, Kui-Qing Peng, Iftikhar Ahmed Malik, Ijaz Hussain, Guowei Zhao
Summary: This review provides a comprehensive overview of the recent advancements in the applications of 3D printing techniques for micro-electrochemical energy storage devices (MEESDs), including micro-supercapacitors, micro-batteries, and metal-ion hybrid micro-supercapacitors. It discusses the fundamental of 3D printing technology for micro/nano energy storage devices, the properties of printable inks, and the current developments in 3D printing-based MEESDs. The review also addresses the challenges and future prospects of 3D printing based MEESDs, including material limitations, printing resolution, manufacturing scalability, mechanical properties, and cost.
BATTERIES & SUPERCAPS
(2023)
Review
Chemistry, Applied
Arianna Dick, Xiuping Dong, Bhesh Bhandari, Sangeeta Prakash
Summary: This article discusses the impact of food hydrocolloids on the 3D printability of meat products by evaluating key rheological properties at different stages of the process. Thickening agents and gelling agents improve the viscosity of meat paste, aiding in extrusion and shape fidelity.
FOOD HYDROCOLLOIDS
(2021)
Article
Engineering, Electrical & Electronic
Massimo Angeletti, Philippe Renaud, Corrado Gargiulo
Summary: A new type of cooling substrate for future High Energy Physics detectors is presented in this research. By using microchannels and a modular interlocking concept, the mechanical and hydraulic interconnection problem is solved, and the plug-and-play, interchangeability, and sealing performance of the substrates are improved.
MICROELECTRONIC ENGINEERING
(2022)
Article
Biochemical Research Methods
Heloise Hannart, Audrey Berger, Luc Aeberli, David Forchelet, Nicolas Uffer, Georges Muller, Yann Barrandon, Philippe Renaud, David Bonzon
Summary: Single-cell isolation is a transformative tool for understanding biological systems and has important implications for diagnosis, treatment, and personalized medicine. This study presents the transition from impedance-based pipetting technology into an automated instrument, DispenCell-S1, for traceable isolation of single cells. Models predicting the performance of single-cell isolation in 96-well plates were developed and validated, resulting in fast and efficient isolation with high reliability.
Article
Chemistry, Analytical
Joan Teixidor, Salvatore Novello, Daniel Ortiz, Laure Menin, Hilal A. Lashuel, Arnaud Bertsch, Philippe Renaud
Summary: The paper introduces a new Droplet on Demand (DoD) sampling method for collecting molecules from brain extracellular fluid in mice, allowing fast and accurate glucose quantification without transient regimes. This technique has the potential to be valuable for research on neurodegenerative diseases.
ANALYTICAL CHEMISTRY
(2022)
Article
Biotechnology & Applied Microbiology
Clementine Lipp, Laure Koebel, Arnaud Bertsch, Michael Gauthier, Aude Bolopion, Philippe Renaud
Summary: We present a microfluidic dielectrophoretic-actuated system for trapping single cells and forming controlled cell aggregates. We propose a novel method to characterize the efficiency of dielectrophoretic trapping, taking into account both flow speed and heat generated by the traps as limiting factors for safe cell manipulation. Experimental comparison of two original designs with different manufacturing processes identifies the most efficient design, which is validated by monitoring cell membrane integrity using fluorescence imaging. We suggest design rules for adapting the traps to multiple-cell trapping, and experimentally demonstrate the formation of controlled size and composition aggregates using two different cell types. This study provides a simple manufactured tool for the controlled manipulation of particles in the composition of multicellular assemblies.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Physics, Multidisciplinary
Dorian Herle, Philippe Renaud, Olivier Parriaux
Summary: This study explores the reflection switching concept of a free-space wave impinging on an array of dielectric or semiconductor pillars. By splitting the pillars and creating low-index gaps between them, the reflection of the wave can be effectively canceled. The study also designs a gapless experimental model and a pillar structure with nanometer-thick low-index gaps, achieving a broad reflection maximum at a specific wavelength and no reflection peak over a wide wavelength range.
JOURNAL OF PHYSICS COMMUNICATIONS
(2022)
Article
Engineering, Biomedical
Shiva Taheri, Zahra Sadat Ghazali, Leila Montazeri, Fatemeh Ale Ebrahim, Jafar Javadpour, Khorshid Kamguyan, Esben Thormann, Philippe Renaud, Shahin Bonakdar
Summary: The effect of cell imprinted substrates on the differentiation of ADSCs was investigated. The results showed that cell imprinted substrates can induce differentiation signals better than engineered lithographic substrates. Therefore, the patterns must include nano-topographies to have reliable and reproducible engineered substrates.
BIOMEDICAL MATERIALS
(2023)
Article
Biochemistry & Molecular Biology
Fatemeh Navaee, Philippe Renaud, Alexander Kleger, Thomas Braschler
Summary: Biochemical and biophysical properties of cardiac tissue can be manipulated by using a blend of decellularized extracellular matrix (dECM) from porcine ventricular tissue and fibrinogen, which has shown enhanced cardiogenic differentiation and beating motion in a 3D cardiac cell culture model.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Physics, Fluids & Plasmas
Jiande Zhou, Yves-Marie Ducimetiere, Daniel Migliozzi, Ludovic Keiser, Arnaud Bertsch, Francois Gallaire, Philippe Renaud
Summary: This work reports a novel breakup regime in the widely studied T-junction geometry, where the pinch-off occurs laterally in the two outlet channels, leading to the formation of three daughter droplets. It is driven by surface tension, and a design rule for the T-junction geometry is proposed. A model is developed to predict the formation and growth of an underlying carrier fluid pocket that accounts for this lateral breakup mechanism.
PHYSICAL REVIEW FLUIDS
(2023)
Article
Cell Biology
Fatemeh Navaee, Niloofar Khornian, David Longet, Sarah Heub, Stephanie Boder-Pasche, Gilles Weder, Alexander Kleger, Philippe Renaud, Thomas Braschler
Summary: Alignment of cardiomyocytes in myocardium tissue is important for the functions of the myocardium. This paper proposes a simple method to align cells in a 3D in vitro heart model using microfabricated PDMS grooves. The functionality of the model was evaluated by comparing beating rates between aligned and non-aligned structures. This model has potential applications in drug screening, tissue engineering, and heart-on-chip studies.
Article
Biotechnology & Applied Microbiology
Fatemeh Navaee, Philippe Renaud, Niccolo Piacentini, Mathilde Durand, Dara Zaman Bayat, Diane Ledroit, Sarah Heub, Stephanie Boder-Pasche, Alexander Kleger, Thomas Braschler, Gilles Weder
Summary: Myocardium is composed of cardiac cells that interact with their environment and their structure affects the physiology, function, and metabolism of cardiac tissue. This study aims to understand the mechanism of generating off-axis alignments in the myocardium and develop a reliable in vitro cardiac model. By applying cyclic mechanical stimulation and groove constraint, the researchers were able to engineer off-axis alignments similar to the helical arrangements observed in vivo. The study also shows that cyclical stretching supports cell survival and development, improving the model's function.
BIOENGINEERING-BASEL
(2023)
Article
Chemistry, Analytical
Nicolas Maino, Arnaud Bertsch, Philippe Renaud
Summary: For more than 30 years, carbon fiber microelectrodes have been the gold standard for measuring processes at the synaptic level. However, these microelectrodes have limitations in terms of low throughput and detecting molecules due to their featureless nature. In this study, a new electrochemical sensor with insulated protruding volcano-shaped tips is introduced, which allows confined and parallel recordings of exocytosis from adherent cells. The sensor reveals faster exocytosis kinetics, potentially due to the perturbation of the plasma membrane by the sensor's topography, suggesting that substrate geometry can manipulate exocytosis kinetics and open up new avenues for studying synaptic processes.
Article
Biochemical Research Methods
Jiande Zhou, Amaury Wei, Arnaud Bertsch, Philippe Renaud
Summary: The Poisson limit poses a major challenge for isolating single cells, but this article presents a passive microfluidic system that overcomes this limitation with high efficiency. It has a high throughput and low fault ratio, making it suitable for various cells and particles.
Review
Biochemical Research Methods
David P. Taylor, Prerit Mathur, Philippe Renaud, Govind Kaigala
Summary: This review presents methods of using hydrodynamic phenomena to confine biological and chemical species, discussing their utility in life-sciences research. By choosing specific flow regimes and boundary conditions, hydrodynamic confinements can be applied to various functionalities, from cell separation and sorting to bio-printing and clinical diagnosis.