Cryo-EM structure of the adenosine A2A receptor coupled to an engineered heterotrimeric G protein
出版年份 2018 全文链接
标题
Cryo-EM structure of the adenosine A2A receptor coupled to an engineered heterotrimeric G protein
作者
关键词
-
出版物
eLife
Volume 7, Issue -, Pages -
出版商
eLife Sciences Organisation, Ltd.
发表日期
2018-05-03
DOI
10.7554/elife.35946
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Towards high throughput GPCR crystallography: In Meso soaking of Adenosine A2A Receptor crystals
- (2018) Prakash Rucktooa et al. Scientific Reports
- Phase-plate cryo-EM structure of a biased agonist-bound human GLP-1 receptor–Gs complex
- (2018) Yi-Lynn Liang et al. NATURE
- Phase-plate cryo-EM structure of a class B GPCR–G-protein complex
- (2017) Yi-Lynn Liang et al. NATURE
- Cryo-EM structure of the activated GLP-1 receptor in complex with a G protein
- (2017) Yan Zhang et al. NATURE
- MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy
- (2017) Shawn Q Zheng et al. NATURE METHODS
- Crystal structure of the adenosine A2Areceptor bound to an antagonist reveals a potential allosteric pocket
- (2017) Bingfa Sun et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cryo-EM structure of haemoglobin at 3.2 Å determined with the Volta phase plate
- (2017) Maryam Khoshouei et al. Nature Communications
- Recent developments in the CCP-EM software suite
- (2017) Tom Burnley et al. Acta Crystallographica Section D-Structural Biology
- A pipeline approach to single-particle processing inRELION
- (2017) Rafael Fernandez-Leiro et al. Acta Crystallographica Section D-Structural Biology
- Mini-G proteins: Novel tools for studying GPCRs in their active conformation
- (2017) Rony Nehmé et al. PLoS One
- Controlling the Dissociation of Ligands from the Adenosine A2A Receptor through Modulation of Salt Bridge Strength
- (2016) Elena Segala et al. JOURNAL OF MEDICINAL CHEMISTRY
- Gctf: Real-time CTF determination and correction
- (2016) Kai Zhang JOURNAL OF STRUCTURAL BIOLOGY
- Unravelling biological macromolecules with cryo-electron microscopy
- (2016) Rafael Fernandez-Leiro et al. NATURE
- Structure of the adenosine A2A receptor bound to an engineered G protein
- (2016) Byron Carpenter et al. NATURE
- Engineering a minimal G protein to facilitate crystallisation of G protein-coupled receptors in their active conformation
- (2016) Byron Carpenter et al. PROTEIN ENGINEERING DESIGN & SELECTION
- Single particle electron cryomicroscopy: trends, issues and future perspective
- (2016) Kutti R. Vinothkumar et al. QUARTERLY REVIEWS OF BIOPHYSICS
- Accelerated cryo-EM structure determination with parallelisation using GPUs in RELION-2
- (2016) Dari Kimanius et al. eLife
- Semi-automated selection of cryo-EM particles in RELION-1.3
- (2015) Sjors H.W. Scheres JOURNAL OF STRUCTURAL BIOLOGY
- EMRinger: side chain–directed model and map validation for 3D cryo-electron microscopy
- (2015) Benjamin A Barad et al. NATURE METHODS
- 2.2 A resolution cryo-EM structure of -galactosidase in complex with a cell-permeant inhibitor
- (2015) A. Bartesaghi et al. SCIENCE
- Sampling the conformational space of the catalytic subunit of human γ-secretase
- (2015) Xiao-chen Bai et al. eLife
- A2aR antagonists: Next generation checkpoint blockade for cancer immunotherapy
- (2015) Robert D. Leone et al. Computational and Structural Biotechnology Journal
- Volta potential phase plate for in-focus phase contrast transmission electron microscopy
- (2014) R. Danev et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Adenosine A2A Receptor as a Drug Discovery Target
- (2013) Manuel de Lera Ruiz et al. JOURNAL OF MEDICINAL CHEMISTRY
- Molecular signatures of G-protein-coupled receptors
- (2013) A. J. Venkatakrishnan et al. NATURE
- Low-resolution refinement tools inREFMAC5
- (2012) Robert A. Nicholls et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Adenosine A2A Antagonists in Parkinson’s Disease: What’s Next?
- (2012) Patrick Hickey et al. Current Neurology and Neuroscience Reports
- Agonist-bound structures of G protein-coupled receptors
- (2012) Guillaume Lebon et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Discovery of 1,2,4-Triazine Derivatives as Adenosine A2A Antagonists using Structure Based Drug Design
- (2012) Miles Congreve et al. JOURNAL OF MEDICINAL CHEMISTRY
- RELION: Implementation of a Bayesian approach to cryo-EM structure determination
- (2012) Sjors H.W. Scheres JOURNAL OF STRUCTURAL BIOLOGY
- G-protein-coupled receptor inactivation by an allosteric inverse-agonist antibody
- (2012) Tomoya Hino et al. NATURE
- Structural Basis for Allosteric Regulation of GPCRs by Sodium Ions
- (2012) W. Liu et al. SCIENCE
- REFMAC5 for the refinement of macromolecular crystal structures
- (2011) Garib N. Murshudov et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation
- (2011) Guillaume Lebon et al. NATURE
- Crystal structure of the β2 adrenergic receptor–Gs protein complex
- (2011) Søren G. F. Rasmussen et al. NATURE
- International Union of Basic and Clinical Pharmacology. LXXXI. Nomenclature and Classification of Adenosine Receptors--An Update
- (2011) B. B. Fredholm et al. PHARMACOLOGICAL REVIEWS
- Structure of an Agonist-Bound Human A2A Adenosine Receptor
- (2011) F. Xu et al. SCIENCE
- Structure of the Adenosine A2A Receptor in Complex with ZM241385 and the Xanthines XAC and Caffeine
- (2011) Andrew S. Doré et al. STRUCTURE
- PHENIX: a comprehensive Python-based system for macromolecular structure solution
- (2010) Paul D. Adams et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- MolProbity: all-atom structure validation for macromolecular crystallography
- (2009) Vincent B. Chen et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Engineering G protein-coupled receptors to facilitate their structure determination
- (2009) Christopher G Tate et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- The 2.6 Angstrom Crystal Structure of a Human A2A Adenosine Receptor Bound to an Antagonist
- (2008) V.-P. Jaakola et al. SCIENCE
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now