Single particle electron cryomicroscopy: trends, issues and future perspective

Factors that Influence the Formation and Stability of Thin, Cryo-EM Specimens

(2016) Robert M. Glaeser et al.   BIOPHYSICAL JOURNAL

Ultrastable gold substrates: Properties of a support for high-resolution electron cryomicroscopy of biological specimens

(2016) Christopher J. Russo et al.   JOURNAL OF STRUCTURAL BIOLOGY

Overview and future of single particle electron cryomicroscopy

(2015) Richard Henderson   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Three-dimensional reconstruction of helical polymers

(2015) Edward H. Egelman   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Membrane protein structures without crystals, by single particle electron cryomicroscopy

(2015) Kutti R Vinothkumar   CURRENT OPINION IN STRUCTURAL BIOLOGY

FEI’s direct electron detector developments: Embarking on a revolution in cryo-TEM

(2015) Maarten Kuijper et al.   JOURNAL OF STRUCTURAL BIOLOGY

Alignment of cryo-EM movies of individual particles by optimization of image translations

(2015) John L. Rubinstein et al.   JOURNAL OF STRUCTURAL BIOLOGY

The structure of the human mitochondrial ribosome

(2015) A. Amunts et al.   SCIENCE

Thon rings from amorphous ice and implications of beam-induced Brownian motion in single particle electron cryo-microscopy

(2015) G. McMullan et al.   ULTRAMICROSCOPY

A national facility for biological cryo-electron microscopy

(2015) Helen R. Saibil et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Architecture of mammalian respiratory complex I

(2014) Kutti R. Vinothkumar et al.   NATURE

Controlling protein adsorption on graphene for cryo-EM using low-energy hydrogen plasmas

(2014) Christopher J Russo et al.   NATURE METHODS

Volta potential phase plate for in-focus phase contrast transmission electron microscopy

(2014) R. Danev et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ultrastable gold substrates for electron cryomicroscopy

(2014) C. J. Russo et al.   SCIENCE

Molecular Mechanism of Antibody-Mediated Activation of β-galactosidase

(2014) Kutti R. Vinothkumar et al.   STRUCTURE

Comparison of optimal performance at 300keV of three direct electron detectors for use in low dose electron microscopy

(2014) G. McMullan et al.   ULTRAMICROSCOPY

Self-assembled monolayers improve protein distribution on holey carbon cryo-EM supports

(2014) Joel R. Meyerson et al.   Scientific Reports

Influence of electron dose rate on electron counting images recorded with the K2 camera

(2013) Xueming Li et al.   JOURNAL OF STRUCTURAL BIOLOGY

Likelihood-based classification of cryo-EM images using FREALIGN

(2013) Dmitry Lyumkis et al.   JOURNAL OF STRUCTURAL BIOLOGY

Cryomicroscopy of radiation sensitive specimens on unmodified graphene sheets: Reduction of electron-optical effects of charging

(2013) Kasim Sader et al.   JOURNAL OF STRUCTURAL BIOLOGY

Structure of the TRPV1 ion channel determined by electron cryo-microscopy

(2013) Maofu Liao et al.   NATURE

Electron counting and beam-induced motion correction enable near-atomic-resolution single-particle cryo-EM

(2013) Xueming Li et al.   NATURE METHODS

Avoiding the pitfalls of single particle cryo-electron microscopy: Einstein from noise

(2013) R. Henderson   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PRIME: Probabilistic Initial 3D Model Generation for Single-Particle Cryo-Electron Microscopy

(2013) Hans Elmlund et al.   STRUCTURE

High-resolution noise substitution to measure overfitting and validate resolution in 3D structure determination by single particle electron cryomicroscopy

(2013) Shaoxia Chen et al.   ULTRAMICROSCOPY

Beam-induced motion of vitrified specimen on holey carbon film

(2012) Axel F. Brilot et al.   JOURNAL OF STRUCTURAL BIOLOGY

SIMPLE: Software for ab initio reconstruction of heterogeneous single-particles

(2012) Dominika Elmlund et al.   JOURNAL OF STRUCTURAL BIOLOGY

RELION: Implementation of a Bayesian approach to cryo-EM structure determination

(2012) Sjors H.W. Scheres   JOURNAL OF STRUCTURAL BIOLOGY

Prevention of overfitting in cryo-EM structure determination

(2012) Sjors H W Scheres et al.   NATURE METHODS

Movies of Ice-Embedded Particles Enhance Resolution in Electron Cryo-Microscopy

(2012) Melody G. Campbell et al.   STRUCTURE

Outcome of the First Electron Microscopy Validation Task Force Meeting

(2012) Richard Henderson et al.   STRUCTURE

Paraxial charge compensator for electron cryomicroscopy

(2012) John A. Berriman et al.   ULTRAMICROSCOPY

Near-atomic resolution reconstructions of icosahedral viruses from electron cryo-microscopy

(2011) Nikolaus Grigorieff et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Electron tomography of cells

(2011) Lu Gan et al.   QUARTERLY REVIEWS OF BIOPHYSICS

3.3 Å Cryo-EM Structure of a Nonenveloped Virus Reveals a Priming Mechanism for Cell Entry

(2010) Xing Zhang et al.   CELL

Ribosome dynamics and tRNA movement by time-resolved electron cryomicroscopy

(2010) Niels Fischer et al.   NATURE

Cryo-EM structure and rRNA model of a translating eukaryotic 80S ribosome at 5.5-A resolution

(2010) J.-P. Armache et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Atomic Structure of Human Adenovirus by Cryo-EM Reveals Interactions Among Protein Networks

(2010) H. Liu et al.   SCIENCE

Zernike Phase Contrast Cryo-Electron Microscopy and Tomography for Structure Determination at Nanometer and Subnanometer Resolutions

(2010) Kazuyoshi Murata et al.   STRUCTURE

Images of paraffin monolayer crystals with perfect contrast: Minimization of beam-induced specimen motion

(2010) R.M. Glaeser et al.   ULTRAMICROSCOPY

First application of Cc-corrected imaging for high-resolution and energy-filtered TEM

(2009) B. Kabius et al.   Microscopy

Graphene oxide: A substrate for optimizing preparations of frozen-hydrated samples

(2009) Radosav S. Pantelic et al.   JOURNAL OF STRUCTURAL BIOLOGY

Origin and temperature dependence of radiation damage in biological samples at cryogenic temperatures

(2009) A. Meents et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Experimental observation of the improvement in MTF from backthinning a CMOS direct electron detector

(2009) G. McMullan et al.   ULTRAMICROSCOPY

Detective quantum efficiency of electron area detectors in electron microscopy

(2009) G. McMullan et al.   ULTRAMICROSCOPY

Enhanced imaging in low dose electron microscopy using electron counting

(2009) G. McMullan et al.   ULTRAMICROSCOPY

Near-atomic resolution using electron cryomicroscopy and single-particle reconstruction

(2008) X. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA