Targeting posttranslational modifications of RIOK1 inhibits the progression of colorectal and gastric cancers

The Atypical Kinase RIOK1 Promotes Tumor Growth and Invasive Behavior

(2017) Florian Weinberg et al.   EBioMedicine

Toward selective CK2alpha and CK2alpha’ inhibitors: Development of a novel whole-cell kinase assay by Autodisplay of catalytic CK2alpha’

(2016) Andre Bollacke et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Methylation-dependent regulation of HIF-1α stability restricts retinal and tumour angiogenesis

(2016) Yunho Kim et al.   Nature Communications

Increased PTP1B expression and phosphatase activity in colorectal cancer results in a more invasive phenotype and worse patient outcome

(2016) Elmer Hoekstra et al.   Oncotarget

Set7 mediated Gli3 methylation plays a positive role in the activation of Sonic Hedgehog pathway in mammals

(2016) Lin Fu et al.   eLife

Modulation of LSD1 phosphorylation by CK2/WIP1 regulates RNF168-dependent 53BP1 recruitment in response to DNA damage

(2015) Bin Peng et al.   NUCLEIC ACIDS RESEARCH

Investigating the Role of RIO Protein Kinases in Caenorhabditis elegans

(2015) Tasha K. Mendes et al.   PLoS One

Rio1 promotes rDNA stability and downregulates RNA polymerase I to ensure rDNA segregation

(2015) Maria G. Iacovella et al.   Nature Communications

Reduced expression of SET7/9, a histone mono-methyltransferase, is associated with gastric cancer progression

(2015) Yoshimitsu Akiyama et al.   Oncotarget

Quinone Reductase 2 Is an Adventitious Target of Protein Kinase CK2 Inhibitors TBBz (TBI) and DMAT

(2014) Kevin K. K. Leung et al.   BIOCHEMISTRY

Expression pattern and first functional characterization of riok-1 in Caenorhabditis elegans

(2014) Florian Weinberg et al.   GENE EXPRESSION PATTERNS

A Methylation-Phosphorylation Switch Determines Sox2 Stability and Function in ESC Maintenance or Differentiation

(2014) Lan Fang et al.   MOLECULAR CELL

Exploring features and function of Ss-riok-3, an enigmatic kinase gene from Strongyloides stercoralis

(2014) Wang Yuan et al.   Parasites & Vectors

Phosphorylation-dependent regulation of plant chromatin and chromatin-associated proteins

(2014) Jean Bigeard et al.   PROTEOMICS

Early colon cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

(2013) R. Labianca et al.   ANNALS OF ONCOLOGY

Factors Associated With Risk for Colorectal Cancer Recurrence After Endoscopic Resection of T1 Tumors

(2013) Shinji Yoshii et al.   Clinical Gastroenterology and Hepatology

Control of the Hippo Pathway by Set7-Dependent Methylation of Yap

(2013) Menno J. Oudhoff et al.   DEVELOPMENTAL CELL

An integrated systems genetics screen reveals the transcriptional structure of inherited predisposition to metastatic disease

(2013) F. Faraji et al.   GENOME RESEARCH

PTEN antagonises Tcl1/hnRNPK-mediated G6PD pre-mRNA splicing which contributes to hepatocarcinogenesis

(2013) Xuehui Hong et al.   GUT

Methylation of SUV39H1 by SET7/9 results in heterochromatin relaxation and genome instability

(2013) D. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Kinome-Wide RNAi Screen in Drosophila Glia Reveals That the RIO Kinases Mediate Cell Proliferation and Survival through TORC2-Akt Signaling in Glioblastoma

(2013) Renee D. Read et al.   PLoS Genetics

Loss of LSD1 (lysine-specific demethylase 1) suppresses growth and alters gene expression of human colon cancer cells in a p53- and DNMT1(DNA methyltransferase 1)-independent manner

(2012) Lihua Jin et al.   BIOCHEMICAL JOURNAL

The importance of post-translational modifications in regulating Saccharomyces cerevisiae metabolism

(2011) Ana Paula Oliveira et al.   FEMS YEAST RESEARCH

The kinase activity of human Rio1 is required for final steps of cytoplasmic maturation of 40S subunits

(2011) Barbara Widmann et al.   MOLECULAR BIOLOGY OF THE CELL

The biology of lysine acetylation integrates transcriptional programming and metabolism

(2011) Jigneshkumar Patel et al.   Nutrition & Metabolism

Overexpression of Nuclear Protein Kinase CK2 α Catalytic Subunit (CK2α) as a Poor Prognosticator in Human Colorectal Cancer

(2011) Kai-Yuan Lin et al.   PLoS One

LSD1 demethylates histone and non-histone proteins

(2010) Thomas B. Nicholson et al.   Epigenetics

RioK1, a New Interactor of Protein Arginine Methyltransferase 5 (PRMT5), Competes with pICln for Binding and Modulates PRMT5 Complex Composition and Substrate Specificity

(2010) Gernot Guderian et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A methylation and phosphorylation switch between an adjacent lysine and serine determines human DNMT1 stability

(2010) Pierre-Olivier Estève et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A Global Protein Kinase and Phosphatase Interaction Network in Yeast

(2010) A. Breitkreutz et al.   SCIENCE

A Genome-wide RNAi Screen Identifies Multiple Synthetic Lethal Interactions with the Ras Oncogene

(2009) Ji Luo et al.   CELL

The F Box Protein Fbx6 Regulates Chk1 Stability and Cellular Sensitivity to Replication Stress

(2009) You-Wei Zhang et al.   MOLECULAR CELL

Role of the Histone H3 Lysine 4 Methyltransferase, SET7/9, in the Regulation of NF-κB-dependent Inflammatory Genes

(2008) Yan Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY