Crk proteins transduce FGF signaling to promote lens fiber cell elongation

The molecular mechanisms underlying lens fiber elongation

(2017) Dylan S. Audette et al.   EXPERIMENTAL EYE RESEARCH

Signaling and Gene Regulatory Networks in Mammalian Lens Development

(2017) Ales Cvekl et al.   TRENDS IN GENETICS

β1‐integrin controls cell fate specification in early lens development

(2016) Mallika Pathania et al.   DIFFERENTIATION

Prox1 and fibroblast growth factor receptors form a novel regulatory loop controlling lens fiber differentiation and gene expression

(2015) Dylan S. Audette et al.   DEVELOPMENT

Rap1 GTPase is required for mouse lens epithelial maintenance and morphogenesis

(2015) Rupalatha Maddala et al.   DEVELOPMENTAL BIOLOGY

Fgfr1 regulates development through the combinatorial use of signaling proteins

(2015) J. Richard Brewer et al.   GENES & DEVELOPMENT

CRK proteins selectively regulate T cell migration into inflamed tissues

(2015) Yanping Huang et al.   JOURNAL OF CLINICAL INVESTIGATION

Sorbs1 and 2 interact with Crk-L and are required for Acetylcholine receptor cluster formation

(2015) Peter T. Hallock et al.   MOLECULAR AND CELLULAR BIOLOGY

Matrix Metalloproteinase-9–Null Mice Are Resistant to TGF-β–Induced Anterior Subcapsular Cataract Formation

(2014) Anna Korol et al.   AMERICAN JOURNAL OF PATHOLOGY

Crk1/2 and CrkL form a hetero-oligomer and functionally complement each other during podocyte morphogenesis

(2014) Britta George et al.   KIDNEY INTERNATIONAL

MAPK1 is required for establishing the pattern of cell proliferation and for cell survival during lens development

(2013) D. Upadhya et al.   DEVELOPMENT

Frs2  and Shp2 signal independently of Gab to mediate FGF signaling in lens development

(2013) H. Li et al.   JOURNAL OF CELL SCIENCE

Frs2  enhances fibroblast growth factor-mediated survival and differentiation in lens development

(2012) B. P. Madakashira et al.   DEVELOPMENT

The functional role of the Meis/Prep-binding elements in Pax6 locus during pancreas and eye development

(2012) Christian Carbe et al.   DEVELOPMENTAL BIOLOGY

Generation of Fgfr3 Conditional Knockout Mice

(2012) Nan Su et al.   International Journal of Biological Sciences

Reelin Controls Neuronal Positioning by Promoting Cell-Matrix Adhesion via Inside-Out Activation of Integrin α5β1

(2012) Katsutoshi Sekine et al.   NEURON

Life at the Leading Edge

(2011) Anne J. Ridley   CELL

Rac1 GTPase-deficient mouse lens exhibits defects in shape, suture formation, fiber cell migration and survival

(2011) Rupalatha Maddala et al.   DEVELOPMENTAL BIOLOGY

The function of FGF signaling in the lens placode

(2011) Claudia M. Garcia et al.   DEVELOPMENTAL BIOLOGY

Grb2 regulates B-cell maturation, B-cell memory responses and inhibits B-cell Ca2+signalling

(2011) Jochen A Ackermann et al.   EMBO JOURNAL

Lens induction requires attenuation of ERK signaling by Nf1

(2011) C. Carbe et al.   HUMAN MOLECULAR GENETICS

Loss of Shp2-Mediated Mitogen-Activated Protein Kinase Signaling in Muller Glial Cells Results in Retinal Degeneration

(2011) Z. Cai et al.   MOLECULAR AND CELLULAR BIOLOGY

The lens: a classical model of embryonic induction providing new insights into cell determination in early development

(2011) L. Gunhaga   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Balanced Rac1 and RhoA activities regulate cell shape and drive invagination morphogenesis in epithelia

(2011) B. K. Chauhan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulating Rap small G-proteins in time and space

(2011) Martijn Gloerich et al.   TRENDS IN CELL BIOLOGY

Sprouty2-modulated Kras signaling rescues Shp2 deficiency during lens and lacrimal gland development

(2010) Y. Pan et al.   DEVELOPMENT

Dok-7 regulates neuromuscular synapse formation by recruiting Crk and Crk-L

(2010) P. T. Hallock et al.   GENES & DEVELOPMENT

PI3 Kinase Signals BCR-Dependent Mature B Cell Survival

(2009) Lakshmi Srinivasan et al.   CELL

Crk and CrkL adaptor proteins: networks for physiological and pathological signaling

(2009) Raymond B Birge et al.   Cell Communication and Signaling

Co-operative roles for E-cadherin and N-cadherin during lens vesicle separation and lens epithelial cell survival

(2009) Giuseppe F. Pontoriero et al.   DEVELOPMENTAL BIOLOGY

Distinct roles for Crk adaptor isoforms in actin reorganization induced by extracellular signals

(2009) S. Antoku et al.   JOURNAL OF CELL SCIENCE

Structural and Functional Basis of a Role for CRKL in a Fibroblast Growth Factor 8-Induced Feed-Forward Loop

(2009) J.-H. Seo et al.   MOLECULAR AND CELLULAR BIOLOGY

Fibroblast growth factor receptor signaling is essential for lens fiber cell differentiation

(2008) Haotian Zhao et al.   DEVELOPMENTAL BIOLOGY

Enhanced Cortico-Amygdala Efficacy and Suppressed Fear in Absence of Rap1

(2008) B.-X. Pan et al.   JOURNAL OF NEUROSCIENCE

Crk and Crk-Like Play Essential Overlapping Roles Downstream of Disabled-1 in the Reelin Pathway

(2008) T.-J. Park et al.   JOURNAL OF NEUROSCIENCE

Rap1a Is a Key Regulator of Fibroblast Growth Factor 2-Induced Angiogenesis and Together with Rap1b Controls Human Endothelial Cell Functions

(2008) J. Yan et al.   MOLECULAR AND CELLULAR BIOLOGY

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(2008) Jeffrey Settleman et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY