Altered DNA methylation is associated with aberrant gene expression in parenchymal but not airway fibroblasts isolated from individuals with COPD

DNA methylation profiling in peripheral lung tissues of smokers and patients with COPD

(2017) Isaac K. Sundar et al.   Clinical Epigenetics

Human bronchial and parenchymal fibroblasts display differences in basal inflammatory phenotype and response to IL-17A

(2016) K. Dessalle et al.   CLINICAL AND EXPERIMENTAL ALLERGY

DNA methylation profiling in human lung tissue identifies genes associated with COPD

(2016) Jarrett D. Morrow et al.   Epigenetics

Increased DNA methylation variability in type 1 diabetes across three immune effector cell types

(2016) Dirk S. Paul et al.   Nature Communications

DNA methylation outliers in normal breast tissue identify field defects that are enriched in cancer

(2016) Andrew E Teschendorff et al.   Nature Communications

funtooNorm: an R package for normalization of DNA methylation data when there are multiple cell or tissue types

(2015) Kathleen Oros Klein et al.   BIOINFORMATICS

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

Integrative Analysis of DNA Methylation and Gene Expression Data Identifies EPAS1 as a Key Regulator of COPD

(2015) Seungyeul Yoo et al.   PLoS Genetics

Minfi: a flexible and comprehensive Bioconductor package for the analysis of Infinium DNA methylation microarrays

(2014) Martin J. Aryee et al.   BIOINFORMATICS

Differential effects of fluticasone on extracellular matrix production by airway and parenchymal fibroblasts in severe COPD

(2013) Corry-Anke Brandsma et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

DNA Methylation Is Globally Disrupted and Associated with Expression Changes in Chronic Obstructive Pulmonary Disease Small Airways

(2013) Emily A. Vucic et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Additional annotation enhances potential for biologically-relevant analysis of the Illumina Infinium HumanMethylation450 BeadChip array

(2013) Magda E Price et al.   Epigenetics & Chromatin

Variable DNA Methylation Is Associated with Chronic Obstructive Pulmonary Disease and Lung Function

(2011) Weiliang Qiu et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The role of IREB2 and transforming growth factor beta-1 genetic variants in COPD: a replication case-control study

(2011) Sally L Chappell et al.   BMC Medical Genetics

Pro-inflammatory phenotype of COPD fibroblasts not compatible with repair in COPD lung

(2011) Jing Zhang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Individual and Cumulative Effects of GWAS Susceptibility Loci in Lung Cancer: Associations after Sub-Phenotyping for COPD

(2011) Robert P. Young et al.   PLoS One

Wood Smoke Exposure and Gene Promoter Methylation Are Associated with Increased Risk for COPD in Smokers

(2010) Akshay Sood et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Human Lung Parenchyma but Not Proximal Bronchi Produces Fibroblasts with Enhanced TGF-β Signaling and α-SMA Expression

(2010) Dmitri V. Pechkovsky et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Comparison of Beta-value and M-value methods for quantifying methylation levels by microarray analysis

(2010) Pan Du et al.   BMC BIOINFORMATICS

Chromosome 4q31 locus in COPD is also associated with lung cancer

(2010) R. P. Young et al.   EUROPEAN RESPIRATORY JOURNAL

Genome-wide Association Study of Smoking Initiation and Current Smoking

(2009) Jacqueline M. Vink et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The 15q24/25 Susceptibility Variant for Lung Cancer and Chronic Obstructive Pulmonary Disease Is Associated with Emphysema

(2009) Diether Lambrechts et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Hedgehog-interacting protein is a COPD susceptibility gene: the Rotterdam Study

(2009) Y. M. T. A. Van Durme et al.   EUROPEAN RESPIRATORY JOURNAL

Genome-wide association study identifies five loci associated with lung function

(2009) Emmanouela Repapi et al.   NATURE GENETICS

Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function

(2009) Dana B Hancock et al.   NATURE GENETICS

Lung Fibroblast Repair Functions in Patients with Chronic Obstructive Pulmonary Disease Are Altered by Multiple Mechanisms

(2008) Shinsaku Togo et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Lung cancer gene associated with COPD: triple whammy or possible confounding effect?

(2008) R. P. Young et al.   EUROPEAN RESPIRATORY JOURNAL