Glucagon-Like Peptide-1 Mediates the Protective Effect of the Dipeptidyl Peptidase IV Inhibitor on Renal Fibrosis via Reducing the Phenotypic Conversion of Renal Microvascular Cells in Monocrotaline-Treated Rats

Role of the Renal Microcirculation in Progression of Chronic Kidney Injury in Obesity

(2016) Alejandro R. Chade et al.   AMERICAN JOURNAL OF NEPHROLOGY

Renoprotective effect of DPP-4 inhibitors against free fatty acid-bound albumin-induced renal proximal tubular cell injury

(2016) Yuki Tanaka et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Evaluation and Treatment of Endoplasmic Reticulum (ER) Stress in Right Ventricular Dysfunction during Monocrotaline-Induced Rat Pulmonary Arterial Hypertension

(2016) Jing-Jing Wang et al.   CARDIOVASCULAR DRUGS AND THERAPY

DA-1229, a dipeptidyl peptidase IV inhibitor, protects against renal injury by preventing podocyte damage in an animal model of progressive renal injury

(2016) Jee Eun Lee et al.   LABORATORY INVESTIGATION

Microcirculation in Acute and Chronic Kidney Diseases

(2015) Lara Zafrani et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Molecular Pathways Regulating Macrovascular Pathology and Vascular Smooth Muscle Cells Phenotype in Type 2 Diabetes

(2015) Sara Casella et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Chemical Profiles and Protective Effect of Hedyotis diffusa Willd in Lipopolysaccharide-Induced Renal Inflammation Mice

(2015) Jian-Hong Ye et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Endothelial-to-mesenchymal transition drives atherosclerosis progression

(2015) Pei-Yu Chen et al.   JOURNAL OF CLINICAL INVESTIGATION

Matrix Metalloproteinase 2 as a Potential Mediator of Vascular Smooth Muscle Cell Migration and Chronic Vascular Remodeling in Hypertension

(2015) V.A. Belo et al.   JOURNAL OF VASCULAR RESEARCH

Interactions of DPP-4 and integrin β1 influences endothelial-to-mesenchymal transition

(2015) Sen Shi et al.   KIDNEY INTERNATIONAL

Inhibition of dipeptidyl peptidase IV protects tacrolimus-induced kidney injury

(2015) Sun W Lim et al.   LABORATORY INVESTIGATION

Dipeptidyl peptidase-4 deficiency protects against experimental diabetic nephropathy partly by blocking the advanced glycation end products-receptor axis

(2015) Takanori Matsui et al.   LABORATORY INVESTIGATION

Effects of a DPP4 inhibitor on cisplatin-induced acute kidney injury: study protocol for a randomized controlled trial

(2015) Seon Ha Baek et al.   Trials

Cardiovascular Actions of Incretin-Based Therapies

(2014) John R. Ussher et al.   CIRCULATION RESEARCH

Integrin-linked kinase plays a key role in the regulation of angiotensin II-induced renal inflammation

(2014) Matilde Alique et al.   CLINICAL SCIENCE

Linagliptin-Mediated DPP-4 Inhibition Ameliorates Kidney Fibrosis in Streptozotocin-Induced Diabetic Mice by Inhibiting Endothelial-to-Mesenchymal Transition in a Therapeutic Regimen

(2014) Keizo Kanasaki et al.   DIABETES

Prevention of Obesity-Induced Renal Injury in Male Mice by DPP4 Inhibition

(2014) Ravi Nistala et al.   ENDOCRINOLOGY

Inhibition of Nuclear Factor-κB in the Lungs Prevents Monocrotaline-Induced Pulmonary Hypertension in Mice

(2014) Li Li et al.   HYPERTENSION

Thalidomide Ameliorates Cisplatin-Induced Nephrotoxicity by Inhibiting Renal Inflammation in an Experimental Model

(2014) Keyvan Amirshahrokhi et al.   INFLAMMATION

Cellular and molecular mechanisms in kidney fibrosis

(2014) Jeremy S. Duffield   JOURNAL OF CLINICAL INVESTIGATION

The potential for renoprotection with incretin-based drugs

(2014) Tetsuhiro Tanaka et al.   KIDNEY INTERNATIONAL

Dipeptidyl peptidase IV inhibitor protects against renal interstitial fibrosis in a mouse model of ureteral obstruction

(2014) Hye Sook Min et al.   LABORATORY INVESTIGATION

TGF-  Signaling Mediates Endothelial-to-Mesenchymal Transition (EndMT) During Vein Graft Remodeling

(2014) B. C. Cooley et al.   Science Translational Medicine

Hepatic cytochrome P450s play a major role in monocrotaline-induced renal toxicity in mice

(2013) Jun Yao et al.   ACTA PHARMACOLOGICA SINICA

Recent advances in understanding GLP-1R (glucagon-like peptide-1 receptor) function

(2013) Cassandra Koole et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Role of the endothelial-to-mesenchymal transition in renal fibrosis of chronic kidney disease

(2013) Jianhua He et al.   Clinical and Experimental Nephrology

The purinergic 2X7receptor participates in renal inflammation and injury induced by high-fat diet: possible role of NLRP3 inflammasome activation

(2013) Anna Solini et al.   JOURNAL OF PATHOLOGY

Protection of Glucagon-Like Peptide-1 in Cisplatin-Induced Renal Injury Elucidates Gut-Kidney Connection

(2013) D. Katagiri et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Origin and function of myofibroblasts in kidney fibrosis

(2013) Valerie S LeBleu et al.   NATURE MEDICINE

The gut–renal axis: do incretin-based agents confer renoprotection in diabetes?

(2013) Marcel H. A. Muskiet et al.   Nature Reviews Nephrology

Diabetic nephropathy: the role of inflammation in fibroblast activation and kidney fibrosis

(2013) Keizo Kanasaki et al.   Frontiers in Endocrinology

Vascular smooth muscle cell phenotypic plasticity: focus on chromatin remodelling

(2012) J. M. Spin et al.   CARDIOVASCULAR RESEARCH

Specific actions of GLP-1 receptor agonists and DPP4 inhibitors for the treatment of pancreatic β-cell impairments in type 2 diabetes

(2012) Stéphane Dalle et al.   CELLULAR SIGNALLING

Restoring the renal microvasculature to treat chronic kidney disease

(2012) David A. Long et al.   Nature Reviews Nephrology

Exendin-4 improved rat cortical neuron survival under oxygen/glucose deprivation through PKA pathway

(2012) M.-D. Wang et al.   NEUROSCIENCE

Functional phenotype of airway myocytes from asthmatic airways

(2012) David B. Wright et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Phenotype modulation of airway smooth muscle in asthma

(2012) David B. Wright et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Elastin Degradation and Vascular Smooth Muscle Cell Phenotype Change Precede Cell Loss and Arterial Medial Calcification in a Uremic Mouse Model of Chronic Kidney Disease

(2011) Ashwini Pai et al.   AMERICAN JOURNAL OF PATHOLOGY

Role of Endothelial-Mesenchymal Transition (EndoMT) in the Pathogenesis of Fibrotic Disorders

(2011) Sonsoles Piera-Velazquez et al.   AMERICAN JOURNAL OF PATHOLOGY

Deletion of soluble epoxide hydrolase gene improves renal endothelial function and reduces renal inflammation and injury in streptozotocin-induced type 1 diabetes

(2011) Ahmed A. Elmarakby et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Silencing of tissue factor by antisense deoxyoligonucleotide prevents monocrotaline/LPS renal injury in mice

(2011) Mohamed Sadek Abdel-Bakky et al.   ARCHIVES OF TOXICOLOGY

Micromanaging Vascular Smooth Muscle Cell Differentiation and Phenotypic Modulation

(2011) Brandi N. Davis-Dusenbery et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Targeted gene delivery of BMPR2 attenuates pulmonary hypertension

(2011) A. M. Reynolds et al.   EUROPEAN RESPIRATORY JOURNAL

The origin of interstitial myofibroblasts in chronic kidney disease

(2011) Ivica Grgic et al.   PEDIATRIC NEPHROLOGY

GLP-1 Analogs Reduce Hepatocyte Steatosis and Improve Survival by Enhancing the Unfolded Protein Response and Promoting Macroautophagy

(2011) Shvetank Sharma et al.   PLoS One

Mechanisms of Tubulointerstitial Fibrosis

(2010) M. Zeisberg et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Renal fibrosis: novel insights into mechanisms and therapeutic targets

(2010) Peter Boor et al.   Nature Reviews Nephrology

Prediction, Progression, and Outcomes of Chronic Kidney Disease in Older Adults

(2009) S. Anderson et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The role of endothelial-to-mesenchymal transition in cancer progression

(2008) S Potenta et al.   BRITISH JOURNAL OF CANCER

Fibroblasts emerge via epithelial-mesenchymal transition in chronic kidney fibrosis

(2008) Michael Zeisberg   Frontiers in Bioscience-Landmark

Fibroblasts in Kidney Fibrosis Emerge via Endothelial-to-Mesenchymal Transition

(2008) E. M. Zeisberg et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY