RavN is a member of a previously unrecognized group of Legionella pneumophila E3 ubiquitin ligases

Phosphoribosylation of Ubiquitin Promotes Serine Ubiquitination and Impairs Conventional Ubiquitination

(2016) Sagar Bhogaraju et al.   CELL

Ubiquitination independent of E1 and E2 enzymes by bacterial effectors

(2016) Jiazhang Qiu et al.   NATURE

Genomic analysis of 38 Legionella species identifies large and diverse effector repertoires

(2016) David Burstein et al.   NATURE GENETICS

Host Cell-catalyzedS-Palmitoylation Mediates Golgi Targeting of theLegionellaUbiquitin Ligase GobX

(2015) Yi-Han Lin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Secondary ubiquitin-RING docking enhances Arkadia and Ark2C E3 ligase activity

(2015) Joshua D Wright et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Molecular Characterization of LubX: Functional Divergence of the U-Box Fold by Legionella pneumophila

(2015) Andrew T. Quaile et al.   STRUCTURE

Secondary ubiquitin-RING docking enhances Arkadia and Ark2C E3 ligase activity

(2015) Joshua D Wright et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure of the Legionella Virulence Factor, SidC Reveals a Unique PI(4)P-Specific Binding Domain Essential for Its Targeting to the Bacterial Phagosome

(2015) Xi Luo et al.   PLoS Pathogens

Allosteric activation of the RNF146 ubiquitin ligase by a poly(ADP-ribosyl)ation signal

(2014) Paul A. DaRosa et al.   NATURE

The Legionella effector SidC defines a unique family of ubiquitin ligases important for bacterial phagosomal remodeling

(2014) F. Hsu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Developments in optics and performance at BL13-XALOC, the macromolecular crystallography beamline at the Alba Synchrotron

(2014) Jordi Juanhuix et al.   JOURNAL OF SYNCHROTRON RADIATION

Versatile Roles of K63-Linked Ubiquitin Chains in Trafficking

(2014) Zoi Erpapazoglou et al.   Cells

Visual automated macromolecular model building

(2013) Gerrit G. Langer et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

The Ubiquitin Code

(2012) David Komander et al.   Annual Review of Biochemistry

Development of proteasome inhibitors as research tools and cancer drugs

(2012) Alfred L. Goldberg   JOURNAL OF CELL BIOLOGY

HECT and RING finger families of E3 ubiquitin ligases at a glance

(2012) M. B. Metzger et al.   JOURNAL OF CELL SCIENCE

Aggravating Genetic Interactions Allow a Solution to Redundancy in a Bacterial Pathogen

(2012) T. J. O'Connor et al.   SCIENCE

Diverse ubiquitin signaling in NF-κB activation

(2012) Kazuhiro Iwai   TRENDS IN CELL BIOLOGY

Functional Analysis of NopM, a Novel E3 Ubiquitin Ligase (NEL) Domain Effector of Rhizobium sp. Strain NGR234

(2012) Da-Wei Xin et al.   PLoS Pathogens

Conserved Structural Mechanisms for Autoinhibition in IpaH Ubiquitin Ligases

(2011) Yang-Chieh Chou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Comprehensive Identification of Protein Substrates of the Dot/Icm Type IV Transporter of Legionella pneumophila

(2011) Wenhan Zhu et al.   PLoS One

RINGs hold the key to ubiquitin transfer

(2011) Rhesa Budhidarmo et al.   TRENDS IN BIOCHEMICAL SCIENCES

Experimental phasing withSHELXC/D/E: combining chain tracing with density modification

(2010) George M. Sheldrick   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Integration, scaling, space-group assignment and post-refinement

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Modulation of Host Cell Function byLegionella pneumophilaType IV Effectors

(2010) Andree Hubber et al.   Annual Review of Cell and Developmental Biology

The Legionella pneumophila F-box protein Lpp2082 (AnkB) modulates ubiquitination of the host protein parvin B and promotes intracellular replication

(2010) M. Lomma et al.   CELLULAR MICROBIOLOGY

The E Block motif is associated with Legionella pneumophila translocated substrates

(2010) Li Huang et al.   CELLULAR MICROBIOLOGY

E3 Ubiquitin Ligase Activity and Targeting of BAT3 by Multiple Legionella pneumophila Translocated Substrates

(2010) A. W. Ensminger et al.   INFECTION AND IMMUNITY

Biochemical and Structural Studies of a HECT-like Ubiquitin Ligase fromEscherichia coliO157:H7

(2010) David Yin-wei Lin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NleG Type 3 Effectors from Enterohaemorrhagic Escherichia coli Are U-Box E3 Ubiquitin Ligases

(2010) Bin Wu et al.   PLoS Pathogens

Legionella Metaeffector Exploits Host Proteasome to Temporally Regulate Cognate Effector

(2010) Tomoko Kubori et al.   PLoS Pathogens

Breaking the chains: structure and function of the deubiquitinases

(2009) David Komander et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A family of Salmonella virulence factors functions as a distinct class of autoregulated E3 ubiquitin ligases

(2009) C. M. Quezada et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular Mimicry by an F-Box Effector of Legionella pneumophila Hijacks a Conserved Polyubiquitination Machinery within Macrophages and Protozoa

(2009) Christopher T. Price et al.   PLoS Pathogens

Searching protein structure databases with DaliLite v.3

(2008) L. Holm et al.   BIOINFORMATICS

TheLegionella pneumophilaphosphatidylinositol-4 phosphate-binding type IV substrate SidC recruits endoplasmic reticulum vesicles to a replication-permissive vacuole

(2008) Curdin Ragaz et al.   CELLULAR MICROBIOLOGY

Large-scale identification ofLegionella pneumophilaDot/Icm substrates that modulate host cell vesicle trafficking pathways

(2008) Matthew Heidtman et al.   CELLULAR MICROBIOLOGY

Identification of a Hypervariable Region Containing New Legionella pneumophila Icm/Dot Translocated Substrates by Using the Conserved icmQ Regulatory Signature

(2008) T. Zusman et al.   INFECTION AND IMMUNITY

Legionella translocates an E3 ubiquitin ligase that has multiple U-boxes with distinct functions

(2008) Tomoko Kubori et al.   MOLECULAR MICROBIOLOGY

Structure of the Shigella T3SS effector IpaH defines a new class of E3 ubiquitin ligases

(2008) Alexander U Singer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Interactions between the quality control ubiquitin ligase CHIP and ubiquitin conjugating enzymes

(2008) Zhen Xu et al.   BMC STRUCTURAL BIOLOGY

Legionella Eukaryotic-Like Type IV Substrates Interfere with Organelle Trafficking

(2008) Karim Suwwan de Felipe et al.   PLoS Pathogens