Structure of the Legionella Virulence Factor, SidC Reveals a Unique PI(4)P-Specific Binding Domain Essential for Its Targeting to the Bacterial Phagosome

Bacterial Pathogen Manipulation of Host Membrane Trafficking

(2014) Seblewongel Asrat et al.   Annual Review of Cell and Developmental Biology

A novel probe for phosphatidylinositol 4-phosphate reveals multiple pools beyond the Golgi

(2014) Gerald R.V. Hammond et al.   JOURNAL OF CELL BIOLOGY

The Legionella effector SidC defines a unique family of ubiquitin ligases important for bacterial phagosomal remodeling

(2014) F. Hsu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Basis for PI(4)P-Specific Membrane Recruitment of the Legionella pneumophila Effector DrrA/SidM

(2014) Claudia M. Del Campo et al.   STRUCTURE

Legionella pneumophilaSubversion of Host Vesicular Transport by SidC Effector Proteins

(2014) Florian A. Horenkamp et al.   TRAFFIC

Live-Cell Imaging of Phosphoinositide Dynamics and Membrane Architecture during Legionella Infection

(2014) S. Weber et al.   mBio

The Machinery at Endoplasmic Reticulum-Plasma Membrane Contact Sites Contributes to Spatial Regulation of Multiple Legionella Effector Proteins

(2014) Andree Hubber et al.   PLoS Pathogens

A Rab-Centric Perspective of Bacterial Pathogen-Occupied Vacuoles

(2013) Racquel Kim Sherwood et al.   Cell Host & Microbe

Identification and Structural Characterization of aLegionellaPhosphoinositide Phosphatase

(2013) Leila Toulabi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal structures of two bacterial HECT-like E3 ligases in complex with a human E2 reveal atomic details of pathogen-host interactions

(2012) D. Y.-w. Lin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis for substrate recognition by a unique Legionella phosphoinositide phosphatase

(2012) F. Hsu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular Basis of Phosphatidylinositol 4-Phosphate and ARF1 GTPase Recognition by the FAPP1 Pleckstrin Homology (PH) Domain

(2011) Ju He et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Legionella pneumophila SidD is a deAMPylase that modifies Rab1

(2011) Yunhao Tan et al.   NATURE

Modulation of Rab GTPase function by a protein phosphocholine transferase

(2011) Shaeri Mukherjee et al.   NATURE

Comprehensive Identification of Protein Substrates of the Dot/Icm Type IV Transporter of Legionella pneumophila

(2011) Wenhan Zhu et al.   PLoS One

Legionella pneumophila regulates the small GTPase Rab1 activity by reversible phosphorylcholination

(2011) Y. Tan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

De-AMPylation of the Small GTPase Rab1 by the Pathogen Legionella pneumophila

(2011) M. R. Neunuebel et al.   SCIENCE

Conditional Peripheral Membrane Proteins: Facing up to Limited Specificity

(2011) Katarina Moravcevic et al.   STRUCTURE

High-affinity binding of phosphatidylinositol 4-phosphate by Legionella pneumophila DrrA

(2010) Stefan Schoebel et al.   EMBO REPORTS

Structural mechanism of host Rab1 activation by the bifunctional Legionella type IV effector SidM/DrrA

(2010) Y. Zhu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Legionella Effector Protein DrrA AMPylates the Membrane Traffic Regulator Rab1b

(2010) M. P. Muller et al.   SCIENCE

Coordination of Golgi functions by phosphatidylinositol 4-kinases

(2010) Todd R. Graham et al.   TRENDS IN CELL BIOLOGY

Inhibition of Host Vacuolar H+-ATPase Activity by a Legionella pneumophila Effector

(2010) Li Xu et al.   PLoS Pathogens

Insights into Ubiquitin Transfer Cascades from a Structure of a UbcH5B∼Ubiquitin-HECTNEDD4L Complex

(2009) Hari B. Kamadurai et al.   MOLECULAR CELL

Rab GTPases as coordinators of vesicle traffic

(2009) Harald Stenmark   NATURE REVIEWS MOLECULAR CELL BIOLOGY

TheLegionella pneumophilaphosphatidylinositol-4 phosphate-binding type IV substrate SidC recruits endoplasmic reticulum vesicles to a replication-permissive vacuole

(2008) Curdin Ragaz et al.   CELLULAR MICROBIOLOGY

The inositol polyphosphate 5-phosphatase OCRL1 restricts intracellular growth ofLegionella, localizes to the replicative vacuole and binds to the bacterial effector LpnE

(2008) Stefan S. Weber et al.   CELLULAR MICROBIOLOGY

Rab1 Guanine Nucleotide Exchange Factor SidM Is a Major Phosphatidylinositol 4-Phosphate-binding Effector Protein ofLegionella pneumophila

(2008) Eva Brombacher et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The multiple roles of PtdIns(4)P - not just the precursor of PtdIns(4,5)P2

(2008) G. D'Angelo et al.   JOURNAL OF CELL SCIENCE

The Legionella pneumophila replication vacuole: making a cosy niche inside host cells

(2008) Ralph R. Isberg et al.   NATURE REVIEWS MICROBIOLOGY

Structure of the Shigella T3SS effector IpaH defines a new class of E3 ubiquitin ligases

(2008) Alexander U Singer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY