SmSP2: A serine protease secreted by the blood fluke pathogen Schistosoma mansoni with anti-hemostatic properties

Serine proteases in schistosomes and other trematodes

(2018) Jan Dvorak et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Vesicle-based secretion in schistosomes: Analysis of protein and microRNA (miRNA) content of exosome-like vesicles derived from Schistosoma mansoni

(2018) Vitalie Samoil et al.   Scientific Reports

The human blood parasite Schistosoma mansoni expresses extracellular tegumental calpains that cleave the blood clotting protein fibronectin

(2017) Qiang Wang et al.   Scientific Reports

Excretion/secretion products from Schistosoma mansoni adults, eggs and schistosomula have unique peptidase specificity profiles

(2016) Jan Dvořák et al.   BIOCHIMIE

Digestive proteolysis in the Colorado potato beetle, Leptinotarsa decemlineata: Activity-based profiling and imaging of a multipeptidase network

(2016) Jaroslav Srp et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Extracellular vesicles secreted by Schistosoma mansoni contain protein vaccine candidates

(2016) Javier Sotillo et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Molecular characterization of S. japonicum exosome-like vesicles reveals their regulatory roles in parasite-host interactions

(2016) Lihui Zhu et al.   Scientific Reports

Schistosomiasis and its treatment

(2015) Conor R Caffrey   Future Medicinal Chemistry

Serine Proteases of Parasitic Helminths

(2015) Yong Yang et al.   KOREAN JOURNAL OF PARASITOLOGY

Prolyl Oligopeptidase from the Blood Fluke Schistosoma mansoni: From Functional Analysis to Anti-schistosomal Inhibitors

(2015) Pavla Fajtová et al.   PLoS Neglected Tropical Diseases

Schistosomes Enhance Plasminogen Activation: The Role of Tegumental Enolase

(2015) Barbara C. Figueiredo et al.   PLoS Pathogens

Of Monkeys and Men: Immunomic Profiling of Sera from Humans and Non-Human Primates Resistant to Schistosomiasis Reveals Novel Potential Vaccine Candidates

(2015) Mark S. Pearson et al.   Frontiers in Immunology

Activation Route of the Schistosoma mansoni Cathepsin B1 Drug Target: Structural Map with a Glycosaminoglycan Switch

(2014) Adéla Jílková et al.   STRUCTURE

Schistosomes versus platelets

(2014) Akram A. Da’dara et al.   THROMBOSIS RESEARCH

Trypsin- and Chymotrypsin-Like Serine Proteases in Schistosoma mansoni – ‘The Undiscovered Country’

(2014) Martin Horn et al.   PLoS Neglected Tropical Diseases

Quantum Mechanics-Based Scoring Rationalizes the Irreversible Inactivation of Parasitic Schistosoma mansoni Cysteine Peptidase by Vinyl Sulfone Inhibitors

(2013) Jindřich Fanfrlík et al.   JOURNAL OF PHYSICAL CHEMISTRY B

MEROPS: the database of proteolytic enzymes, their substrates and inhibitors

(2013) Neil D. Rawlings et al.   NUCLEIC ACIDS RESEARCH

Interference with the Host Haemostatic System by Schistosomes

(2013) Mirjam M. Mebius et al.   PLoS Pathogens

Characterization of Gut-associated Cathepsin D Hemoglobinase from TickIxodes ricinus(IrCD1)

(2012) Daniel Sojka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Global identification of peptidase specificity by multiplex substrate profiling

(2012) Anthony J O'Donoghue et al.   NATURE METHODS

Investigation of the Proteolytic Functions of an Expanded Cercarial Elastase Gene Family in Schistosoma mansoni

(2012) Jessica R. Ingram et al.   PLoS Neglected Tropical Diseases

Mapping the Pro-Peptide of theSchistosoma mansoniCathepsin B1 Drug Target: Modulation of Inhibition by Heparin and Design of Mimetic Inhibitors

(2011) Martin Horn et al.   ACS Chemical Biology

New topics in bradykinin research

(2011) M. Maurer et al.   ALLERGY

Manipulation of vascular function by blood flukes?

(2011) Akram Da'dara et al.   BLOOD REVIEWS

Structural Basis for Inhibition of Cathepsin B Drug Target from the Human Blood Fluke,Schistosoma mansoni

(2011) Adéla Jílková et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TsAg5, a Taenia solium cysticercus protein with a marginal trypsin-like activity in the diagnosis of human neurocysticercosis

(2011) Analiz Rueda et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

SignalP 4.0: discriminating signal peptides from transmembrane regions

(2011) Thomas Nordahl Petersen et al.   NATURE METHODS

Gene cloning, expression, and localization of antigen 5 in the life cycle of Echinococcus granulosus

(2011) Yuzhe Li et al.   PARASITOLOGY RESEARCH

Rapid induction of IgE responses to a worm cysteine protease during murine pre-patent schistosome infection

(2010) Lucia A de Oliveira Fraga et al.   BMC IMMUNOLOGY

RNA Interference in Schistosoma mansoni Schistosomula: Selectivity, Sensitivity and Operation for Larger-Scale Screening

(2010) Saša Štefanić et al.   PLoS Neglected Tropical Diseases

Parasites and poverty: The case of schistosomiasis

(2009) Charles H. King   ACTA TROPICA

Elucidating the transcriptome of Fasciola hepatica — A key to fundamental and biotechnological discoveries for a neglected parasite

(2009) Neil D. Young et al.   BIOTECHNOLOGY ADVANCES

Hemoglobin Digestion in Blood-Feeding Ticks: Mapping a Multipeptidase Pathway by Functional Proteomics

(2009) Martin Horn et al.   CHEMISTRY & BIOLOGY

MASP-1, a Promiscuous Complement Protease: Structure of Its Catalytic Region Reveals the Basis of Its Broad Specificity

(2009) J. Dobo et al.   JOURNAL OF IMMUNOLOGY

The genome of the blood fluke Schistosoma mansoni

(2009) Matthew Berriman et al.   NATURE

Improved visualization of protein consensus sequences by iceLogo

(2009) Niklaas Colaert et al.   NATURE METHODS

Immunopathogenesis of human schistosomiasis

(2009) M. L. BURKE et al.   PARASITE IMMUNOLOGY

SmCL3, a Gastrodermal Cysteine Protease of the Human Blood Fluke Schistosoma mansoni

(2009) Jan Dvořák et al.   PLoS Neglected Tropical Diseases

Differential use of protease families for invasion by schistosome cercariae

(2007) Jan Dvořák et al.   BIOCHIMIE