Lipidated apolipoprotein E4 structure and its receptor binding mechanism determined by a combined cross-linking coupled to mass spectrometry and molecular dynamics approach

Characterization of homodimer interfaces with cross-linking mass spectrometry and isotopically labeled proteins

(2018) Diogo B Lima et al.   Nature Protocols

Protein Tertiary Structure by Crosslinking/Mass Spectrometry

(2018) Michael Schneider et al.   TRENDS IN BIOCHEMICAL SCIENCES

Insertion of the Biogenesis Factor Rei1 Probes the Ribosomal Tunnel during 60S Maturation

(2016) Basil Johannes Greber et al.   CELL

Structure of the MIS12 Complex and Molecular Basis of Its Interaction with CENP-C at Human Kinetochores

(2016) Arsen Petrovic et al.   CELL

Molecular architecture of the inner ring scaffold of the human nuclear pore complex

(2016) J. Kosinski et al.   SCIENCE

Crosslinking and Mass Spectrometry: An Integrated Technology to Understand the Structure and Function of Molecular Machines

(2016) Alexander Leitner et al.   TRENDS IN BIOCHEMICAL SCIENCES

Chemical Cross-Linking/Mass Spectrometry Maps the Amyloid β Peptide Binding Region on Both Apolipoprotein E Domains

(2015) Stéphanie Deroo et al.   ACS Chemical Biology

De novo protein structure determination from near-atomic-resolution cryo-EM maps

(2015) Ray Yu-Ruei Wang et al.   NATURE METHODS

A Model of Lipid-Free Apolipoprotein A-I Revealed by Iterative Molecular Dynamics Simulation

(2015) Xing Zhang et al.   PLoS One

Molecular Architecture of the 40S⋅eIF1⋅eIF3 Translation Initiation Complex

(2014) Jan P. Erzberger et al.   CELL

The advancement of chemical cross-linking and mass spectrometry for structural proteomics: from single proteins to protein interaction networks

(2014) Andrea Sinz   Expert Review of Proteomics

The Structure of Human Apolipoprotein A-IV as Revealed by Stable Isotope-assisted Cross-linking, Molecular Dynamics, and Small Angle X-ray Scattering

(2014) Ryan G. Walker et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A mass spectrometry–based hybrid method for structural modeling of protein complexes

(2014) Argyris Politis et al.   NATURE METHODS

Apolipoprotein E: Structure and function in lipid metabolism, neurobiology, and Alzheimer's diseases

(2014) Yadong Huang et al.   NEUROBIOLOGY OF DISEASE

Distance restraints from crosslinking mass spectrometry: Mining a molecular dynamics simulation database to evaluate lysine-lysine distances

(2014) Eric D. Merkley et al.   PROTEIN SCIENCE

A Pseudo-Atomic Model for the Capsid Shell of Bacteriophage Lambda Using Chemical Cross-Linking/Mass Spectrometry and Molecular Modeling

(2013) Pragya Singh et al.   JOURNAL OF MOLECULAR BIOLOGY

Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy

(2013) Chia-Chen Liu et al.   Nature Reviews Neurology

Cross-Link Guided Molecular Modeling with ROSETTA

(2013) Abdullah Kahraman et al.   PLoS One

Concerning the structure of apoE

(2013) Carl Frieden et al.   PROTEIN SCIENCE

Cholesterol homeostasis: a key to prevent or slow down neurodegeneration

(2013) Laura Anchisi et al.   Frontiers in Physiology

False discovery rate estimation for cross-linked peptides identified by mass spectrometry

(2012) Thomas Walzthoeni et al.   NATURE METHODS

Putting the Pieces Together: Integrative Modeling Platform Software for Structure Determination of Macromolecular Assemblies

(2012) Daniel Russel et al.   PLOS BIOLOGY

The Structure, Dynamics, and Binding of the LA45 Module Pair of the Low-Density Lipoprotein Receptor Suggest an Important Role for LA4 in Ligand Release

(2011) Miklos Guttman et al.   BIOCHEMISTRY

Hydrogen/Deuterium Exchange and Electron-Transfer Dissociation Mass Spectrometry Determine the Interface and Dynamics of Apolipoprotein E Oligomerization

(2011) Richard Y-C. Huang et al.   BIOCHEMISTRY

Fluid phase lipid areas and bilayer thicknesses of commonly used phosphatidylcholines as a function of temperature

(2011) Norbert Kučerka et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Regulation of cholesterol homeostasis

(2011) Leigh Goedeke et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Apolipoprotein A-I structural organization in high-density lipoproteins isolated from human plasma

(2011) Rong Huang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Topology of human apolipoprotein E3 uniquely regulates its diverse biological functions

(2011) J. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of the Minimal Interface Between ApoE and LRP

(2010) Miklos Guttman et al.   JOURNAL OF MOLECULAR BIOLOGY

The HADDOCK web server for data-driven biomolecular docking

(2010) Sjoerd J de Vries et al.   Nature Protocols

Apolipoprotein E: From lipid transport to neurobiology

(2010) Paul S. Hauser et al.   PROGRESS IN LIPID RESEARCH

Apolipoprotein E: structure determines function, from atherosclerosis to Alzheimer's disease to AIDS

(2008) Robert W. Mahley et al.   JOURNAL OF LIPID RESEARCH

Insight on the Molecular Envelope of Lipid-Bound Apolipoprotein E from Electron Paramagnetic Resonance Spectroscopy

(2008) Danny M. Hatters et al.   JOURNAL OF MOLECULAR BIOLOGY

United-Atom Acyl Chains for CHARMM Phospholipids

(2008) Jérôme Hénin et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Identification of cross-linked peptides from large sequence databases

(2008) Oliver Rinner et al.   NATURE METHODS