High-dimensional single-cell phenotyping reveals extensive haploinsufficiency

Global study of holistic morphological effectors in the budding yeast Saccharomyces cerevisiae

(2018) Godai Suzuki et al.   BMC GENOMICS

A global genetic interaction network maps a wiring diagram of cellular function

(2016) M. Costanzo et al.   SCIENCE

Genome-Wide Screen for Haploinsufficient Cell Size Genes in the Opportunistic Yeast Candida albicans

(2016) Julien Chaillot et al.   G3-Genes Genomes Genetics

Dominance from the perspective of gene–gene and gene–chemical interactions

(2015) Arkadiusz Gladki et al.   GENETICA

Single-cell phenomics in budding yeast

(2015) Yoshikazu Ohya et al.   MOLECULAR BIOLOGY OF THE CELL

Essential gene disruptions reveal complex relationships between phenotypic robustness, pleiotropy, and fitness

(2015) C. R. Bauer et al.   Molecular Systems Biology

Pervasive robustness in biological systems

(2015) Marie-Anne Félix et al.   NATURE REVIEWS GENETICS

Haploinsufficiency predictions without study bias

(2015) Julia Steinberg et al.   NUCLEIC ACIDS RESEARCH

qgraph: Network Visualizations of Relationships in Psychometric Data

(2015) Sacha Epskamp et al.   Journal of Statistical Software

Unveiling nonessential gene deletions that confer significant morphological phenotypes beyond natural yeast strains

(2014) Ming Yang et al.   BMC GENOMICS

Single-cell phenomics reveals intra-species variation of phenotypic noise in yeast

(2013) Gaël Yvert et al.   BMC Systems Biology

Dynamic changes in brewing yeast cells in culture revealed by statistical analyses of yeast morphological data

(2013) Shinsuke Ohnuki et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Vanillin Inhibits Translation and Induces Messenger Ribonucleoprotein (mRNP) Granule Formation in Saccharomyces cerevisiae: Application and Validation of High-Content, Image-Based Profiling

(2013) Aya Iwaki et al.   PLoS One

Comprehensive data-driven analysis of the impact of chemoinformatic structure on the genome-wide biological response profiles of cancer cells to 1159 drugs

(2012) Suleiman A Khan et al.   BMC BIOINFORMATICS

Identification of dosage-sensitive genes in Saccharomyces cerevisiae using the genetic tug-of-war method

(2012) K. Makanae et al.   GENOME RESEARCH

Conserved rules govern genetic interaction degree across species

(2012) Elizabeth N Koch et al.   GENOME BIOLOGY

Systematic exploration of essential yeast gene function with temperature-sensitive mutants

(2011) Zhijian Li et al.   NATURE BIOTECHNOLOGY

Integrating gene expression and GO classification for PCA by preclustering

(2010) Jorn R De Haan et al.   BMC BIOINFORMATICS

Quantitative analysis of fitness and genetic interactions in yeast on a genome scale

(2010) Anastasia Baryshnikova et al.   NATURE METHODS

High-Content, Image-Based Screening for Drug Targets in Yeast

(2010) Shinsuke Ohnuki et al.   PLoS One

Characterising and Predicting Haploinsufficiency in the Human Genome

(2010) Ni Huang et al.   PLoS Genetics

Identification of human haploinsufficient genes and their genomic proximity to segmental duplications

(2008) Vinh T Dang et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

A comprehensive strategy enabling high-resolution functional analysis of the yeast genome

(2008) David K Breslow et al.   NATURE METHODS

Up-to-date catalogues of yeast protein complexes

(2008) Shuye Pu et al.   NUCLEIC ACIDS RESEARCH

The Chemical Genomic Portrait of Yeast: Uncovering a Phenotype for All Genes

(2008) M. E. Hillenmeyer et al.   SCIENCE