A central-acting connexin inhibitor, INI-0602, prevents high-fat diet-induced feeding pattern disturbances and obesity in mice

Neural and Molecular Mechanisms Involved in Controlling the Quality of Feeding Behavior: Diet Selection and Feeding Patterns

(2017) Tsutomu Sasaki   Nutrients

Astrocyte IKKβ/NF-κB signaling is required for diet-induced obesity and hypothalamic inflammation

(2017) J.D. Douglass et al.   Molecular Metabolism

New tools for studying microglia in the mouse and human CNS

(2016) Mariko L. Bennett et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Daily Eating Patterns and Their Impact on Health and Disease

(2016) Amir Zarrinpar et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

N-methyl-d-aspartate receptor coagonist d-serine suppresses intake of high-preference food

(2015) Tsutomu Sasaki et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Overexpression of insulin receptor partially improves obese and diabetic phenotypes in db/db mice

(2015) Tsutomu Sasaki et al.   ENDOCRINE JOURNAL

Disruption of Daily Rhythms by High-Fat Diet Is Reversible

(2015) Katrina L. Branecky et al.   PLoS One

Circadian insights into dopamine mechanisms

(2014) J. Mendoza et al.   NEUROSCIENCE

Gap junctions and hemichannels composed of connexins: potential therapeutic targets for neurodegenerative diseases

(2014) Hideyuki Takeuchi et al.   Frontiers in Cellular Neuroscience

Regulation of gap junction channels by infectious agents and inflammation in the CNS

(2014) Paul Castellano et al.   Frontiers in Cellular Neuroscience

Microglia Dictate the Impact of Saturated Fat Consumption on Hypothalamic Inflammation and Neuronal Function

(2014) Martin Valdearcos et al.   Cell Reports

Hypothalamic SIRT1 prevents age-associated weight gain by improving leptin sensitivity in mice

(2013) Tsutomu Sasaki et al.   DIABETOLOGIA

High-fat diet acutely affects circadian organisation and eating behavior

(2013) Julie S. Pendergast et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Timing of food intake predicts weight loss effectiveness

(2013) M Garaulet et al.   INTERNATIONAL JOURNAL OF OBESITY

The NPY intergeniculate leaflet projections to the suprachiasmatic nucleus transmit metabolic conditions

(2013) N. Saderi et al.   NEUROSCIENCE

High Caloric intake at breakfast vs. dinner differentially influences weight loss of overweight and obese women

(2013) Daniela Jakubowicz et al.   Obesity

Leptin-sensitive neurons in the arcuate nuclei contribute to endogenous feeding rhythms

(2012) Ai-Jun Li et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Time-Restricted Feeding without Reducing Caloric Intake Prevents Metabolic Diseases in Mice Fed a High-Fat Diet

(2012) Megumi Hatori et al.   Cell Metabolism

Timed high-fat diet resets circadian metabolism and prevents obesity

(2012) Hadas Sherman et al.   FASEB JOURNAL

The Role of Gap Junction Channels During Physiologic and Pathologic Conditions of the Human Central Nervous System

(2012) Eliseo A. Eugenin et al.   Journal of Neuroimmune Pharmacology

Consumption of a high-fat diet, but not regular endurance exercise training, regulates hypothalamic lipid accumulation in mice

(2012) Melissa L. Borg et al.   JOURNAL OF PHYSIOLOGY-LONDON

Obesity is associated with hypothalamic injury in rodents and humans

(2011) Joshua P. Thaler et al.   JOURNAL OF CLINICAL INVESTIGATION

Blockade of Gap Junction Hemichannel Suppresses Disease Progression in Mouse Models of Amyotrophic Lateral Sclerosis and Alzheimer's Disease

(2011) Hideyuki Takeuchi et al.   PLoS One

Induction of Hypothalamic Sirt1 Leads to Cessation of Feeding via Agouti-Related Peptide

(2010) Tsutomu Sasaki et al.   ENDOCRINOLOGY

Time-of-day-dependent dietary fat consumption influences multiple cardiometabolic syndrome parameters in mice

(2010) M S Bray et al.   INTERNATIONAL JOURNAL OF OBESITY

Saturated Fatty Acids Produce an Inflammatory Response Predominantly through the Activation of TLR4 Signaling in Hypothalamus: Implications for the Pathogenesis of Obesity

(2009) M. Milanski et al.   JOURNAL OF NEUROSCIENCE

A riot of rhythms: neuronal and glial circadian oscillators in the mediobasal hypothalamus

(2009) Clare Guilding et al.   Molecular Brain

Hypothalamic proinflammatory lipid accumulation, inflammation, and insulin resistance in rats fed a high-fat diet

(2008) Kelly A. Posey et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

High-fat feeding alters the clock synchronization to light

(2008) Jorge Mendoza et al.   JOURNAL OF PHYSIOLOGY-LONDON