Rational design, preparation and characterization of recombinant Ag85B variants and their glycoconjugates with T-cell antigenic activity against Mycobacterium tuberculosis

Application of a rapid HILIC-UV method for synthesis optimization and stability studies of immunogenic neo -glycoconjugates

(2017) F. Rinaldi et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Glycosylation of Recombinant Antigenic Proteins from Mycobacterium tuberculosis: In Silico Prediction of Protein Epitopes and Ex Vivo Biological Evaluation of New Semi-Synthetic Glycoconjugates

(2017) Teodora Bavaro et al.   MOLECULES

From new Diagnostic Targets to Recombinant Proteins and Semi-Synthetic Protein-Based Vaccines

(2016) Teodora Bavaro et al.   CURRENT ORGANIC CHEMISTRY

Convergent chemo-enzymatic synthesis of mannosylated glycopeptides; targeting of putative vaccine candidates to antigen presenting cells

(2015) Julie D. McIntosh et al.   Chemical Science

Glycoconjugate vaccines: an update

(2014) Mairi Vella et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Liquid chromatography–mass spectrometry structural characterization of neo glycoproteins aiding the rational design and synthesis of a novel glycovaccine for protection against tuberculosis

(2014) Caterina Temporini et al.   JOURNAL OF CHROMATOGRAPHY A

Characterization of Intact Neo-Glycoproteins by Hydrophilic Interaction Liquid Chromatography

(2014) Alice Pedrali et al.   MOLECULES

Infectious disease: Beating the big three

(2014) Katherine Bourzac   NATURE

Chemoenzymatic synthesis of neoglycoproteins driven by the assessment of protein surface reactivity

(2014) T. Bavaro et al.   RSC Advances

Novel Vaccination Strategies against Tuberculosis

(2014) P. Andersen et al.   Cold Spring Harbor Perspectives in Medicine

Designing Vaccines for the Twenty-First Century Society

(2014) Oretta Finco et al.   Frontiers in Immunology

The Immunodominant T-Cell Epitopes of the Mycolyl-Transferases of the Antigen 85 Complex of M. tuberculosis

(2014) Kris Huygen   Frontiers in Immunology

Modern chromatographic and mass spectrometric techniques for protein biopharmaceutical characterization

(2013) Koen Sandra et al.   JOURNAL OF CHROMATOGRAPHY A

A Vision for Vaccines Built from Fully Synthetic Tumor-Associated Antigens: From the Laboratory to the Clinic

(2013) Rebecca M. Wilson et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Optimizing Escherichia coli as a protein expression platform to produce Mycobacterium tuberculosis immunogenic proteins

(2013) Luciano Piubelli et al.   Microbial Cell Factories

Synthetically defined glycoprotein vaccines: current status and future directions

(2013) Roberto Adamo et al.   Chemical Science

Memory T Cells in Latent Mycobacterium tuberculosis Infection Are Directed against Three Antigenic Islands and Largely Contained in a CXCR3+CCR6+ Th1 Subset

(2013) Cecilia S. Lindestam Arlehamn et al.   PLoS Pathogens

A Coordinated Synthesis and Conjugation Strategy for the Preparation of Homogeneous Glycoconjugate Vaccine Candidates

(2011) Elizabeth J. Grayson et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Efficacy of a Conjugate Vaccine Containing Polymannuronic Acid and Flagellin against Experimental Pseudomonas aeruginosa Lung Infection in Mice

(2011) Victoria L. Campodónico et al.   INFECTION AND IMMUNITY

Intact protein analysis in the biopharmaceutical field

(2011) Aline Staub et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

A multistage tuberculosis vaccine that confers efficient protection before and after exposure

(2011) Claus Aagaard et al.   NATURE MEDICINE

Carbohydrate vaccines: developing sweet solutions to sticky situations?

(2010) Rena D. Astronomo et al.   NATURE REVIEWS DRUG DISCOVERY

Combined Approaches to the Synthesis and Study of Glycoproteins

(2009) Gonçalo J. L. Bernardes et al.   ACS Chemical Biology

Prediction of antigenic epitopes on protein surfaces by consensus scoring

(2009) Shide Liang et al.   BMC BIOINFORMATICS

Carbohydrates: A Frontier in Medicinal Chemistry

(2009) Pierre Stallforth et al.   JOURNAL OF MEDICINAL CHEMISTRY

Biologics through Chemistry: Total Synthesis of a Proposed Dual-Acting Vaccine Targeting Ovarian Cancer by Orchestration of Oligosaccharide and Polypeptide Domains

(2009) Jianglong Zhu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

SEPPA: a computational server for spatial epitope prediction of protein antigens

(2009) Jing Sun et al.   NUCLEIC ACIDS RESEARCH

Carbohydrate-Mediated Targeting of Antigen to Dendritic Cells Leads to Enhanced Presentation of Antigen to T Cells

(2008) Eddie W. Adams et al.   CHEMBIOCHEM

Glycoprotein Synthesis: An Update

(2008) David P. Gamblin et al.   CHEMICAL REVIEWS

Mycobacterial glycoconjugates as vaccine candidates against tuberculosis

(2008) Gunilla Källenius et al.   TRENDS IN MICROBIOLOGY

Improved Protective Efficacy of a Species-Specific DNA Vaccine Encoding Mycolyl-Transferase Ag85A from Mycobacterium ulcerans by Homologous Protein Boosting

(2008) Audrey Tanghe et al.   PLoS Neglected Tropical Diseases