Glycosylation of Recombinant Antigenic Proteins from Mycobacterium tuberculosis: In Silico Prediction of Protein Epitopes and Ex Vivo Biological Evaluation of New Semi-Synthetic Glycoconjugates

From new Diagnostic Targets to Recombinant Proteins and Semi-Synthetic Protein-Based Vaccines

(2016) Teodora Bavaro et al.   CURRENT ORGANIC CHEMISTRY

Convergent chemo-enzymatic synthesis of mannosylated glycopeptides; targeting of putative vaccine candidates to antigen presenting cells

(2015) Julie D. McIntosh et al.   Chemical Science

Role of individual's T-cell immunome in controlling HIV-1 progression

(2014) Alba Grifoni et al.   IMMUNOLOGY

Liquid chromatography–mass spectrometry structural characterization of neo glycoproteins aiding the rational design and synthesis of a novel glycovaccine for protection against tuberculosis

(2014) Caterina Temporini et al.   JOURNAL OF CHROMATOGRAPHY A

Infectious disease: Beating the big three

(2014) Katherine Bourzac   NATURE

Chemoenzymatic synthesis of neoglycoproteins driven by the assessment of protein surface reactivity

(2014) T. Bavaro et al.   RSC Advances

Novel Vaccination Strategies against Tuberculosis

(2014) P. Andersen et al.   Cold Spring Harbor Perspectives in Medicine

Epitope-Specific Antibody Levels in Tuberculosis: Biomarkers of Protection, Disease, and Response to Treatment

(2014) Graham H. Bothamley   Frontiers in Immunology

Functional Signatures of Human CD4 and CD8 T Cell Responses to Mycobacterium tuberculosis

(2014) Teresa Prezzemolo et al.   Frontiers in Immunology

Biomarkers of tuberculosis: a research roadmap

(2013) Hilary S Whitworth et al.   Biomarkers in Medicine

Optimizing Escherichia coli as a protein expression platform to produce Mycobacterium tuberculosis immunogenic proteins

(2013) Luciano Piubelli et al.   Microbial Cell Factories

Reliable B Cell Epitope Predictions: Impacts of Method Development and Improved Benchmarking

(2012) Jens Vindahl Kringelum et al.   PLoS Computational Biology

A Coordinated Synthesis and Conjugation Strategy for the Preparation of Homogeneous Glycoconjugate Vaccine Candidates

(2011) Elizabeth J. Grayson et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Functional classification of class II human leukocyte antigen (HLA) molecules reveals seven different supertypes and a surprising degree of repertoire sharing across supertypes

(2011) Jason Greenbaum et al.   IMMUNOGENETICS

Carbohydrate vaccines: developing sweet solutions to sticky situations?

(2010) Rena D. Astronomo et al.   NATURE REVIEWS DRUG DISCOVERY

Serodiagnosis of tuberculous lymphadenitis using a combination of antigens

(2010) Demissew Beyene et al.   Journal of Infection in Developing Countries

Combined Approaches to the Synthesis and Study of Glycoproteins

(2009) Gonçalo J. L. Bernardes et al.   ACS Chemical Biology

Prediction of antigenic epitopes on protein surfaces by consensus scoring

(2009) Shide Liang et al.   BMC BIOINFORMATICS

Biologics through Chemistry: Total Synthesis of a Proposed Dual-Acting Vaccine Targeting Ovarian Cancer by Orchestration of Oligosaccharide and Polypeptide Domains

(2009) Jianglong Zhu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

SEPPA: a computational server for spatial epitope prediction of protein antigens

(2009) Jing Sun et al.   NUCLEIC ACIDS RESEARCH

CD4 and CD8 T Cell Responses to the M. tuberculosis Ag85B-TB10.4 Promoted by Adjuvanted Subunit, Adenovector or Heterologous Prime Boost Vaccination

(2009) Tara Elvang et al.   PLoS One

Design of immunogenic peptides from Mycobacterium tuberculosis genes expressed during macrophage infection

(2009) Fouad Seghrouchni et al.   TUBERCULOSIS

ElliPro: a new structure-based tool for the prediction of antibody epitopes

(2008) Julia Ponomarenko et al.   BMC BIOINFORMATICS

Carbohydrate-Mediated Targeting of Antigen to Dendritic Cells Leads to Enhanced Presentation of Antigen to T Cells

(2008) Eddie W. Adams et al.   CHEMBIOCHEM

Glycoprotein Synthesis: An Update

(2008) David P. Gamblin et al.   CHEMICAL REVIEWS

Evaluation of a recombinant BCG expressing antigen Ag85B and PPE protein Rv3425 from DNA segment RD11 of Mycobacterium tuberculosis in C57BL/6 mice

(2008) Jiu ling Wang et al.   MEDICAL MICROBIOLOGY AND IMMUNOLOGY

Mycobacterial glycoconjugates as vaccine candidates against tuberculosis

(2008) Gunilla Källenius et al.   TRENDS IN MICROBIOLOGY