Article
Chemistry, Multidisciplinary
Shanshan Wu, Meizhou Zhang, Jie Song, Stefan Weber, Xiaoguo Liu, Chunhai Fan, Yuzhou Wu
Summary: Calcium phosphate is the most abundant biomineral in hard tissues, and the rational design and fabrication of Ca-P materials have been achieved through a particle attachment process, inheriting structural details encoded by DNA templates to enhance mechanical strength while preserving synthetic functionalities on the DNA surface.
Article
Chemistry, Physical
Jihye Lee, Adama Konate, Clement Guibert, Jessem Landoulsi
Summary: In this study, a biomimetic method for growing a hybrid calcium phosphate (CaP) - collagen coating is described. The versatility of layer-by-layer (LbL) method is explored to incorporate collagen and alkaline phosphatase (ALP), and control their organization and bioactivity. The presence of collagen fibrils in the LbL film plays a crucial role in the growth mechanism of the biomimetic mineral layer. The approach provides a straightforward way for designing biomimetic hybrid coatings in biomedical applications.
SURFACES AND INTERFACES
(2023)
Article
Biochemistry & Molecular Biology
Lucas Fabricio Bahia Nogueira, Marcos Antonio Eufrasio Cruz, Guilherme Jose Aguilar, Delia Rita Tapia-Blacido, Marcia Eliana da Silva Ferreira, Bianca Chieregato Maniglia, Massimo Bottini, Pietro Ciancaglini, Ana Paula Ramos
Summary: Inspired by collagen fibrils, this study compares two methods to synthesize bioactive hybrid membranes and assesses the role of the organic matrix in mineral phase deposition. The hybrid membranes have uniform mineral particle dispersion and enhanced mechanical properties. They are bioactive, non-toxic to osteoblasts, and display antibacterial action against pathogenic microorganisms. These findings have potential for developing bioactive hybrid membranes with controllable degradation rates and antimicrobial properties.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Chemistry, Multidisciplinary
Susrut Akkineni, Gregory S. Doerk, Chenyang Shi, Biao Jin, Shuai Zhang, Stefan Habelitz, James J. De Yoreo
Summary: The study demonstrates how the supramolecular structures of matrix proteins can be synthetically directed into predetermined patterns while retaining their functionality. They used block copolymer lamellar patterns to direct the assembly of peptide nanoribbons, which template calcium phosphate nucleation by creating a low-energy interface. The results show that the patterned nanoribbons maintain their structure and function, and successfully direct the formation of calcium phosphate with high fidelity.
Review
Biochemistry & Molecular Biology
Clement Guibert, Jessem Landoulsi
Summary: Biomineralization is the process by which organisms produce hard inorganic matter from soft tissues, with sophisticated toolkit and biological system regulation in place. Two main views have emerged regarding the mechanism of CaP biomineralization, with one focusing on in vivo systems and the other on physicochemistry research.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Nanoscience & Nanotechnology
Yuzhu Yao, Puze Li, Junkai He, Dongdong Wang, Jun Hu, Xiangliang Yang
Summary: In this study, Bi2Se3-MnO2@BSA nanocomposites were successfully prepared via biomineralization, with Bi2Se3 and MnO2 acting as radiosensitizers and oxygen enhancers to improve tumor radiosensitivity. BSA templating provided high biocompatibility and stability to the nanocomposites, enhancing the efficacy of radiotherapy.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Chemistry, Multidisciplinary
Min-juan Shen, Kai Jiao, Chen-yu Wang, Hermann Ehrlich, Mei-chen Wan, Dong-xiao Hao, Jing Li, Qian-qian Wan, Lige Tonggu, Jian-fei Yan, Kai-yan Wang, Yu-xuan Ma, Ji-Hua Chen, Franklin R. Tay, Li-na Niu
Summary: The text discusses the role of extracellular DNA in collagen mineralization and its potential application in treating diseases associated with ectopic mineralization. It highlights how extracellular DNA stabilizes calcium phosphate solution and triggers mineralization of collagen, providing a biomimetic approach to fabricating inorganic-organic hybrid materials for tissue engineering.
Article
Engineering, Biomedical
Huaixin Zhao, Jigang Lv, Feng Li, Zhili Zhang, Chunzhi Zhang, Zi Gu, Dayong Yang
Summary: The study demonstrated the preparation of DNA-Mn hybrid nanoflower (DMNF) using manganese ions mediated enzymatic biomineralization, with controllable morphology and size. Encoding aptamer sequence into the template achieved tumor-targeted imaging, showing enhanced magnetic resonance imaging effect in an acidic environment.
Article
Engineering, Environmental
Miaorong Zhang, Yan Zhang, Chuankai Yang, Chunyun Ma, Jianguo Tang
Summary: Enzyme-inorganic hybrid nanoflowers (HNFs) are a novel hybrid nanomaterial with superior performances, involving classification, synthesis, functionalization, and various potential application areas. The focus of the review is on developing classification, synthesis methods and applications of enzyme-inorganic HNFs in the field of biocatalysis. Current problems and prospects for further study are proposed.
CHEMICAL ENGINEERING JOURNAL
(2021)
Article
Biophysics
Yuanda Liu, Jing Wang, Ming Jiang, Xueyan Li, Qinghao Zhang, Hongyan He
Summary: In this study, a hybrid membrane with biomimetic function was developed to create an angiogenesis-inductive microenvironment through the release of calcium ions, aiming to overcome the limitations of bone tissue regeneration in diabetic patients. The results showed that the hybrid membrane can enhance vascularization and bone regeneration by recruiting, proliferating, and differentiating mesenchymal stem cells and endothelial progenitors.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2022)
Article
Materials Science, Biomaterials
Zhongcheng Li, Qian Ren, Sili Han, Longjiang Ding, Xi Qin, Die Hui, Ting Het, Tian Tian, Ziqian Lu, Linglin Zhang
Summary: The study demonstrated the promoting effect of ID8 on the intrafibrillar mineralization of collagen, achieved through its self-assembly ability and calcium responsiveness. It enhanced intermolecular hydrogen bonding and significantly increased the hydrophilicity of collagen. Peptides with self-assembly properties like ID8 are expected to be potential tools for biomimetic mineralization of collagen.
REGENERATIVE BIOMATERIALS
(2022)
Article
Materials Science, Multidisciplinary
Ye Zhang, Ying Huang, Yanyun Pang, Zihui Zhu, Yuchen Zhang, Qing Liu, Xu Zhang, Ying Liu
Summary: This study utilized proanthocyanidins to simulate the bioactivities of glycosaminoglycans, achieving significant effects in promoting dentine remineralization by reconstructing interfibrillar bridges of the collagen network. This strategy not only improved the mechanical properties of demineralized dentine, but also exhibited antibacterial effects, providing new clinical opportunities for the effective treatment of dentine caries.
MATERIALS & DESIGN
(2021)
Article
Engineering, Environmental
Zhijing Wu, Xiangping Li, Huosheng Li, Gaosheng Zhang
Summary: Phosphorus is essential for biological growth, but its excessive presence can lead to eutrophication. The novel zero-valent manganese sorbent Mn-0@Mn2O3 shows exceptional phosphate removal performance, making it promising for phosphate removal from real municipal wastewater.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2021)
Article
Engineering, Environmental
Bo Zhao, Kai Zheng, Chunguang Liu
Summary: The study on the dissolution and toxicity of copper phosphate hybrid nanoflowers under bacterial action demonstrated the process of change throughout its life cycle and its impact on bacteria.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Article
Chemistry, Multidisciplinary
Robin H. M. van der Meijden, Deniz Daviran, Luco Rutten, X. Frank Walboomers, Elena Macias-Sanchez, Nico Sommerdijk, Anat Akiva
Summary: Osteons are cylindrical structures composed of layers of mineralized collagen fibrils, called lamellae, which make up the main organizational components of human compact bone. Recent in vitro studies question the involvement of cells in matrix mineralization and suggest that it may be driven solely by interactions between minerals and extracellular matrix. Cell-free in vitro systems have demonstrated the complete multiscale reconstruction of the osteon's 3D structure and composition, and have been explored as realistic models for studying matrix-controlled mineralization processes. Raman and electron microscopy indicate that glycosaminoglycans play a more significant role in matrix-mineral interactions than previously assumed, and collagen organization is influenced by its interaction with developing minerals.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Article
Chemistry, Physical
Min Lu, Li An, Jie Yin, Jing Jin, Rui Yang, Bolong Huang, Yang Hu, Yong-Qing Zhao, Pinxian Xi
Summary: In this study, electronically engineered amorphous Fe-Co-S sites embedded in Prussian blue analogue were found to enhance electron transfer and alleviate the overbinding effect of OH* during the electrochemical oxygen evolution reaction (OER) in aluminium-air batteries. The resulting hybrid system exhibited optimized electronic structure and showed high energy density and stability in a flexible Al-air battery.
JOURNAL OF MATERIALS CHEMISTRY A
(2022)
Article
Nanoscience & Nanotechnology
Yicheng Wei, Yao Zheng, Yang Hu, Bolong Huang, Mingzi Sun, Pengfei Da, Pinxian Xi, Chun-Hua Yan
Summary: This study demonstrates the artificial construction of a heterostructure to control the active site formation and reconstruction in perovskite oxides, leading to improved oxygen evolution reaction (OER) activity.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Chemistry, Multidisciplinary
Li An, Yang Hu, Jianyi Li, Jiamin Zhu, Mingzi Sun, Bolong Huang, Pinxian Xi, Chun-Hua Yan
Summary: A surface evolution strategy was applied to change the surface structure of MnCo2O4 oxide, allowing for the switching of reaction pathways from 2e(-) ORR to 4e(-) ORR. Different surface configurations of MnCo2O4 were found to exhibit excellent performance in the oxygen reduction reaction.
ADVANCED MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Meng Tian, Shanshan Wu, Yang Hu, Zhaori Mu, Zhi Li, Yichao Hou, Pinxian Xi, Chun-Hua Yan
Summary: Electrocatalytic reduction of CO2 to formate is a promising method for carbon neutrality, and introducing heteroatoms can enhance catalytic activity and selectivity. However, the structural reconstruction behavior of catalysts driven by voltage is often overlooked. In this study, Cu/Bi2S3 was used as a model to investigate the dynamic reduction process in different atmospheric environments. The catalyst exhibited excellent faradaic efficiency for formate, long-term stability, and high current density in a flow cell. Experimental results and theoretical calculations revealed that the introduction of copper enhanced CO2 adsorption, accelerated charge transfer, and reduced the formation barrier of *OCHO, promoting formate formation. This work highlights the importance of considering the effects of saturated gases during structural evolution and provides insight for designing highly active catalysts.
Article
Chemistry, Inorganic & Nuclear
Shanshan Wu, Meng Tian, Yang Hu, Nan Zhang, Wei Shen, Jianyi Li, Linchuan Guo, Pengfei Da, Pinxian Xi, Chun-Hua Yan
Summary: A CeO2 modification strategy is proposed to improve the selectivity of catalysts for formate by tuning the *OCHO intermediate, which is crucial for formate production.
INORGANIC CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Zi Yang, Deguang Ji, Zhi Li, Zidong He, Yang Hu, Jie Yin, Yichao Hou, Pinxian Xi, Chun-Hua Yan
Summary: In this study, cerium is utilized as a self-sacrificing agent to stabilize Cu+ of CuS, resulting in high selectivity for ethanol production during the electrochemical CO2 reduction.
Article
Multidisciplinary Sciences
Jie Yin, Jing Jin, Zhouyang Yin, Liu Zhu, Xin Du, Yong Peng, Pinxian Xi, Chun-Hua Yan, Shouheng Sun
Summary: The FeN/Fe3N interface with Fe-N-4 and Fe-N-2 coordination sites is revealed to enhance the electrochemical reduction of CO2 to CO.
NATURE COMMUNICATIONS
(2023)
Article
Biochemistry & Molecular Biology
Caihong Fu, Shuangni Shi, Nannan Wei, Yirui Fan, Hong Gu, Peng Liu, Jianxi Xiao
Summary: We developed biocompatible and nonirritating triple-helical recombinant collagen (THRC) dressings for accelerated healing of microneedle-injured and photodamaged acute skin wounds. The THRC dressings exhibited superior biocompatibility and bioactivity, significantly promoting the proliferation and adhesion of fibroblasts. In vivo studies demonstrated that the THRC dressings effectively healed damaged dermis and accelerated re-epithelialization and collagen deposition.
Article
Chemistry, Multidisciplinary
Jean Claude Munyemana, Huixia He, Caihong Fu, Yirui Fan, Xiuxia Sun, Jianxi Xiao
Summary: In this study, well-ordered porous calcium carbonate nanospheres were synthesized using recombinant collagen as a biomineralization template. The recombinant collagen played a crucial role in modulating the morphology and crystallinity of the calcium carbonate nanoparticles. This study provides a promising avenue for the production of novel organic-inorganic nanostructures with potential applications in drug delivery.
Article
Chemistry, Multidisciplinary
Shao-Wen Xu, Jianyi Li, Nan Zhang, Wei Shen, Yao Zheng, Pinxian Xi
Summary: Hydrogen production through electrocatalytic seawater splitting offers a promising solution for sustainable energy generation. However, the complex composition of seawater presents challenges in terms of electrode side reactions and corrosion. This review discusses the basic principles of seawater electrolysis and highlights recent progress in designing efficient systems, including catalyst design, electrolyser assembly, membrane regulation, and electrolyte engineering. The challenges and future opportunities for large-scale hydrogen production from seawater splitting are also emphasized.
CHEMICAL COMMUNICATIONS
(2023)
Article
Materials Science, Biomaterials
Jianan Li, Wenjie Huang, Huixia He, Shuangni Shi, Xiuxia Sun, Jianxi Xiao
Summary: Prolonged exposure to UV radiation can lead to severe photodamage to the skin, causing abnormal fragmentation of elastin fibers. Traditional animal-derived elastin has limitations such as virus transmission risk, degradation, and quality control challenges. This study developed a novel recombinant fusion elastin and its cross-linked hydrogel for improved healing efficacy for UV-irradiated skin.
JOURNAL OF MATERIALS CHEMISTRY B
(2023)
Article
Chemistry, Multidisciplinary
Zhao Liu, Linge Nian, Xiangdong Cai, Yue Hu, Junqiang Lei, Jianxi Xiao
Summary: We have developed a stable MRI peptide contrast agent, Gd-ICTP, which exhibits excellent selectivity for type I collagen. This agent allows accurate and non-invasive detection of hepatic fibrosis in vivo.
CHEMICAL COMMUNICATIONS
(2023)
Article
Materials Science, Multidisciplinary
Wenyu Wei, Manman He, Jianrui Ma, Yirui Fan, Peng Liu, Jianxi Xiao
Summary: Protein-inorganic hybrid nanomaterials combine the advantages of inorganic and organic polymers and nanomaterials. A simple one-pot method was developed to synthesize protein-rare earth fluoride nanoflowers using proteins and lanthanide fluorides. These nanoflowers exhibit high performance in maintaining enzyme stability and catalytic activity, and have finely tunable luminescence properties. The protein-templated biomineralization strategy provides a universal and robust approach for their synthesis. These novel luminescent nanoflowers have promising applications in biosensing, biocatalysis, and medical diagnostics and treatment.
MATERIALS ADVANCES
(2023)
Article
Materials Science, Multidisciplinary
Huixia He, Lili Wang, Xiangdong Cai, Qi Wang, Peng Liu, Jianxi Xiao
Summary: In this study, a biomimetic collagen composite matrix-hydroxyapatite scaffold was developed for the first time, which closely resembles the composition and structure of natural bone. The scaffold showed excellent biocompatibility and osteogenic differentiation capability, and significantly enhanced bone regeneration in rat models.
MATERIALS & DESIGN
(2023)
Article
Chemistry, Multidisciplinary
Ebtihaj Mohammed Sullam, Khalid Mohammed Adam, Stanislas Nsanzamahoro, Muzi Cai, Zixi Gao, Juanjuan Liu, Hongli Chen, Jianxi Xiao
Summary: This study presents an efficient and selective detection method for nitro explosive 2,4,6-trinitrophenol (TNP) in water using bright cyan-blue emitting colloidal poly(vinylpyrrolidone)-encapsulated silicon quantum dots (PVP-Si QDs) as a fluorescent probe. The PVP-Si QDs show a high selectivity for TNP over other molecules and ions, and exhibit excellent linear fluorescence quenching effect towards TNP with a low detection limit. The sensing mechanism combines the inner filter effect (IFE) and static quenching effect (SQE), enabling the quantification of trace amounts of TNP in real water and fish tissue samples.
NEW JOURNAL OF CHEMISTRY
(2022)