Microbiota derived short chain fatty acids promote histone crotonylation in the colon through histone deacetylases

Prophylactic Supplementation of Bifidobacterium longum 51A Protects Mice from Ovariectomy-Induced Exacerbated Allergic Airway Inflammation and Airway Hyperresponsiveness

(2017) Eduardo Mendes et al.   Frontiers in Microbiology

Inhibition of histone deacetylases in cancer therapy: lessons from leukaemia

(2016) Elena Ceccacci et al.   BRITISH JOURNAL OF CANCER

From Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites

(2016) Ara Koh et al.   CELL

YEATS2 is a selective histone crotonylation reader

(2016) Dan Zhao et al.   CELL RESEARCH

Metabolic Regulation of Gene Expression by Histone Lysine β-Hydroxybutyrylation

(2016) Zhongyu Xie et al.   MOLECULAR CELL

Dynamic Competing Histone H4 K5K8 Acetylation and Butyrylation Are Hallmarks of Highly Active Gene Promoters

(2016) Afsaneh Goudarzi et al.   MOLECULAR CELL

Diet-Microbiota Interactions Mediate Global Epigenetic Programming in Multiple Host Tissues

(2016) Kimberly A. Krautkramer et al.   MOLECULAR CELL

Molecular Coupling of Histone Crotonylation and Active Transcription by AF9 YEATS Domain

(2016) Yuanyuan Li et al.   MOLECULAR CELL

Selective recognition of histone crotonylation by double PHD fingers of MOZ and DPF2

(2016) Xiaozhe Xiong et al.   Nature Chemical Biology

The Taf14 YEATS domain is a reader of histone crotonylation

(2016) Forest H Andrews et al.   Nature Chemical Biology

The Perseus computational platform for comprehensive analysis of (prote)omics data

(2016) Stefka Tyanova et al.   NATURE METHODS

The MaxQuant computational platform for mass spectrometry-based shotgun proteomics

(2016) Stefka Tyanova et al.   Nature Protocols

Metabolic regulation of gene expression through histone acylations

(2016) Benjamin R. Sabari et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The neuropharmacology of butyrate: The bread and butter of the microbiota-gut-brain axis?

(2016) Roman M. Stilling et al.   NEUROCHEMISTRY INTERNATIONAL

HDACs and HDAC Inhibitors in Cancer Development and Therapy

(2016) Yixuan Li et al.   Cold Spring Harbor Perspectives in Medicine

Epigenetics and Metabolism

(2015) S. T. Keating et al.   CIRCULATION RESEARCH

Intracellular Crotonyl-CoA Stimulates Transcription through p300-Catalyzed Histone Crotonylation

(2015) Benjamin R. Sabari et al.   MOLECULAR CELL

Visualization of LC-MS/MS proteomics data in MaxQuant

(2015) Stefka Tyanova et al.   PROTEOMICS

Dietary Gut Microbial Metabolites, Short-chain Fatty Acids, and Host Metabolic Regulation

(2015) Mayu Kasubuchi et al.   Nutrients

Improved bottom-up strategy to efficiently separate hypermodified histone peptides through ultra-HPLC separation on a bench top Orbitrap instrument

(2014) Monica Soldi et al.   PROTEOMICS

Growing Self-Organizing Mini-Guts from a Single Intestinal Stem Cell: Mechanism and Applications

(2013) T. Sato et al.   SCIENCE

Histone deacetylases 1 and 2 maintain S-phase chromatin and DNA replication fork progression

(2013) Srividya Bhaskara et al.   Epigenetics & Chromatin

Protein Lysine Acylation and Cysteine Succination by Intermediates of Energy Metabolism

(2012) Hening Lin et al.   ACS Chemical Biology

Profiling of Substrates for Zinc-dependent Lysine Deacylase Enzymes: HDAC3 Exhibits Decrotonylase Activity In Vitro

(2012) Andreas S. Madsen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Assembling chromatin: The long and winding road

(2011) Anthony T. Annunziato   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Synthesis and biochemical analysis of 2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoro-N-hydroxy-octanediamides as inhibitors of human histone deacetylases

(2011) Leonhard M. Henkes et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Identification of 67 Histone Marks and Histone Lysine Crotonylation as a New Type of Histone Modification

(2011) Minjia Tan et al.   CELL

The Microbiome and Butyrate Regulate Energy Metabolism and Autophagy in the Mammalian Colon

(2011) Dallas R. Donohoe et al.   Cell Metabolism

SILAC-based proteomic analysis to dissect the “histone modification signature” of human breast cancer cells

(2010) Alessandro Cuomo et al.   AMINO ACIDS

Hdac3 Is Essential for the Maintenance of Chromatin Structure and Genome Stability

(2010) Srividya Bhaskara et al.   CANCER CELL

Quantitative Mass Spectrometry of Histones H3.2 and H3.3 inSuz12-deficient Mouse Embryonic Stem Cells Reveals Distinct, Dynamic Post-translational Modifications at Lys-27 and Lys-36

(2010) Hye Ryung Jung et al.   MOLECULAR & CELLULAR PROTEOMICS

Replication Stress Interferes with Histone Recycling and Predeposition Marking of New Histones

(2010) Zuzana Jasencakova et al.   MOLECULAR CELL

Isoform-specific histone deacetylase inhibitors: The next step?

(2009) Sriram Balasubramanian et al.   CANCER LETTERS

Global Histone H4 Acetylation and HDAC2 Expression in Colon Adenoma and Carcinoma

(2008) Hassan Ashktorab et al.   DIGESTIVE DISEASES AND SCIENCES