Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants

Two Novel Susceptibility Loci for Prostate Cancer in Men of African Ancestry

(2017) David V Conti et al.   JNCI-Journal of the National Cancer Institute

Two Novel Susceptibility Loci for Prostate Cancer in Men of African Ancestry

(2017) David V Conti et al.   JNCI-Journal of the National Cancer Institute

FINEMAP: efficient variable selection using summary data from genome-wide association studies

(2016) Christian Benner et al.   BIOINFORMATICS

The OncoArray Consortium: A Network for Understanding the Genetic Architecture of Common Cancers

(2016) Christopher I. Amos et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

JAM: A Scalable Bayesian Framework for Joint Analysis of Marginal SNP Effects

(2016) Paul J. Newcombe et al.   GENETIC EPIDEMIOLOGY

Incorporating Functional Annotations for Fine-Mapping Causal Variants in a Bayesian Framework Using Summary Statistics

(2016) W. Chen et al.   GENETICS

Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Cancer

(2016) Colin C. Pritchard et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cistrome Data Browser: a data portal for ChIP-Seq and chromatin accessibility data in human and mouse

(2016) Shenglin Mei et al.   NUCLEIC ACIDS RESEARCH

Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

(2015) Bjarni J. Vilhjálmsson et al.   AMERICAN JOURNAL OF HUMAN GENETICS

LocusExplorer: a user-friendly tool for integrated visualization of human genetic association data and biological annotations

(2015) Tokhir Dadaev et al.   BIOINFORMATICS

Fast and efficient QTL mapper for thousands of molecular phenotypes

(2015) Halit Ongen et al.   BIOINFORMATICS

Fine Mapping Causal Variants with an Approximate Bayesian Method Using Marginal Test Statistics

(2015) Wenan Chen et al.   GENETICS

Integration of multiethnic fine-mapping and genomic annotation to prioritize candidate functional SNPs at prostate cancer susceptibility regions

(2015) Ying Han et al.   HUMAN MOLECULAR GENETICS

Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans

(2015) Ali Amin Al Olama et al.   HUMAN MOLECULAR GENETICS

CAUSEL: an epigenome- and genome-editing pipeline for establishing function of noncoding GWAS variants

(2015) Sándor Spisák et al.   NATURE MEDICINE

Genomic variant annotation and prioritization with ANNOVAR and wANNOVAR

(2015) Hui Yang et al.   Nature Protocols

Dissection of a Complex Disease Susceptibility Region Using a Bayesian Stochastic Search Approach to Fine Mapping

(2015) Chris Wallace et al.   PLoS Genetics

Fine Mapping Causal Variants with an Approximate Bayesian Method Using Marginal Test Statistics

(2015) Wenan Chen et al.   GENETICS

Joint Analysis of Functional Genomic Data and Genome-wide Association Studies of 18 Human Traits

(2014) Joseph K. Pickrell   AMERICAN JOURNAL OF HUMAN GENETICS

Translating genetic risk factors for prostate cancer to the clinic: 2013 and beyond

(2014) Christos Mikropoulos et al.   Future Oncology

Reconfiguration of nucleosome-depleted regions at distal regulatory elements accompanies DNA methylation of enhancers and insulators in cancer

(2014) Phillippa C. Taberlay et al.   GENOME RESEARCH

Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33

(2014) Z. Wang et al.   HUMAN MOLECULAR GENETICS

Genetic and epigenetic fine mapping of causal autoimmune disease variants

(2014) Kyle Kai-How Farh et al.   NATURE

A general framework for estimating the relative pathogenicity of human genetic variants

(2014) Martin Kircher et al.   NATURE GENETICS

A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer

(2014) Ali Amin Al Olama et al.   NATURE GENETICS

Fine-Mapping the HOXB Region Detects Common Variants Tagging a Rare Coding Allele: Evidence for Synthetic Association in Prostate Cancer

(2014) Edward J. Saunders et al.   PLoS Genetics

Integrating Functional Data to Prioritize Causal Variants in Statistical Fine-Mapping Studies

(2014) Gleb Kichaev et al.   PLoS Genetics

Fine-mapping identifies multiple prostate cancer risk loci at 5p15, one of which associates with TERT expression

(2013) Zsofia Kote-Jarai et al.   HUMAN MOLECULAR GENETICS

Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array

(2013) Rosalind A Eeles et al.   NATURE GENETICS

miRBase: annotating high confidence microRNAs using deep sequencing data

(2013) Ana Kozomara et al.   NUCLEIC ACIDS RESEARCH

Investigation of the Relationship Between Prostate Cancer andMSMBandNCOA4Genetic Variants and Protein Expression

(2012) Liesel M. FitzGerald et al.   HUMAN MUTATION

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

The accessible chromatin landscape of the human genome

(2012) Robert E. Thurman et al.   NATURE

Common variants at 11q12, 10q26 and 3p11.2 are associated with prostate cancer susceptibility in Japanese

(2012) Shusuke Akamatsu et al.   NATURE GENETICS

Genome-wide association study in Chinese men identifies two new prostate cancer risk loci at 9q31.2 and 19q13.4

(2012) Jianfeng Xu et al.   NATURE GENETICS

Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits

(2012) Jian Yang et al.   NATURE GENETICS

ChromHMM: automating chromatin-state discovery and characterization

(2012) Jason Ernst et al.   NATURE METHODS

Germline Mutations inHOXB13and Prostate-Cancer Risk

(2012) Charles M. Ewing et al.   NEW ENGLAND JOURNAL OF MEDICINE

Integrative annotation of chromatin elements from ENCODE data

(2012) Michael M. Hoffman et al.   NUCLEIC ACIDS RESEARCH

BRCA2 is a moderate penetrance gene contributing to young-onset prostate cancer: implications for genetic testing in prostate cancer patients

(2011) Z Kote-Jarai et al.   BRITISH JOURNAL OF CANCER

Identification of a novel prostate cancer susceptibility variant in the KLK3 gene transcript

(2011) Z. Kote-Jarai et al.   HUMAN GENETICS

Fine mapping of a region of chromosome 11q13 reveals multiple independent loci associated with risk of prostate cancer

(2011) Charles C. Chung et al.   HUMAN MOLECULAR GENETICS

Gibbs sampling methods for Bayesian quantile regression

(2011) Hideo Kozumi et al.   JOURNAL OF STATISTICAL COMPUTATION AND SIMULATION

Genome-wide association study of prostate cancer in men of African ancestry identifies a susceptibility locus at 17q21

(2011) Christopher A Haiman et al.   NATURE GENETICS

Bayesian model search and multilevel inference for SNP association studies

(2010) Melanie A. Wilson et al.   Annals of Applied Statistics

Bayes and empirical-Bayes multiplicity adjustment in the variable-selection problem

(2010) James G. Scott et al.   ANNALS OF STATISTICS

METAL: fast and efficient meta-analysis of genomewide association scans

(2010) C. J. Willer et al.   BIOINFORMATICS

Genome-wide association study identifies five new susceptibility loci for prostate cancer in the Japanese population

(2010) Ryo Takata et al.   NATURE GENETICS

Data quality control in genetic case-control association studies

(2010) Carl A Anderson et al.   Nature Protocols

The rs10993994 Risk Allele for Prostate Cancer Results in Clinically Relevant Changes in Microseminoprotein-Beta Expression in Tissue and Urine

(2010) Hayley C. Whitaker et al.   PLoS One

A Bayesian Framework to Account for Complex Non-Genetic Factors in Gene Expression Levels Greatly Increases Power in eQTL Studies

(2010) Oliver Stegle et al.   PLoS Computational Biology

Identifying a High Fraction of the Human Genome to be under Selective Constraint Using GERP++

(2010) Eugene V. Davydov et al.   PLoS Computational Biology

Analysis of the 10q11 Cancer Risk Locus Implicates MSMB and NCOA4 in Human Prostate Tumorigenesis

(2010) Mark M. Pomerantz et al.   PLoS Genetics

Candidate Causal Regulatory Effects by Integration of Expression QTLs with Complex Trait Genetic Associations

(2010) Alexandra C. Nica et al.   PLoS Genetics

Identifying novel constrained elements by exploiting biased substitution patterns

(2009) Manuel Garber et al.   BIOINFORMATICS

Bayesian Meta-Analysis of Genetic Association Studies with Different Sets of Markers

(2008) Claudio Verzilli et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Bias-reduced estimators and confidence intervals for odds ratios in genome-wide association studies

(2008) H. Zhong et al.   BIOSTATISTICS

Snagger: A user-friendly program for incorporating additional information for tagSNP selection

(2008) Christopher K Edlund et al.   BMC BIOINFORMATICS

Bayesian variable and model selection methods for genetic association studies

(2008) Brooke L. Fridley   GENETIC EPIDEMIOLOGY

Empirical Bayes vs. fully Bayes variable selection

(2007) Wen Cui et al.   JOURNAL OF STATISTICAL PLANNING AND INFERENCE