Dissection of a Complex Disease Susceptibility Region Using a Bayesian Stochastic Search Approach to Fine Mapping
出版年份 2015 全文链接
标题
Dissection of a Complex Disease Susceptibility Region Using a Bayesian Stochastic Search Approach to Fine Mapping
作者
关键词
T cells, Haplotypes, Variant genotypes, Molecular genetics, Multiple sclerosis, Simulation and modeling, Disease surveillance, Gene mapping
出版物
PLoS Genetics
Volume 11, Issue 6, Pages e1005272
出版商
Public Library of Science (PLoS)
发表日期
2015-06-25
DOI
10.1371/journal.pgen.1005272
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Roadmap for regulation
- (2015) Casey E. Romanoski et al. NATURE
- Regularization Paths for Generalized Linear Models via Coordinate Descent
- (2015) Jerome Friedman et al. Journal of Statistical Software
- Joint Analysis of Functional Genomic Data and Genome-wide Association Studies of 18 Human Traits
- (2014) Joseph K. Pickrell AMERICAN JOURNAL OF HUMAN GENETICS
- Detection and replication of epistasis influencing transcription in humans
- (2014) Gibran Hemani et al. NATURE
- Another explanation for apparent epistasis
- (2014) Andrew R. Wood et al. NATURE
- Intersection of population variation and autoimmunity genetics in human T cell activation
- (2014) C. J. Ye et al. SCIENCE
- Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics
- (2014) Claudia Giambartolomei et al. PLoS Genetics
- Genetic Variants Regulating Immune Cell Levels in Health and Disease
- (2013) Valeria Orrù et al. CELL
- Phosphofructokinase deficiency impairs ATP generation, autophagy, and redox balance in rheumatoid arthritis T cells
- (2013) Zhen Yang et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Postthymic Expansion in Human CD4 Naive T Cells Defined by Expression of Functional High-Affinity IL-2 Receptors
- (2013) M. L. Pekalski et al. JOURNAL OF IMMUNOLOGY
- eRNAs Promote Transcription by Establishing Chromatin Accessibility at Defined Genomic Loci
- (2013) Kambiz Mousavi et al. MOLECULAR CELL
- Genetics of rheumatoid arthritis contributes to biology and drug discovery
- (2013) Yukinori Okada et al. NATURE
- Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis
- (2013) Ashley H Beecham et al. NATURE GENETICS
- Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis
- (2013) Anne Hinks et al. NATURE GENETICS
- Multiple Autoimmune-Associated Variants Confer Decreased IL-2R Signaling in CD4+CD25hi T Cells of Type 1 Diabetic and Multiple Sclerosis Patients
- (2013) Karen Cerosaletti et al. PLoS One
- Integrated Enrichment Analysis of Variants and Pathways in Genome-Wide Association Studies Indicates Central Role for IL-2 Signaling Genes in Type 1 Diabetes, and Cytokine Signaling Genes in Crohn's Disease
- (2013) Peter Carbonetto et al. PLoS Genetics
- GUESS-ing Polygenic Associations with Multiple Phenotypes Using a GPU-Based Evolutionary Stochastic Search Algorithm
- (2013) Leonardo Bottolo et al. PLoS Genetics
- STAR: ultrafast universal RNA-seq aligner
- (2012) Alexander Dobin et al. BIOINFORMATICS
- Type 1 Diabetes-Associated IL2RA Variation Lowers IL-2 Signaling and Contributes to Diminished CD4+CD25+ Regulatory T Cell Function
- (2012) G. Garg et al. JOURNAL OF IMMUNOLOGY
- The accessible chromatin landscape of the human genome
- (2012) Robert E. Thurman et al. NATURE
- High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis
- (2012) Steve Eyre et al. NATURE GENETICS
- Bayesian refinement of association signals for 14 loci in 3 common diseases
- (2012) Julian B Maller et al. NATURE GENETICS
- Bayesian variable selection regression for genome-wide association studies and other large-scale problems
- (2011) Yongtao Guan et al. Annals of Applied Statistics
- Bayesian Detection of Expression Quantitative Trait Loci Hot Spots
- (2011) Leonardo Bottolo et al. GENETICS
- Long-range DNA looping and gene expression analyses identify DEXI as an autoimmune disease candidate gene
- (2011) Lucy J. Davison et al. HUMAN MOLECULAR GENETICS
- Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease
- (2011) Gosia Trynka et al. NATURE GENETICS
- SNP Selection in genome-wide and candidate gene studies via penalized logistic regression
- (2010) Kristin L. Ayers et al. GENETIC EPIDEMIOLOGY
- Interleukin-2 Receptor Signaling: At the Interface between Tolerance and Immunity
- (2010) Thomas R. Malek et al. IMMUNITY
- Reduced Expression of IFIH1 Is Protective for Type 1 Diabetes
- (2010) Kate Downes et al. PLoS One
- Genome-wide association analysis by lasso penalized logistic regression
- (2009) Tong Tong Wu et al. BIOINFORMATICS
- The Sequence Alignment/Map format and SAMtools
- (2009) H. Li et al. BIOINFORMATICS
- Cell-specific protein phenotypes for the autoimmune locus IL2RA using a genotype-selectable human bioresource
- (2009) Calliope A Dendrou et al. NATURE GENETICS
- IL2RA Genetic Heterogeneity in Multiple Sclerosis and Type 1 Diabetes Susceptibility and Soluble Interleukin-2 Receptor Production
- (2009) Lisa M. Maier et al. PLoS Genetics
- A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies
- (2009) Bryan N. Howie et al. PLoS Genetics
- A role for PFK-2/FBPase-2, as distinct from fructose 2,6-bisphosphate, in regulation of insulin secretion in pancreatic β-cells
- (2008) Catherine Arden et al. BIOCHEMICAL JOURNAL
- Genome-wide association studies: potential next steps on a genetic journey
- (2008) M. I. McCarthy et al. HUMAN MOLECULAR GENETICS
- The IL-2/CD25 Pathway Determines Susceptibility to T1D in Humans and NOD Mice
- (2008) Calliope A. Dendrou et al. JOURNAL OF CLINICAL IMMUNOLOGY
- Rheumatoid arthritis susceptibility loci at chromosomes 10p15, 12q13 and 22q13
- (2008) Anne Barton et al. NATURE GENETICS
- Simultaneous Analysis of All SNPs in Genome-Wide and Re-Sequencing Association Studies
- (2008) Clive J. Hoggart et al. PLoS Genetics
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now