Dynamic allocation of orthogonal ribosomes facilitates uncoupling of co-expressed genes

Programming mRNA decay to modulate synthetic circuit resource allocation

(2017) Ophelia S. Venturelli et al.   Nature Communications

Decoupling Resource-Coupled Gene Expression in Living Cells

(2017) Tatenda Shopera et al.   ACS Synthetic Biology

Resource Competition Shapes the Response of Genetic Circuits

(2017) Yili Qian et al.   ACS Synthetic Biology

Orthogonal Ribosome Biofirewall

(2017) Bin Jia et al.   ACS Synthetic Biology

Advances in Chromobacterium violaceum and properties of violacein-Its main secondary metabolite: A review

(2016) Nelson Durán et al.   BIOTECHNOLOGY ADVANCES

A Minimal Model of Ribosome Allocation Dynamics Captures Trade-offs in Expression between Endogenous and Synthetic Genes

(2016) Thomas E. Gorochowski et al.   ACS Synthetic Biology

Isocost Lines Describe the Cellular Economy of Genetic Circuits

(2015) Andras Gyorgy et al.   BIOPHYSICAL JOURNAL

Repurposing the translation apparatus for synthetic biology

(2015) Benjamin J Des Soye et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Protein synthesis by ribosomes with tethered subunits

(2015) Cédric Orelle et al.   NATURE

Quantifying cellular capacity identifies gene expression designs with reduced burden

(2015) Francesca Ceroni et al.   NATURE METHODS

Engineered ribosomal RNA operon copy-number variants of E. coli reveal the evolutionary trade-offs shaping rRNA operon number

(2015) Zsuzsanna Gyorfy et al.   NUCLEIC ACIDS RESEARCH

Dealing with the genetic load in bacterial synthetic biology circuits: convergences with the Ohm's law

(2015) M. Carbonell-Ballestero et al.   NUCLEIC ACIDS RESEARCH

Mechanistic links between cellular trade-offs, gene expression, and growth

(2015) Andrea Y. Weiße et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A portable expression resource for engineering cross-species genetic circuits and pathways

(2015) Manish Kushwaha et al.   Nature Communications

Concerted, Rapid, Quantitative, and Site-Specific Dual Labeling of Proteins

(2014) Amit Sachdeva et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A 'resource allocator' for transcription based on a highly fragmented T7 RNA polymerase

(2014) T. H. Segall-Shapiro et al.   Molecular Systems Biology

Tunable protein degradation in bacteria

(2014) D Ewen Cameron et al.   NATURE BIOTECHNOLOGY

Principles of genetic circuit design

(2014) Jennifer A N Brophy et al.   NATURE METHODS

Tuning the dials of Synthetic Biology

(2013) J. A. J. Arpino et al.   MICROBIOLOGY-SGM

Translation rate is controlled by coupled trade-offs between site accessibility, selective RNA unfolding and sliding at upstream standby sites

(2013) Amin Espah Borujeni et al.   NUCLEIC ACIDS RESEARCH

Contextualizing context for synthetic biology - identifying causes of failure of synthetic biological systems

(2012) Stefano Cardinale et al.   Biotechnology Journal

The Standard European Vector Architecture (SEVA): a coherent platform for the analysis and deployment of complex prokaryotic phenotypes

(2012) Rafael Silva-Rocha et al.   NUCLEIC ACIDS RESEARCH

Cost of Unneeded Proteins in E. coli Is Reduced after Several Generations in Exponential Growth

(2010) Irit Shachrai et al.   MOLECULAR CELL

Interdependence of Cell Growth and Gene Expression: Origins and Consequences

(2010) M. Scott et al.   SCIENCE

Emergent bistability by a growth-modulating positive feedback circuit

(2009) Cheemeng Tan et al.   Nature Chemical Biology

Enzymatic assembly of DNA molecules up to several hundred kilobases

(2009) Daniel G Gibson et al.   NATURE METHODS

(p)ppGpp: Still Magical?

(2008) Katarzyna Potrykus et al.   Annual Review of Microbiology

Computational design of orthogonal ribosomes

(2008) Lon M. Chubiz et al.   NUCLEIC ACIDS RESEARCH