Endothelial deletion of Ino80 disrupts coronary angiogenesis and causes congenital heart disease

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The Sinocyclocheilus cavefish genome provides insights into cave adaptation

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Novel functions for the transcription factor E2F4 in development and disease

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(2016) Hui Zhang et al.   CIRCULATION RESEARCH

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(2016) Gaetano D'Amato et al.   FEBS Journal

INO80 governs superenhancer-mediated oncogenic transcription and tumor growth in melanoma

(2016) Bingying Zhou et al.   GENES & DEVELOPMENT

The INO80 Complex Requires the Arp5-Ies6 Subcomplex for Chromatin Remodeling and Metabolic Regulation

(2016) Wei Yao et al.   MOLECULAR AND CELLULAR BIOLOGY

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(2016) Shahin Rafii et al.   NATURE

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Endocardial Notch Signaling in Cardiac Development and Disease

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The Ino80 complex prevents invasion of euchromatin into silent chromatin

(2015) Yong Xue et al.   GENES & DEVELOPMENT

Left ventricular non-compaction cardiomyopathy

(2015) Jeffrey A Towbin et al.   LANCET

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(2015) Anshul Kundaje et al.   NATURE

Sequential Notch activation regulates ventricular chamber development

(2015) Gaetano D’Amato et al.   NATURE CELL BIOLOGY

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Whole Exome Sequencing Implicates an INO80D Mutation in a Syndrome of Aortic Hypoplasia, Premature Atherosclerosis, and Arterial Stiffness

(2014) K. Shameer et al.   Circulation-Cardiovascular Genetics

The sinus venosus contributes to coronary vasculature through VEGFC-stimulated angiogenesis

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VEGF-C and aortic cardiomyocytes guide coronary artery stem development

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INO80 and SWR complexes: relating structure to function in chromatin remodeling

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Molecular mechanism of ventricular trabeculation/compaction and the pathogenesis of the left ventricular noncompaction cardiomyopathy (LVNC)

(2013) Wenjun Zhang et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS

Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes

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De novo mutations in histone-modifying genes in congenital heart disease

(2013) Samir Zaidi et al.   NATURE

Mutations in the NOTCH pathway regulator MIB1 cause left ventricular noncompaction cardiomyopathy

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The chromatin remodeller CHD8 is required for E2F-dependent transcription activation of S-phase genes

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(2013) Michael Lawrence et al.   PLoS Computational Biology

Endocardial Cells Form the Coronary Arteries by Angiogenesis through Myocardial-Endocardial VEGF Signaling

(2012) Bingruo Wu et al.   CELL

The INO80 chromatin remodeling complex prevents polyploidy and maintains normal chromatin structure at centromeres

(2012) A. L. Chambers et al.   GENES & DEVELOPMENT

Cozzarelli Prize Winner: Robust cardiomyocyte differentiation from human pluripotent stem cells via temporal modulation of canonical Wnt signaling

(2012) X. Lian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

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A genome-wide RNAi screen reveals determinants of human embryonic stem cell identity

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Coronary arteries form by developmental reprogramming of venous cells

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Mutation of p107 exacerbates the consequences of Rb loss in embryonic tissues and causes cardiac and blood vessel defects

(2009) S. D. Berman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ino80 Chromatin Remodeling Complex Promotes Recovery of Stalled Replication Forks

(2008) Kenji Shimada et al.   CURRENT BIOLOGY

Prox1 maintains muscle structure and growth in the developing heart

(2008) C. A. Risebro et al.   DEVELOPMENT

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(2008) Yong Zhang et al.   GENOME BIOLOGY