USP49 participates in the DNA damage response by forming a positive feedback loop with p53

USP7 promotes cell proliferation through the stabilization of Ki-67 protein in non-small cell lung cancer cells

(2016) Chao Zhang et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Stabilization of histone demethylase PHF8 by USP7 promotes breast carcinogenesis

(2016) Qian Wang et al.   JOURNAL OF CLINICAL INVESTIGATION

HAUSP deubiquitinates and stabilizes N-Myc in neuroblastoma

(2016) Omid Tavana et al.   NATURE MEDICINE

Expression of USP7 and MARCH7 Is Correlated with Poor Prognosis in Epithelial Ovarian Cancer

(2016) Li Zhang et al.   TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE

Mechanisms of p53 degradation

(2015) Chuck C.-K. Chao   CLINICA CHIMICA ACTA

Deubiquitinases (DUBs) and DUB inhibitors: a patent review

(2015) Pershang Farshi et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

FoxO6 inhibits cell proliferation in lung carcinoma through up-regulation of USP7

(2015) HONG-JUN HU et al.   Molecular Medicine Reports

Usp5 links suppression of p53 and FAS levels in melanoma to the BRAF pathway

(2015) Harish Potu et al.   Oncotarget

MG132, a proteasome inhibitor, enhances LDL uptake in HepG2 cells in vitro by regulating LDLR and PCSK9 expression

(2014) Hong Yan et al.   ACTA PHARMACOLOGICA SINICA

Nemo-like kinase is critical for p53 stabilization and function in response to DNA damage

(2014) H-H Zhang et al.   CELL DEATH AND DIFFERENTIATION

USP7 overexpression predicts a poor prognosis in lung squamous cell carcinoma and large cell carcinoma

(2014) Guang-Yin Zhao et al.   TUMOR BIOLOGY

Metformin Inhibits Esophagus Cancer Proliferation through Upregulation of USP7

(2013) Yunhua Xu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

USP49 deubiquitinates histone H2B and regulates cotranscriptional pre-mRNA splicing

(2013) Z. Zhang et al.   GENES & DEVELOPMENT

Expression of HAUSP in gliomas correlates with disease progression and survival of patients

(2013) CHUANDONG CHENG et al.   ONCOLOGY REPORTS

The MDM2–p53 pathway: multiple roles in kidney development

(2013) Samir S. El-Dahr et al.   PEDIATRIC NEPHROLOGY

USP7 inhibitor P22077 inhibits neuroblastoma growth via inducing p53-mediated apoptosis

(2013) Y-H Fan et al.   Cell Death & Disease

STAT3 repressed USP7 expression is crucial for colon cancer development

(2012) Yang Zhi et al.   FEBS LETTERS

The DNA damage response and cancer therapy

(2012) Christopher J. Lord et al.   NATURE

Atypical ubiquitylation — the unexplored world of polyubiquitin beyond Lys48 and Lys63 linkages

(2012) Yogesh Kulathu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Distinct p53 Transcriptional Programs Dictate Acute DNA-Damage Responses and Tumor Suppression

(2011) Colleen A. Brady et al.   CELL

The Multifaceted Roles of USP7: New Therapeutic Opportunities

(2011) Benjamin Nicholson et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

USP4 inhibits p53 through deubiquitinating and stabilizing ARF-BP1

(2011) Xinna Zhang et al.   EMBO JOURNAL

USP10 Regulates p53 Localization and Stability by Deubiquitinating p53

(2010) Jian Yuan et al.   CELL

MG132, a proteasome inhibitor-induced calf pulmonary arterial endothelial cell growth and death, are changed by MAPK inhibitors

(2010) Bo Ra You et al.   DRUG AND CHEMICAL TOXICOLOGY

The regulation of energy metabolism and the IGF-1/mTOR pathways by the p53 protein

(2010) Zhaohui Feng et al.   TRENDS IN CELL BIOLOGY

Blinded by the Light: The Growing Complexity of p53

(2009) Karen H. Vousden et al.   CELL

Lysine 63 Polyubiquitination in Immunotherapy and in Cancer-promoting Inflammation

(2009) I. Martinez-Forero et al.   CLINICAL CANCER RESEARCH

The deubiquitinylation and localization of PTEN are regulated by a HAUSP–PML network

(2008) Min Sup Song et al.   NATURE