PGC1α promotes cholangiocarcinoma metastasis by upregulating PDHA1 and MPC1 expression to reverse the Warburg effect

A PGC1α-mediated transcriptional axis suppresses melanoma metastasis

(2016) Chi Luo et al.   NATURE

The metabolic co-regulator PGC1α suppresses prostate cancer metastasis

(2016) Veronica Torrano et al.   NATURE CELL BIOLOGY

The Warburg effect in tumor progression: Mitochondrial oxidative metabolism as an anti-metastasis mechanism

(2015) Jianrong Lu et al.   CANCER LETTERS

Differences in Metabolic Programming Define the Site of Breast Cancer Cell Metastasis

(2015) Heike Döppler et al.   Cell Metabolism

Redox Homeostasis and Mitochondrial Dynamics

(2015) Peter H.G.M. Willems et al.   Cell Metabolism

New insights into PGC-1 coactivators: redefining their role in the regulation of mitochondrial function and beyond

(2015) Josep A. Villena   FEBS Journal

Metabolism in cancer metastasis

(2015) Georg F. Weber   INTERNATIONAL JOURNAL OF CANCER

Oxidative stress inhibits distant metastasis by human melanoma cells

(2015) Elena Piskounova et al.   NATURE

Targeting mitochondria metabolism for cancer therapy

(2015) Samuel E Weinberg et al.   Nature Chemical Biology

PI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasion

(2015) M. Cecilia Caino et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dysregulated metabolism contributes to oncogenesis

(2015) Matthew D. Hirschey et al.   SEMINARS IN CANCER BIOLOGY

Suppression of PGC-1α Is Critical for Reprogramming Oxidative Metabolism in Renal Cell Carcinoma

(2015) Edward L. LaGory et al.   Cell Reports

Reciprocal activation between ATPase inhibitory factor 1 and NF-κB drives hepatocellular carcinoma angiogenesis and metastasis

(2014) Ruipeng Song et al.   HEPATOLOGY

Cholangiocarcinoma

(2014) Nataliya Razumilava et al.   LANCET

PGC-1α mediates mitochondrial biogenesis and oxidative phosphorylation in cancer cells to promote metastasis

(2014) Valerie S. LeBleu et al.   NATURE CELL BIOLOGY

PGC1α Expression Defines a Subset of Human Melanoma Tumors with Increased Mitochondrial Capacity and Resistance to Oxidative Stress

(2013) Francisca Vazquez et al.   CANCER CELL

Oncogenic BRAF Regulates Oxidative Metabolism via PGC1α and MITF

(2013) Rizwan Haq et al.   CANCER CELL

Metastasis Suppressor KISS1 Seems to Reverse the Warburg Effect by Enhancing Mitochondrial Biogenesis

(2013) W. Liu et al.   CANCER RESEARCH

Pathogenesis, Diagnosis, and Management of Cholangiocarcinoma

(2013) Sumera Rizvi et al.   GASTROENTEROLOGY

Mitochondrial Dynamics — Mitochondrial Fission and Fusion in Human Diseases

(2013) Stephen L. Archer   NEW ENGLAND JOURNAL OF MEDICINE

Androgens regulate prostate cancer cell growth via an AMPK-PGC-1α-mediated metabolic switch

(2013) J B Tennakoon et al.   ONCOGENE

Pyruvate uptake is increased in highly invasive ovarian cancer cells under anoikis conditions for anaplerosis, mitochondrial function, and migration

(2012) Christine A. Caneba et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Links between metabolism and cancer

(2012) C. V. Dang   GENES & DEVELOPMENT

Guidelines for the diagnosis and treatment of cholangiocarcinoma: an update

(2012) Shahid A Khan et al.   GUT

Fusion and Fission: Interlinked Processes Critical for Mitochondrial Health

(2011) David C. Chan   Annual Review of Genetics

PGC1  Promotes Tumor Growth by Inducing Gene Expression Programs Supporting Lipogenesis

(2011) K. Bhalla et al.   CANCER RESEARCH

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

Tumor Cell Metabolism: Cancer's Achilles' Heel

(2008) Guido Kroemer et al.   CANCER CELL