Engineered Janus probes modulate nucleic acid amplification to expand the dynamic range for direct detection of viral genomes in one microliter crude serum samples

Simple multiplexed PCR-based barcoding of DNA for ultrasensitive mutation detection by next-generation sequencing

(2017) Anders Ståhlberg et al.   Nature Protocols

Single copy-sensitive electrochemical assay for circulating methylated DNA in clinical samples with ultrahigh specificity based on a sequential discrimination–amplification strategy

(2017) Xuyao Wang et al.   Chemical Science

Quenching of Unincorporated Amplification Signal Reporters in Reverse-Transcription Loop-Mediated Isothermal Amplification Enabling Bright, Single-Step, Closed-Tube, and Multiplexed Detection of RNA Viruses

(2016) Cameron S. Ball et al.   ANALYTICAL CHEMISTRY

Virtual microfluidics for digital quantification and single-cell sequencing

(2016) Liyi Xu et al.   NATURE METHODS

Simple, multiplexed, PCR-based barcoding of DNA enables sensitive mutation detection in liquid biopsies using sequencing

(2016) Anders Ståhlberg et al.   NUCLEIC ACIDS RESEARCH

Ultrasensitive detection of telomerase activity in a single cell using stem-loop primer-mediated exponential amplification (SPEA) with near zero nonspecific signal

(2016) Honghong Wang et al.   Chemical Science

Inhibitory Impact of 3′-Terminal 2′-O-Methylated Small Silencing RNA on Target-Primed Polymerization and Unbiased Amplified Quantification of the RNA in Arabidopsis thaliana

(2015) Feng Chen et al.   ANALYTICAL CHEMISTRY

Mismatch Extension of DNA Polymerases and High-Accuracy Single Nucleotide Polymorphism Diagnostics by Gold Nanoparticle-Improved Isothermal Amplification

(2015) Feng Chen et al.   ANALYTICAL CHEMISTRY

Mixed-Dye-Based Label-Free and Sensitive Dual Fluorescence for the Product Detection of Nucleic Acid Isothermal Multiple-Self-Matching-Initiated Amplification

(2015) Xiong Ding et al.   ANALYTICAL CHEMISTRY

Robust Strand Exchange Reactions for the Sequence-Specific, Real-Time Detection of Nucleic Acid Amplicons

(2015) Yu Sherry Jiang et al.   ANALYTICAL CHEMISTRY

A Rapid, Amplification-Free, and Sensitive Diagnostic Assay for Single-Step Multiplexed Fluorescence Detection of MicroRNA

(2015) Zongwen Jin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Isothermal Amplification of Nucleic Acids

(2015) Yongxi Zhao et al.   CHEMICAL REVIEWS

Two Methods for Increased Specificity and Sensitivity in Loop-Mediated Isothermal Amplification

(2015) De-Guo Wang et al.   MOLECULES

Multiplexed locus-specific analysis of DNA methylation in single cells

(2015) Lih Feng Cheow et al.   Nature Protocols

Genome-wide profiling of in vivo RNA structure at single-nucleotide resolution using structure-seq

(2015) Yiliang Ding et al.   Nature Protocols

Isothermal Nucleic Acid Amplification Strategy by Cyclic Enzymatic Repairing for Highly Sensitive MicroRNA Detection

(2014) Dian-Ming Zhou et al.   ANALYTICAL CHEMISTRY

Measuring Fate and Rate of Single-Molecule Competition of Amplification and Restriction Digestion, and Its Use for Rapid Genotyping Tested with Hepatitis C Viral RNA

(2014) Bing Sun et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enhancing-effect of gold nanoparticles on DNA strand displacement amplifications and their application to an isothermal telomerase assay

(2014) Leilei Tian et al.   Chemical Science

Lab in a Tube: Ultrasensitive Detection of MicroRNAs at the Single-Cell Level and in Breast Cancer Patients Using Quadratic Isothermal Amplification

(2013) Ruixue Duan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Genome-Wide Detection of Single-Nucleotide and Copy-Number Variations of a Single Human Cell

(2012) C. Zong et al.   SCIENCE

Significance of HBV DNA levels at 12 weeks of telbivudine treatment and the 3 years treatment outcome

(2010) Wai-Kay Seto et al.   JOURNAL OF HEPATOLOGY

Specific versus Nonspecific Isothermal DNA Amplification through Thermophilic Polymerase and Nicking Enzyme Activities†

(2008) Eric Tan et al.   BIOCHEMISTRY

Loop-mediated isothermal amplification (LAMP) of gene sequences and simple visual detection of products

(2008) Norihiro Tomita et al.   Nature Protocols