Reduced peripheral availability of tryptophan and increased activation of the kynurenine pathway and cortisol correlate with major depression and suicide

Kynurenine pathway metabolites and suicidality

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Tryptophan via serotonin/kynurenine pathways abnormalities in a large cohort of aggressive inmates: markers for aggression

(2016) Stefano Comai et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Cortisol levels and suicidal behavior: A meta-analysis

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An enzyme in the kynurenine pathway that governs vulnerability to suicidal behavior by regulating excitotoxicity and neuroinflammation

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Monoamine oxidase a gene promoter methylation and transcriptional downregulation in an offender population with antisocial personality disorder

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Etiological classification of depression based on the enzymes of tryptophan metabolism

(2014) Katsuhiko Fukuda   BMC Psychiatry

PlasmaL-Tryptophan Concentration in Major Depressive Disorder

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Positron Emission Tomography Quantification of Serotonin Transporter in Suicide Attempters with Major Depressive Disorder

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The serotonergic system in mood disorders and suicidal behaviour

(2013) J. J. Mann   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Network beyond IDO in psychiatric disorders: Revisiting neurodegeneration hypothesis

(2013) Aye-Mu Myint et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Kynurenines in the mammalian brain: when physiology meets pathology

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Cortisol and depression: three questions for psychiatry

(2012) J. Herbert   PSYCHOLOGICAL MEDICINE

Association of the MAOA promoter uVNTR polymorphism with suicide attempts in patients with major depressive disorder

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Plasma kynurenine levels are elevated in suicide attempters with major depressive disorder

(2011) M. Elizabeth Sublette et al.   BRAIN BEHAVIOR AND IMMUNITY

The possible role of the kynurenine pathway in anhedonia in adolescents

(2011) Vilma Gabbay et al.   JOURNAL OF NEURAL TRANSMISSION

The possible role of the kynurenine pathway in adolescent depression with melancholic features

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Effects of PEG-interferon alpha plus ribavirin on tryptophan metabolism in patients with chronic hepatitis C

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The new ‘5-HT’ hypothesis of depression: Cell-mediated immune activation induces indoleamine 2,3-dioxygenase, which leads to lower plasma tryptophan and an increased synthesis of detrimental tryptophan catabolites (TRYCATs), both of which contribute to the onset of depression

(2010) M. Maes et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY