An enzyme in the kynurenine pathway that governs vulnerability to suicidal behavior by regulating excitotoxicity and neuroinflammation

Meta-Analysis of Cytokines and Chemokines in Suicidality: Distinguishing Suicidal Versus Nonsuicidal Patients

(2015) Carmen Black et al.   BIOLOGICAL PSYCHIATRY

A role for inflammatory metabolites as modulators of the glutamate N-methyl-d-aspartate receptor in depression and suicidality

(2015) Cecilie Bay-Richter et al.   BRAIN BEHAVIOR AND IMMUNITY

Possible involvement of corticosterone and serotonin in antidepressant and antianxiety effects of chromium picolinate in chronic unpredictable mild stress induced depression and anxiety in rats

(2015) Vivek Kumar Dubey et al.   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

Expression of the Kynurenine Pathway in Human Peripheral Blood Mononuclear Cells: Implications for Inflammatory and Neurodegenerative Disease

(2015) Simon P. Jones et al.   PLoS One

EFFECTS OF KETAMINE ON EXPLICIT AND IMPLICIT SUICIDAL COGNITION: A RANDOMIZED CONTROLLED TRIAL IN TREATMENT-RESISTANT DEPRESSION

(2014) Rebecca B. Price et al.   DEPRESSION AND ANXIETY

Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease

(2014) Mike A Nalls et al.   NATURE GENETICS

The Kynurenine Pathway of Tryptophan Degradation is Activated During Osteoblastogenesis

(2014) Christopher Vidal et al.   STEM CELLS

SUICIDAL IDEATION IS ASSOCIATED WITH ELEVATED INFLAMMATION IN PATIENTS WITH MAJOR DEPRESSIVE DISORDER

(2013) Aoife O'Donovan et al.   DEPRESSION AND ANXIETY

The role of inflammatory cytokines in suicidal behavior: A systematic review

(2013) Gianluca Serafini et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Decreased cerebrospinal fluid secretogranin II concentrations in severe forms of bipolar disorder

(2013) Joel Jakobsson et al.   JOURNAL OF PSYCHIATRY & NEUROSCIENCE

Connecting inflammation with glutamate agonism in suicidality

(2013) Sophie Erhardt et al.   NEUROPSYCHOPHARMACOLOGY

Conceptual Confluence: The Kynurenine Pathway as a Common Target for Ketamine and the Convergence of the Inflammation and Glutamate Hypotheses of Depression

(2013) Andrew H Miller   NEUROPSYCHOPHARMACOLOGY

NMDA Receptor Blockade by Ketamine Abrogates Lipopolysaccharide-Induced Depressive-Like Behavior in C57BL/6J Mice

(2013) Adam K Walker et al.   NEUROPSYCHOPHARMACOLOGY

Quinolinic acid, the inescapable neurotoxin

(2012) Gilles J. Guillemin   FEBS Journal

Kynurenines in the mammalian brain: when physiology meets pathology

(2012) Robert Schwarcz et al.   NATURE REVIEWS NEUROSCIENCE

Plasma kynurenine levels are elevated in suicide attempters with major depressive disorder

(2011) M. Elizabeth Sublette et al.   BRAIN BEHAVIOR AND IMMUNITY

Severe depression is associated with increased microglial quinolinic acid in subregions of the anterior cingulate gyrus: Evidence for an immune-modulated glutamatergic neurotransmission?

(2011) Johann Steiner et al.   Journal of Neuroinflammation

Cytokine levels in the blood may distinguish suicide attempters from depressed patients

(2010) Shorena Janelidze et al.   BRAIN BEHAVIOR AND IMMUNITY

Rapid Resolution of Suicidal Ideation After a Single Infusion of anN-Methyl-D-Aspartate Antagonist in Patients With Treatment-Resistant Major Depressive Disorder

(2010) Nancy DiazGranados et al.   JOURNAL OF CLINICAL PSYCHIATRY

Interleukin-6 Is Elevated in the Cerebrospinal Fluid of Suicide Attempters and Related to Symptom Severity

(2009) Daniel Lindqvist et al.   BIOLOGICAL PSYCHIATRY

The crystal structure of human α-amino-β-carboxymuconate-ε-semialdehyde decarboxylase in complex with 1,3-dihydroxyacetonephosphate suggests a regulatory link between NAD synthesis and glycolysis

(2009) Silvia Garavaglia et al.   FEBS Journal

Immunological aspects in the neurobiology of suicide: Elevated microglial density in schizophrenia and depression is associated with suicide

(2006) Johann Steiner et al.   JOURNAL OF PSYCHIATRIC RESEARCH