Natural noncanonical protein splicing yields products with diverse β-amino acid residues

Mechanistic elucidation of the mycofactocin-biosynthetic radicalS-adenosylmethionine protein, MftC

(2017) Bulat Khaliullin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An Orthogonal D2O-Based Induction System that Provides Insights intod-Amino Acid Pattern Formation by Radical S-Adenosylmethionine Peptide Epimerases

(2016) Brandon I. Morinaka et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent Developments in General Methodologies for the Synthesis of α-Ketoamides

(2016) Carmela De Risi et al.   CHEMICAL REVIEWS

Jamaicensamide A, a Peptide Containing β-Amino-α-keto and Thiazole-Homologated η-Amino Acid Residues from the Sponge Plakina jamaicensis

(2016) Matthew T. Jamison et al.   JOURNAL OF NATURAL PRODUCTS

In Vivo Biosynthesis of a β-Amino Acid-Containing Protein

(2016) Clarissa Melo Czekster et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ribosomal Synthesis of Peptides with Multiple β-Amino Acids

(2016) Tomoshige Fujino et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Seven enzymes create extraordinary molecular complexity in an uncultivated bacterium

(2016) Michael F. Freeman et al.   Nature Chemistry

Protein Synthesis with Ribosomes Selected for the Incorporation of β-Amino Acids

(2015) Rumit Maini et al.   BIOCHEMISTRY

PqqD Is a Novel Peptide Chaperone That Forms a Ternary Complex with the RadicalS-Adenosylmethionine Protein PqqE in the Pyrroloquinoline Quinone Biosynthetic Pathway

(2015) John A. Latham et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biosynthetic Versatility and Coordinated Action of 5′-Deoxyadenosyl Radicals in Deazaflavin Biosynthesis

(2015) Benjamin Philmus et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A prevalent peptide-binding domain guides ribosomal natural product biosynthesis

(2015) Brandon J Burkhart et al.   Nature Chemical Biology

The Phyre2 web portal for protein modeling, prediction and analysis

(2015) Lawrence A Kelley et al.   Nature Protocols

Structure and function of the global ocean microbiome

(2015) S. Sunagawa et al.   SCIENCE

RadicalS-Adenosyl Methionine Epimerases: Regioselective Introduction of DiverseD-Amino Acid Patterns into Peptide Natural Products

(2014) Brandon I. Morinaka et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Expanding and Reprogramming the Genetic Code of Cells and Animals

(2014) Jason W. Chin   Annual Review of Biochemistry

SPASM and Twitch Domains inS-Adenosylmethionine (SAM) Radical Enzymes

(2014) Tsehai A. J. Grell et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biosynthesis of natural products containing β-amino acids

(2014) Fumitaka Kudo et al.   NATURAL PRODUCT REPORTS

Calyculin biogenesis from a pyrophosphate protoxin produced by a sponge symbiont

(2014) Toshiyuki Wakimoto et al.   Nature Chemical Biology

Deciphering key features in protein structures with the new ENDscript server

(2014) Xavier Robert et al.   NUCLEIC ACIDS RESEARCH

The HydG Enzyme Generates an Fe(CO)2(CN) Synthon in Assembly of the FeFe Hydrogenase H-Cluster

(2014) J. M. Kuchenreuther et al.   SCIENCE

Incorporation of β-amino acids into dihydrofolate reductase by ribosomes having modifications in the peptidyltransferase center

(2013) Rumit Maini et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Structural Characterization of Four Prochlorosins: A Novel Class of Lantipeptides Produced by Planktonic Marine Cyanobacteria

(2012) Weixin Tang et al.   BIOCHEMISTRY

Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature

(2012) Paul G. Arnison et al.   NATURAL PRODUCT REPORTS

Metagenome Mining Reveals Polytheonamides as Posttranslationally Modified Ribosomal Peptides

(2012) M. F. Freeman et al.   SCIENCE

Myxoprincomide: A Natural Product from Myxococcus xanthus Discovered by Comprehensive Analysis of the Secondary Metabolome

(2011) Niña Socorro Cortina et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Characterization of NocL Involved in Thiopeptide Nocathiacin I Biosynthesis

(2011) Qi Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Radical-mediated enzymatic carbon chain fragmentation-recombination

(2011) Qi Zhang et al.   Nature Chemical Biology

Expansion of ribosomally produced natural products: a nitrile hydratase- and Nif11-related precursor family

(2010) Daniel H Haft et al.   BMC BIOLOGY

Solution Structure of Polytheonamide B, a Highly Cytotoxic Nonribosomal Polypeptide from Marine Sponge

(2010) Toshiyuki Hamada et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Xanthomonas campestrisPqqD in the pyrroloquinoline quinone biosynthesis operon adopts a novel saddle-like fold that possibly serves as a PQQ carrier

(2009) Tung-Yi Tsai et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS