Chemoproteomics reveals baicalin activates hepatic CPT1 to ameliorate diet-induced obesity and hepatic steatosis
出版年份 2018 全文链接
标题
Chemoproteomics reveals baicalin activates hepatic CPT1 to ameliorate diet-induced obesity and hepatic steatosis
作者
关键词
-
出版物
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 115, Issue 26, Pages E5896-E5905
出版商
Proceedings of the National Academy of Sciences
发表日期
2018-06-12
DOI
10.1073/pnas.1801745115
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Effect of baicalin on GLUT4 expression and glucose uptake in myotubes of rats
- (2018) Penghua Fang et al. LIFE SCIENCES
- Label-Free Digital Quantification of Lipid Droplets in Single Cells by Stimulated Raman Microscopy on a Microfluidic Platform
- (2016) Chen Cao et al. ANALYTICAL CHEMISTRY
- Photo-induced coupling reactions of tetrazoles with carboxylic acids in aqueous solution: application in protein labelling
- (2016) Shan Zhao et al. CHEMICAL COMMUNICATIONS
- Oral pharmacokinetics of baicalin, wogonoside, oroxylin A 7- O -β- d -glucuronide and their aglycones from an aqueous extract of Scutellariae Radix in the rat
- (2016) Yu Cai et al. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
- Antibacterial Flavonoids from Medicinal Plants Covalently Inactivate Type III Protein Secretion Substrates
- (2016) Lun K. Tsou et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Obesity in IBD: epidemiology, pathogenesis, disease course and treatment outcomes
- (2016) Siddharth Singh et al. Nature Reviews Gastroenterology & Hepatology
- Treatment of Obesity with Celastrol
- (2015) Junli Liu et al. CELL
- The Hunger Genes: Pathways to Obesity
- (2015) Agatha A. van der Klaauw et al. CELL
- Baicalin Attenuates High Fat Diet-Induced Obesity and Liver Dysfunction: Dose-Response and Potential Role of CaMKKβ/AMPK/ACC Pathway
- (2015) Youli Xi et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Mapping sites of aspirin-induced acetylations in live cells by quantitative acid-cleavable activity-based protein profiling (QA-ABPP)
- (2015) Jigang Wang et al. Scientific Reports
- Enzyme Inhibitor Discovery by Activity-Based Protein Profiling
- (2014) Micah J. Niphakis et al. Annual Review of Biochemistry
- Luteolin Attenuates Hepatic Steatosis and Insulin Resistance Through the Interplay Between the Liver and Adipose Tissue in Mice with Diet-Induced Obesity
- (2014) Eun-Young Kwon et al. DIABETES
- The cellular thermal shift assay for evaluating drug target interactions in cells
- (2014) Rozbeh Jafari et al. Nature Protocols
- The pathophysiology of hypertension in patients with obesity
- (2014) Vincent G. DeMarco et al. Nature Reviews Endocrinology
- The hereditary spastic paraplegia-related enzyme DDHD2 is a principal brain triglyceride lipase
- (2014) J. M. Inloes et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Origins and Drivers of Insulin Resistance
- (2013) Andrew M.F. Johnson et al. CELL
- Proteome-wide mapping of cholesterol-interacting proteins in mammalian cells
- (2013) Jonathan J Hulce et al. NATURE METHODS
- NAFLD, NASH and liver cancer
- (2013) Gregory A. Michelotti et al. Nature Reviews Gastroenterology & Hepatology
- Phenotyping the effect of diet on non-alcoholic fatty liver disease
- (2012) Nicole J.W. de Wit et al. JOURNAL OF HEPATOLOGY
- Naringenin prevents cholesterol-induced systemic inflammation, metabolic dysregulation, and atherosclerosis inLdlr−/−mice
- (2012) Julia M. Assini et al. JOURNAL OF LIPID RESEARCH
- Naringin ameliorates metabolic syndrome by activating AMP-activated protein kinase in mice fed a high-fat diet
- (2011) Peng Pu et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- AMPK Phosphorylates and Inhibits SREBP Activity to Attenuate Hepatic Steatosis and Atherosclerosis in Diet-Induced Insulin-Resistant Mice
- (2011) Yu Li et al. Cell Metabolism
- Nobiletin Attenuates VLDL Overproduction, Dyslipidemia, and Atherosclerosis in Mice With Diet-Induced Insulin Resistance
- (2011) E. E. Mulvihill et al. DIABETES
- The PPARβ/δ Activator GW501516 Prevents the Down-Regulation of AMPK Caused by a High-Fat Diet in Liver and Amplifies the PGC-1α-Lipin 1-PPARα Pathway Leading to Increased Fatty Acid Oxidation
- (2011) Emma Barroso et al. ENDOCRINOLOGY
- Enhancing liver mitochondrial fatty acid oxidation capacity in obese mice improves insulin sensitivity independently of hepatic steatosis
- (2011) Julia Monsénégo et al. JOURNAL OF HEPATOLOGY
- Global profiling of dynamic protein palmitoylation
- (2011) Brent R Martin et al. NATURE METHODS
- Long-term baicalin administration ameliorates metabolic disorders and hepatic steatosis in rats given a high-fat diet
- (2009) Hong-xia Guo et al. ACTA PHARMACOLOGICA SINICA
- Increased food energy supply is more than sufficient to explain the US epidemic of obesity
- (2009) Boyd Swinburn et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Regulatory enzymes of mitochondrial β-oxidation as targets for treatment of the metabolic syndrome
- (2009) M. Schreurs et al. Obesity Reviews
- A moderate increase in carnitine palmitoyltransferase 1a activity is sufficient to substantially reduce hepatic triglyceride levels
- (2008) Maja Stefanovic-Racic et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Macromolecular Modeling with Rosetta
- (2008) Rhiju Das et al. Annual Review of Biochemistry
- C75 is converted to C75-CoA in the hypothalamus, where it inhibits carnitine palmitoyltransferase 1 and decreases food intake and body weight
- (2008) Paula Mera et al. BIOCHEMICAL PHARMACOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now