Species-specific disruption of STING-dependent antiviral cellular defenses by the Zika virus NS2B3 protease

Predominant role of IPS-1 over TRIF adaptor proteins in early innate immune response against Zika virus in mice

(2018) Jocelyne Piret et al.   JOURNAL OF GENERAL VIROLOGY

An evolutionary NS1 mutation enhances Zika virus evasion of host interferon induction

(2018) Hongjie Xia et al.   Nature Communications

Dengue viruses cleave STING in humans but not in nonhuman primates, their presumed natural reservoir

(2018) Alex C Stabell et al.   eLife

Endoplasmic Reticulum Protein SCAP Inhibits Dengue Virus NS2B3 Protease by Suppressing Its K27-Linked Polyubiquitylation

(2017) Heng Liu et al.   JOURNAL OF VIROLOGY

An update on Zika virus infection

(2017) David Baud et al.   LANCET

Evolutionary enhancement of Zika virus infectivity in Aedes aegypti mosquitoes

(2017) Yang Liu et al.   NATURE

Zika virus protection by a single low-dose nucleoside-modified mRNA vaccination

(2017) Norbert Pardi et al.   NATURE

Type III Interferon-Mediated Signaling Is Critical for Controlling Live Attenuated Yellow Fever Virus Infection In Vivo

(2017) Florian Douam et al.   mBio

Screening Bioactives Reveals Nanchangmycin as a Broad Spectrum Antiviral Active against Zika Virus

(2017) Keiko Rausch et al.   Cell Reports

The Natural Product Cavinafungin Selectively Interferes with Zika and Dengue Virus Replication by Inhibition of the Host Signal Peptidase

(2017) David Estoppey et al.   Cell Reports

Macaque monkeys in Zika virus research: 1947–present

(2017) Christina Newman et al.   Current Opinion in Virology

A novel Zika virus mouse model reveals strain specific differences in virus pathogenesis and host inflammatory immune responses

(2017) Shashank Tripathi et al.   PLoS Pathogens

Dengue virus NS2B protein targets cGAS for degradation and prevents mitochondrial DNA sensing during infection

(2017) Sebastian Aguirre et al.   Nature Microbiology

Zika virus evades interferon-mediated antiviral response through the co-operation of multiple nonstructural proteins in vitro

(2017) Yaoxing Wu et al.   Cell Discovery

Viperin is an important host restriction factor in control of Zika virus infection

(2017) Kylie H. Van der Hoek et al.   Scientific Reports

A Screen of FDA-Approved Drugs for Inhibitors of Zika Virus Infection

(2016) Nicholas J. Barrows et al.   Cell Host & Microbe

Zika Virus Targets Human STAT2 to Inhibit Type I Interferon Signaling

(2016) Alesha Grant et al.   Cell Host & Microbe

The cGAS-STING Defense Pathway and Its Counteraction by Viruses

(2016) Zhe Ma et al.   Cell Host & Microbe

A Mouse Model of Zika Virus Pathogenesis

(2016) Helen M. Lazear et al.   Cell Host & Microbe

Zika Virus Disrupts Neural Progenitor Development and Leads to Microcephaly in Mice

(2016) Cui Li et al.   Cell Stem Cell

Vaccine protection against Zika virus from Brazil

(2016) Rafael A. Larocca et al.   NATURE

Zika virus infection damages the testes in mice

(2016) Jennifer Govero et al.   NATURE

Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen

(2016) Miao Xu et al.   NATURE MEDICINE

Zika virus cell tropism in the developing human brain and inhibition by azithromycin

(2016) Hanna Retallack et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rapid development of a DNA vaccine for Zika virus

(2016) K. A. Dowd et al.   SCIENCE

MAVS-dependent host species range and pathogenicity of human hepatitis A virus

(2016) A. Hirai-Yuki et al.   SCIENCE

Protective efficacy of multiple vaccine platforms against Zika virus challenge in rhesus monkeys

(2016) P. Abbink et al.   SCIENCE

The Viral Polymerase Inhibitor 7-Deaza-2’-C-Methyladenosine Is a Potent Inhibitor of In Vitro Zika Virus Replication and Delays Disease Progression in a Robust Mouse Infection Model

(2016) Joanna Zmurko et al.   PLoS Neglected Tropical Diseases

Characterization of Lethal Zika Virus Infection in AG129 Mice

(2016) Matthew T. Aliota et al.   PLoS Neglected Tropical Diseases

A Susceptible Mouse Model for Zika Virus Infection

(2016) Stuart D. Dowall et al.   PLoS Neglected Tropical Diseases

Genetic Dissection of the Host Tropism of Human-Tropic Pathogens

(2015) Florian Douam et al.   Annual Review of Genetics

Interferon-λ restricts West Nile virus neuroinvasion by tightening the blood-brain barrier

(2015) Helen M. Lazear et al.   Science Translational Medicine

Hepatitis C virus NS4B blocks the interaction of STING and TBK1 to evade host innate immunity

(2013) Qiang Ding et al.   JOURNAL OF HEPATOLOGY

Completion of the entire hepatitis C virus life cycle in genetically humanized mice

(2013) Marcus Dorner et al.   NATURE

The global distribution and burden of dengue

(2013) Samir Bhatt et al.   NATURE

Recapitulation of the hepatitis C virus life-cycle in engineered murine cell lines

(2013) Alexander Vogt et al.   VIROLOGY

Emerging Infectious Diseases: Threats to Human Health and Global Stability

(2013) David M. Morens et al.   PLoS Pathogens

Hepatitis C virus NS4B protein targets STING and abrogates RIG-I-mediated type I interferon-dependent innate immunity

(2012) Sayuri Nitta et al.   HEPATOLOGY

Dengue Virus Targets the Adaptor Protein MITA to Subvert Host Innate Immunity

(2012) Chia-Yi Yu et al.   PLoS Pathogens

DENV Inhibits Type I IFN Production in Infected Cells by Cleaving Human STING

(2012) Sebastian Aguirre et al.   PLoS Pathogens

TheN-Ethyl-N-Nitrosourea-InducedGoldenticketMouse Mutant Reveals an Essential Function ofStingin theIn VivoInterferon Response toListeria monocytogenesand Cyclic Dinucleotides

(2010) John-Demian Sauer et al.   INFECTION AND IMMUNITY

A map of human genome variation from population-scale sequencing

(2010) Richard M. Durbin et al.   NATURE

STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity

(2009) Hiroki Ishikawa et al.   NATURE

ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization

(2009) W. Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Adaptor Protein MITA Links Virus-Sensing Receptors to IRF3 Transcription Factor Activation

(2008) Bo Zhong et al.   IMMUNITY

MPYS, a Novel Membrane Tetraspanner, Is Associated with Major Histocompatibility Complex Class II and Mediates Transduction of Apoptotic Signals

(2008) L. Jin et al.   MOLECULAR AND CELLULAR BIOLOGY

STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

(2008) Hiroki Ishikawa et al.   NATURE