Dengue virus NS2B protein targets cGAS for degradation and prevents mitochondrial DNA sensing during infection

A Proline-Rich N-Terminal Region of the Dengue Virus NS3 Is Crucial for Infectious Particle Production

(2016) Leopoldo G. Gebhard et al.   JOURNAL OF VIROLOGY

Subcellular Localizations of RIG-I, TRIM25, and MAVS Complexes

(2016) M. T. Sánchez-Aparicio et al.   JOURNAL OF VIROLOGY

A phosphomimetic-based mechanism of dengue virus to antagonize innate immunity

(2016) Ying Kai Chan et al.   NATURE IMMUNOLOGY

DNA Damage Primes the Type I Interferon System via the Cytosolic DNA Sensor STING to Promote Anti-Microbial Innate Immunity

(2015) Anetta Härtlova et al.   IMMUNITY

Mitochondrial DNA stress primes the antiviral innate immune response

(2015) A. Phillip West et al.   NATURE

Stable heteroplasmy at the single-cell level is facilitated by intercellular exchange of mtDNA

(2015) Anitha D. Jayaprakash et al.   NUCLEIC ACIDS RESEARCH

Dengue Virus Impairs Mitochondrial Fusion by Cleaving Mitofusins

(2015) Chia-Yi Yu et al.   PLoS Pathogens

The dengue virus conceals double-stranded RNA in the intracellular membrane to escape from an interferon response

(2014) Leo Uchida et al.   Scientific Reports

Modified Vaccinia Virus Ankara Triggers Type I IFN Production in Murine Conventional Dendritic Cells via a cGAS/STING-Mediated Cytosolic DNA-Sensing Pathway

(2014) Peihong Dai et al.   PLoS Pathogens

Cytosolic Sensing of Viruses

(2013) Delphine Goubau et al.   IMMUNITY

Adenovirus Detection by the cGAS/STING/TBK1 DNA Sensing Cascade

(2013) E. Lam et al.   JOURNAL OF VIROLOGY

Structural mechanism of cytosolic DNA sensing by cGAS

(2013) Filiz Civril et al.   NATURE

Cell intrinsic immunity spreads to bystander cells via the intercellular transfer of cGAMP

(2013) Andrea Ablasser et al.   NATURE

Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity

(2013) John W. Schoggins et al.   NATURE

The global distribution and burden of dengue

(2013) Samir Bhatt et al.   NATURE

Pivotal Roles of cGAS-cGAMP Signaling in Antiviral Defense and Immune Adjuvant Effects

(2013) X.-D. Li et al.   SCIENCE

Cyclic GMP-AMP Synthase Is an Innate Immune Sensor of HIV and Other Retroviruses

(2013) D. Gao et al.   SCIENCE

Structure of Human cGAS Reveals a Conserved Family of Second-Messenger Enzymes in Innate Immunity

(2013) Philip J. Kranzusch et al.   Cell Reports

Mapping single molecule sequencing reads using basic local alignment with successive refinement (BLASR): application and theory

(2012) Mark J Chaisson et al.   BMC BIOINFORMATICS

GENCODE: The reference human genome annotation for The ENCODE Project

(2012) J. Harrow et al.   GENOME RESEARCH

Endoplasmic reticulum–mitochondria contacts: function of the junction

(2012) Ashley A. Rowland et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway

(2012) L. Sun et al.   SCIENCE

Innate Immunity Evasion by Dengue Virus

(2012) Juliet Morrison et al.   Viruses-Basel

Dengue Virus Targets the Adaptor Protein MITA to Subvert Host Innate Immunity

(2012) Chia-Yi Yu et al.   PLoS Pathogens

DENV Inhibits Type I IFN Production in Infected Cells by Cleaving Human STING

(2012) Sebastian Aguirre et al.   PLoS Pathogens

Delayed Cytosolic Exposure of Japanese Encephalitis Virus Double-Stranded RNA Impedes Interferon Activation and Enhances Viral Dissemination in Porcine Cells

(2011) L. A. Espada-Murao et al.   JOURNAL OF VIROLOGY

A diverse range of gene products are effectors of the type I interferon antiviral response

(2011) John W. Schoggins et al.   NATURE

Dengue Virus-Induced Autophagy Regulates Lipid Metabolism

(2010) Nicholas S. Heaton et al.   Cell Host & Microbe

Dengue Virus Inhibits the Production of Type I Interferon in Primary Human Dendritic Cells

(2010) J. R. Rodriguez-Madoz et al.   JOURNAL OF VIROLOGY

Inhibition of the Type I Interferon Response in Human Dendritic Cells by Dengue Virus Infection Requires a Catalytically Active NS2B3 Complex

(2010) J. R. Rodriguez-Madoz et al.   JOURNAL OF VIROLOGY

Composition and Three-Dimensional Architecture of the Dengue Virus Replication and Assembly Sites

(2009) Sonja Welsch et al.   Cell Host & Microbe

NS5 of Dengue Virus Mediates STAT2 Binding and Degradation

(2009) J. Ashour et al.   JOURNAL OF VIROLOGY

The Adaptor Protein MITA Links Virus-Sensing Receptors to IRF3 Transcription Factor Activation

(2008) Bo Zhong et al.   IMMUNITY

Induction of p53-dependent and mitochondria-mediated cell death pathway by dengue virus infection of human and animal cells

(2008) A NASIRUDEEN et al.   MICROBES AND INFECTION