Metabolic shift from glycogen to trehalose promotes lifespan and healthspan inCaenorhabditis elegans
出版年份 2018 全文链接
标题
Metabolic shift from glycogen to trehalose promotes lifespan and healthspan inCaenorhabditis elegans
作者
关键词
-
出版物
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 115, Issue 12, Pages E2791-E2800
出版商
Proceedings of the National Academy of Sciences
发表日期
2018-03-07
DOI
10.1073/pnas.1714178115
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Glycogen controls Caenorhabditis elegans lifespan and resistance to oxidative stress
- (2017) Ivan Gusarov et al. Nature Communications
- Dietary Sugars and Endogenous Formation of Advanced Glycation Endproducts: Emerging Mechanisms of Disease
- (2017) Manuela Aragno et al. Nutrients
- daf-16/FoxO promotes gluconeogenesis and trehalose synthesis during starvation to support survival
- (2017) Jonathan D Hibshman et al. eLife
- Trehalose improves traumatic brain injury-induced cognitive impairment
- (2017) Stuart D. Portbury et al. PLoS One
- High glucose alters tendon homeostasis through downregulation of the AMPK/Egr1 pathway
- (2017) Yu-Fu Wu et al. Scientific Reports
- A high-glucose diet affects Achilles tendon healing in rats
- (2017) Stefanie Korntner et al. Scientific Reports
- A cross-sectional study of male and female C57BL/6Nia mice suggests lifespan and healthspan are not necessarily correlated
- (2016) Kathleen E. Fischer et al. Aging-US
- Advanced Glycation End-Products and Their Receptors: Related Pathologies, Recent Therapeutic Strategies, and a Potential Model for Future Neurodegeneration Studies
- (2016) Adi Pinkas et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Glucose-rich diet aggravates monocrotophos-induced dopaminergic neuronal dysfunction in Caenorhabditis elegans
- (2016) Chinnu Salim et al. JOURNAL OF APPLIED TOXICOLOGY
- Daily Intake of Trehalose Is Effective in the Prevention of Lifestyle-Related Diseases in Individuals with Risk Factors for Metabolic Syndrome
- (2016) Akiko MIZOTE et al. JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY
- Mystery solved: Trehalose kickstarts autophagy by blocking glucose transport
- (2016) Pablo Mardones et al. Science Signaling
- Trehalose inhibits solute carrier 2A (SLC2A) proteins to induce autophagy and prevent hepatic steatosis
- (2016) Brian J. DeBosch et al. Science Signaling
- Mystery solved: Trehalose kickstarts autophagy by blocking glucose transport
- (2016) Pablo Mardones et al. Science Signaling
- Trehalose inhibits solute carrier 2A (SLC2A) proteins to induce autophagy and prevent hepatic steatosis
- (2016) Brian J. DeBosch et al. Science Signaling
- Autophagy mediates pharmacological lifespan extension by spermidineand resveratrol
- (2016) Eugenia Morselli et al. Aging-US
- Trehalose, sucrose and raffinose are novel activators of autophagy in human keratinocytes through an mTOR-independent pathway
- (2016) Xu Chen et al. Scientific Reports
- SLC2A8 (GLUT8) is a mammalian trehalose transporter required for trehalose-induced autophagy
- (2016) Allyson L. Mayer et al. Scientific Reports
- High-glucose diets have sex-specific effects on aging in C. elegans: toxic to hermaphrodites but beneficial to males
- (2015) Marjorie R. Liggett et al. Aging-US
- Food for the Brain
- (2015) Charles S. Zuker CELL
- SREBP and MDT-15 protectC. elegansfrom glucose-induced accelerated aging by preventing accumulation of saturated fat
- (2015) Dongyeop Lee et al. GENES & DEVELOPMENT
- Glucose Induces Sensitivity to Oxygen Deprivation and Modulates Insulin/IGF-1 Signaling and Lipid Biosynthesis in Caenorhabditis elegans
- (2015) A. M. Garcia et al. GENETICS
- Glycogen Fuels Survival During Hyposmotic-Anoxic Stress in Caenorhabditis elegans
- (2015) J. C. LaMacchia et al. GENETICS
- Longevity Genes Revealed by Integrative Analysis of Isoform-Specificdaf-16/FoxOMutants ofCaenorhabditis elegans
- (2015) Albert Tzong-Yang Chen et al. GENETICS
- Uncoupling lifespan and healthspan inCaenorhabditis eleganslongevity mutants
- (2015) Ankita Bansal et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Integration of carbohydrate metabolism and redox state controls dauer larva formation in Caenorhabditis elegans
- (2015) Sider Penkov et al. Nature Communications
- FLCN and AMPK Confer Resistance to Hyperosmotic Stress via Remodeling of Glycogen Stores
- (2015) Elite Possik et al. PLoS Genetics
- mir-233 Modulates the Unfolded Protein Response in C. elegans during Pseudomonas aeruginosa Infection
- (2015) Li-Li Dai et al. PLoS Pathogens
- Longevity Genes Revealed by Integrative Analysis of Isoform-Specificdaf-16/FoxOMutants ofCaenorhabditis elegans
- (2015) Albert Tzong-Yang Chen et al. GENETICS
- Longevity pathways converge on autophagy genes to regulate life span inCaenorhabditis elegans
- (2014) Márton L. Tóth et al. Autophagy
- DAF-16 target identification in C. elegans: past, present and future
- (2014) Jennifer M. A. Tullet BIOGERONTOLOGY
- Dietary Sugar and Body Weight: Have We Reached a Crisis in the Epidemic of Obesity and Diabetes?
- (2014) George A. Bray et al. DIABETES CARE
- daf-16/FOXO and glod-4/glyoxalase-1 are required for the life-prolonging effect of human insulin under high glucose conditions in Caenorhabditis elegans
- (2014) Michael Mendler et al. DIABETOLOGIA
- Pompe Disease
- (2014) Majed Dasouki et al. NEUROLOGIC CLINICS
- Glucose feeding during development aggravates the toxicity of the organophosphorus insecticide Monocrotophos in the nematode, Caenorhabditis elegans
- (2014) Chinnu Salim et al. PHYSIOLOGY & BEHAVIOR
- Added Sugar Intake and Cardiovascular Diseases Mortality Among US Adults
- (2014) Quanhe Yang et al. JAMA Internal Medicine
- The TFEB orthologue HLH-30 regulates autophagy and modulates longevity in Caenorhabditis elegans
- (2013) Louis R. Lapierre et al. Nature Communications
- Energy and Fructose From Beverages Sweetened With Sugar or High-Fructose Corn Syrup Pose a Health Risk for Some People
- (2013) George A. Bray Advances in Nutrition
- Glycogen and its metabolism: some new developments and old themes
- (2012) Peter J. Roach et al. BIOCHEMICAL JOURNAL
- Paternal dietary restriction affects progeny fat content in Caenorhabditis elegans
- (2012) Claudia Miersch et al. IUBMB LIFE
- A review of chemical composition and nutritional value of wild-growing and cultivated mushrooms
- (2012) Pavel Kalač JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
- Lessons from C. elegans: signaling pathways for longevity
- (2012) Louis R. Lapierre et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Trehalose Renders the Dauer Larva of Caenorhabditis elegans Resistant to Extreme Desiccation
- (2011) Cihan Erkut et al. CURRENT BIOLOGY
- O-Linked-N-Acetylglucosamine Cycling and Insulin Signaling Are Required for the Glucose Stress Response inCaenorhabditis elegans
- (2011) Michelle A. Mondoux et al. GENETICS
- High glucose diets shorten lifespan ofCaenorhabditis elegansvia ectopic apoptosis induction
- (2011) Shin Sik Choi Nutrition Research and Practice
- Trehalose extends longevity in the nematode Caenorhabditis elegans
- (2010) Yoko Honda et al. AGING CELL
- DamID in C. elegans reveals longevity-associated targets of DAF-16/FoxO
- (2010) Eugene Schuster et al. Molecular Systems Biology
- A new DAF-16 isoform regulates longevity
- (2010) Eun-Soo Kwon et al. NATURE
- The first long-lived mutants: discovery of the insulin/IGF-1 pathway for ageing
- (2010) C. Kenyon PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- Glucose Shortens the Life Span of C. elegans by Downregulating DAF-16/FOXO Activity and Aquaporin Gene Expression
- (2009) Seung-Jae Lee et al. Cell Metabolism
- Adaptive Sugar Provisioning Controls Survival of C. elegans Embryos in Adverse Environments
- (2009) Harold N. Frazier et al. CURRENT BIOLOGY
- C. elegans as Model for the Study of High Glucose- Mediated Life Span Reduction
- (2009) A. Schlotterer et al. DIABETES
- Mutations in the glucose-6-phosphatase-α (G6PC) gene that cause type Ia glycogen storage disease
- (2008) Janice Y. Chou et al. HUMAN MUTATION
- A Role for Autophagy in the Extension of Lifespan by Dietary Restriction in C. elegans
- (2008) Malene Hansen et al. PLoS Genetics
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More