CD52 glycan binds the proinflammatory B box of HMGB1 to engage the Siglec-10 receptor and suppress human T cell function

C1q and HMGB1 reciprocally regulate human macrophage polarization

(2016) M. Son et al.   BLOOD

Alemtuzumab for Multiple Sclerosis

(2016) Mark D. Willis et al.   Current Neurology and Neuroscience Reports

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(2014) Daniel Antoine et al.   MOLECULAR MEDICINE

T cell regulation mediated by interaction of soluble CD52 with the inhibitory receptor Siglec-10

(2013) Esther Bandala-Sanchez et al.   NATURE IMMUNOLOGY

Conditional ablation of HMGB1 in mice reveals its protective function against endotoxemia and bacterial infection

(2013) H. Yanai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Siglecs and Immune Regulation

(2012) Shiv Pillai et al.   Annual Review of Immunology

Glycan Microarrays for Decoding the Glycome

(2011) Cory D. Rillahan et al.   Annual Review of Biochemistry

HMGB1 Is a Therapeutic Target for Sterile Inflammation and Infection

(2011) Ulf Andersson et al.   Annual Review of Immunology

Letter to the Glyco-Forum: Effective glycoanalysis with Maackia amurensis lectins requires a clear understanding of their binding specificities

(2011) C. Geisler et al.   GLYCOBIOLOGY

CD24 and Siglec-10 Selectively Repress Tissue Damage-Induced Immune Responses

(2009) G.-Y. Chen et al.   SCIENCE

Cd52, known as a major maturation-associated sperm membrane antigen secreted from the epididymis, is not required for fertilization in the mouse

(2008) Ryo Yamaguchi et al.   GENES TO CELLS