Susceptibility of brain atrophy toTRIB3in Alzheimer’s disease, evidence from functional prioritization in imaging genetics

Adiposity, Type 2 Diabetes, and Alzheimer's Disease

(2017) José A. Luchsinger et al.   JOURNAL OF ALZHEIMERS DISEASE

Pre-Clinical Detection of Alzheimer's Disease Using FDG-PET, with or without Amyloid Imaging

(2017) Lisa Mosconi et al.   JOURNAL OF ALZHEIMERS DISEASE

Skeletal Muscle TRIB3 Mediates Glucose Toxicity in Diabetes and High- Fat Diet–Induced Insulin Resistance

(2016) Wei Zhang et al.   DIABETES

Tribbles Pseudokinase 3 Induces Both Apoptosis and Autophagy in Amyloid-β-induced Neuronal Death

(2016) Suraiya Saleem et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Insulin signalling in Alzheimer′s disease and diabetes: from epidemiology to molecular links

(2016) E. M. Ribe et al.   JOURNAL OF INTERNAL MEDICINE

The Ensembl gene annotation system

(2016) Bronwen L. Aken et al.   Database-The Journal of Biological Databases and Curation

LDlink: a web-based application for exploring population-specific haplotype structure and linking correlated alleles of possible functional variants: Fig. 1.

(2015) Mitchell J. Machiela et al.   BIOINFORMATICS

A Novel Approach to High-Quality Postmortem Tissue Procurement: The GTEx Project

(2015) Latarsha J. Carithers et al.   BIOPRESERVATION AND BIOBANKING

Vascular amyloidosis impairs the gliovascular unit in a mouse model of Alzheimer’s disease

(2015) Ian F. Kimbrough et al.   BRAIN

Trib3 Is Elevated in Parkinson's Disease and Mediates Death in Parkinson's Disease Models

(2015) P. Aime et al.   JOURNAL OF NEUROSCIENCE

Compromised autophagy and neurodegenerative diseases

(2015) Fiona M. Menzies et al.   NATURE REVIEWS NEUROSCIENCE

Il10 Deficiency Rebalances Innate Immunity to Mitigate Alzheimer-Like Pathology

(2015) Marie-Victoire Guillot-Sestier et al.   NEURON

TRB3 links insulin/IGF to tumour promotion by interacting with p62 and impeding autophagic/proteasomal degradations

(2015) Fang Hua et al.   Nature Communications

A Novel Approach to High-Quality Postmortem Tissue Procurement: The GTEx Project

(2015) Latarsha J. Carithers et al.   Biopreservation and Biobanking

A Genome-wide Gene-Expression Analysis and Database in Transgenic Mice during Development of Amyloid or Tau Pathology

(2015) Mar Matarin et al.   Cell Reports

In vivo tau imaging: Obstacles and progress

(2014) Victor L. Villemagne et al.   Alzheimers & Dementia

Inflammation, defective insulin signaling, and neuronal dysfunction in Alzheimer's disease

(2014) Sergio T. Ferreira et al.   Alzheimers & Dementia

Amyloid Imaging in Aging and Dementia: Testing the Amyloid HypothesisIn Vivo

(2014) G. D. Rabinovici et al.   BEHAVIOURAL NEUROLOGY

A review of multivariate analyses in imaging genetics

(2014) Jingyu Liu et al.   Frontiers in Neuroinformatics

A feed-forward loop involving Trib3, Akt and FoxO mediates death of NGF-deprived neurons

(2013) N Zareen et al.   CELL DEATH AND DIFFERENTIATION

APOE and BCHE as modulators of cerebral amyloid deposition: a florbetapir PET genome-wide association study

(2013) V K Ramanan et al.   MOLECULAR PSYCHIATRY

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

(2013) Jean-Charles Lambert et al.   NATURE GENETICS

PRoNTo: Pattern Recognition for Neuroimaging Toolbox

(2013) J. Schrouff et al.   NEUROINFORMATICS

GLIDE: GPU-Based Linear Regression for Detection of Epistasis

(2012) Tony Kam-Thong et al.   HUMAN HEREDITY

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

(2012)   NATURE GENETICS

Significant correlation between a set of genetic polymorphisms and a functional brain network revealed by feature selection and sparse Partial Least Squares

(2012) Édith Le Floch et al.   NEUROIMAGE

Identification of gene pathways implicated in Alzheimer's disease using longitudinal imaging phenotypes with sparse regression

(2012) Matt Silver et al.   NEUROIMAGE

Interactions of Pathological Hallmark Proteins

(2011) Judit Oláh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Quality control parameters on a large dataset of regionally dissected human control brains for whole genome expression studies

(2011) Daniah Trabzuni et al.   JOURNAL OF NEUROCHEMISTRY

Whole genome association scan for genetic polymorphisms influencing information processing speed

(2010) Michelle Luciano et al.   BIOLOGICAL PSYCHOLOGY

How does diabetes accelerate Alzheimer disease pathology?

(2010) Catrina Sims-Robinson et al.   Nature Reviews Neurology

The clinical use of structural MRI in Alzheimer disease

(2010) Giovanni B. Frisoni et al.   Nature Reviews Neurology

Discovering genetic associations with high-dimensional neuroimaging phenotypes: A sparse reduced-rank regression approach

(2010) Maria Vounou et al.   NEUROIMAGE

Voxelwise genome-wide association study (vGWAS)

(2010) Jason L. Stein et al.   NEUROIMAGE

Genetic Analysis of Alzheimer’s Disease in the Uppsala Longitudinal Study of Adult Men

(2009) Vilmantas Giedraitis et al.   DEMENTIA AND GERIATRIC COGNITIVE DISORDERS

Machine learning in genome-wide association studies

(2009) Silke Szymczak et al.   GENETIC EPIDEMIOLOGY

Circos: An information aesthetic for comparative genomics

(2009) M. Krzywinski et al.   GENOME RESEARCH

Hippocampal Atrophy as a Quantitative Trait in a Genome-Wide Association Study Identifying Novel Susceptibility Genes for Alzheimer's Disease

(2009) Steven G. Potkin et al.   PLoS One

E3 ubiquitin ligase SIAH1 mediates ubiquitination and degradation of TRB3

(2008) Ying Zhou et al.   CELLULAR SIGNALLING

Contextual Regulation of Inflammation: A Duet by Transforming Growth Factor-β and Interleukin-10

(2008) Ming O. Li et al.   IMMUNITY

Candidate Single-Nucleotide Polymorphisms From a Genomewide Association Study of Alzheimer Disease

(2007) Hao Li et al.   ARCHIVES OF NEUROLOGY

Combining fMRI and SNP data to investigate connections between brain function and genetics using parallel ICA

(2007) Jingyu Liu et al.   HUMAN BRAIN MAPPING