Viral protein Nef is detected in plasma of half of HIV-infected adults with undetectable plasma HIV RNA

Nef is secreted in exosomes from Nef.GFP-expressing and HIV-1-infected human astrocytes

(2017) Pia Pužar Dominkuš et al.   JOURNAL OF NEUROVIROLOGY

Single-Cell Characterization of Viral Translation-Competent Reservoirs in HIV-Infected Individuals

(2016) Amy E. Baxter et al.   Cell Host & Microbe

Kinetics of HIV-1 Latency Reversal Quantified on the Single-Cell Level Using a Novel Flow-Based Technique

(2016) G. Martrus et al.   JOURNAL OF VIROLOGY

Defective proviruses rapidly accumulate during acute HIV-1 infection

(2016) Katherine M Bruner et al.   NATURE MEDICINE

HIV-1 Nef: Taking Control of Protein Trafficking

(2016) Estela A. Pereira et al.   TRAFFIC

HIV-Nef and ADAM17-Containing Plasma Extracellular Vesicles Induce and Correlate with Immune Pathogenesis in Chronic HIV Infection

(2016) Jung-Hyun Lee et al.   EBioMedicine

Exosomes Are Unlikely Involved in Intercellular Nef Transfer

(2015) Xiaoyu Luo et al.   PLoS One

Increase in 2–Long Terminal Repeat Circles and Decrease in D-dimer After Raltegravir Intensification in Patients With Treated HIV Infection: A Randomized, Placebo-Controlled Trial

(2013) Hiroyu Hatano et al.   JOURNAL OF INFECTIOUS DISEASES

The end of AIDS: HIV infection as a chronic disease

(2013) Steven G Deeks et al.   LANCET

HIV Nef, Paxillin, and Pak1/2 Regulate Activation and Secretion of TACE/ADAM10 Proteases

(2013) Jung-Hyun Lee et al.   MOLECULAR CELL

Ability of HIV-1 Nef to downregulate CD4 and HLA class I differs among viral subtypes

(2013) Jaclyn K Mann et al.   Retrovirology

How to best measure HIV reservoirs?

(2013) Christine Rouzioux et al.   Current Opinion in HIV and AIDS

Comparative Analysis of Measures of Viral Reservoirs in HIV-1 Eradication Studies

(2013) Susanne Eriksson et al.   PLoS Pathogens

Detection of HIV gp120 in Plasma During Early HIV Infection Is Associated with Increased Proinflammatory and Immunoregulatory Cytokines

(2010) Jenna Rychert et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

HIV Type 1 Nef Is Released from Infected Cells in CD45+ Microvesicles and Is Present in the Plasma of HIV-Infected Individuals

(2010) A.D. Raymond et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

HIV-1 replication and immune dynamics are affected by raltegravir intensification of HAART-suppressed subjects

(2010) Maria J Buzón et al.   NATURE MEDICINE

Massive Secretion by T Cells Is Caused by HIV Nef in Infected Cells and by Nef Transfer to Bystander Cells

(2009) Claudia Muratori et al.   Cell Host & Microbe

HIV Nef is Secreted in Exosomes and Triggers Apoptosis in Bystander CD4+ T Cells

(2009) Metka Lenassi et al.   TRAFFIC